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Department of Biomedicine🔬🧪

@biomedizin.unibas.ch

200 followers 59 following 28 posts

As a joint venture of the University of Basel and the University Hospitals Basel, the Department of Biomedicine (DBM) brings together basic and clinical scientists to advance our understanding of health and disease.

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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Feb 4

🔬 Meet the people behind the discoveries! Want to connect? Explore their latest research and insights and connect with our researchers on Bluesky.

go.bsky.app/3jJYova

#MeetOurResearchers #DBM #DepartmentofBiomedicine

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 7d

🚀 Breakthrough in #ProstateCancer research from @biomedizin.unibas.ch published in
@cp-cellreports.bsky.social! Matrigel-free PDOs preserve patient-specific cell populations. New single-cell atlas (PPScA) maps heterogeneity + reveals pathways altered in vitro.

Fluorescent microscopy image of antibody-labeled patient-derived organoids (PDOs), captured at Le Magnen Lab.

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 9d

✨ Good news! The eleventh issue of our DBM newsletter is out! We hope you enjoy it! 👇🏼👇🏼👇🏼
issuu.com/departementb...

#Newsletter #Research #Science #Biomedicine #TeamDBM

Newsletter Issue 11

issuu.com

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 20d

Researchers @biomedizin.unibas.ch developed cartilage implants from nasal septum cells, and showed that allowing them to mature for two weeks improved outcomes. 🔬Congratulations to all contributors.
doi.org/10.1126/scit...

#Immunotherapy #CancerImmunology #FusionProtein #PD1IL2v #TCellTherapy

© Martin Oeggerli (www.Micronaut.ch) 2019-2025, with Marcel Philipp Trefny, and Prof. Alfred Zippelius, Cancer Immunology, University Hospital Basel, Pathology University Hospital Basel, and C-CINA, Biozentrum, University Basel

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · 27d

New in Haematologica: Researchers at binderlab.bsky.social report a mutation-specific immunotherapy for high-risk CLL. A bispecific antibody (BiTE) redirects T cells to target IGLV3-21^R110+ leukemia cells—killing malignant cells while sparing healthy B cells.
Link: doi.org/10.3324/haem...

Bispecific antibodies as a potential off-the-shelf immunotherapy for high-risk CLL patients (Image Adobe Stock)

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Sep 4

Four DBM researchers at the University of Basel just secured ERC Starting Grants!🎉

A huge congratulations to Jean-Christophe Beltra, Mariana Borsa @nanaborsa.bsky.social , Magdalena Sznurkowska & Tobias Weiss.

🔗 Full news:
biomedizin.unibas.ch/en/communica...

@erc.europa.eu #ERCStG

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Sep 2

🚀 Welcome Prof. Dr. Marc Aurel Busche @marcaurelbusche.bsky.social to the DBM, University of Basel!

He’ll head the Brain Ageing & Neurodegeneration Lab, focusing on Alzheimer’s and brain circuit dysfunction. Read more: 🔗 biomedizin.unibas.ch/en/newsdetai...

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Aug 25

🎊Cheers to 25 Years of Discovery @biomedizin.unibas.ch !
Since 2000, we’ve grown into one of Switzerland’s top translational research hubs — thanks to our brilliant teams & community.
We celebrated with music, laughter, science & soul. Here’s to the next 25.💙
biomedizin.unibas.ch/en/newsdetai...

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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Aug 21

🏆 Dr. Laurentz Schuhknecht @zampierilab.bsky.social wins DBM Research Prize; Johanna Nimmerfroh (Läubli Lab) earns 1st Best Presentation Award at our Summer Symposium. Congratulations! 🎉

biomedizin.unibas.ch/en/communica...

#DBMPrize #BestPresentationAward #ResearchExcellence

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Aug 20

We are delighted to welcome you to the Department of Biomedicine at the University of Basel @unibas.ch soon! 🧬 ✨

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Aug 20

The 2025 DBM Summer Symposium is happening today! There will be a keynote by Prof. Mustafa Khammash @eth-bsse.bsky.social , 17 short talks, and the presentation of the DBM Research Prize 2024 and the Best Presentation Award 2025. 🧬🏆
Big thanks to all involved!
#DBMSymposium2025 #Science #TeamDBM

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Aug 12

Congrats to Mascha Binder & her team @binderlab.bsky.social‬ on their new paper showing that blood-based inflammation markers-like IL-6 & cfDNA-are better than PD-L1 at predicting immunotherapy outcomes in head & neck cancer.A move toward smarter, tailored treatments. www.nature.com/articles/s41...

Inflammation and limited adaptive immunity predict worse outcomes on immunotherapy in head and neck cancer - npj Precision Oncology

npj Precision Oncology - Inflammation and limited adaptive immunity predict worse outcomes on immunotherapy in head and neck cancer

www.nature.com

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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Jul 1

🚀 We’re thrilled to welcome Prof. Dr. Valérie Hilgers (hilgerslab.bsky.social) to the DBM! She’ll head the RNA Biology & Neurogenetics Lab, investigating how RNA regulation drives brain development and function. ERC Consolidator Grant 2024 included. Read more: 🔗 biomedizin.unibas.ch/en/communica...

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Jun 17

Meet our Expert Jürg Schwaller from the Childhood Leukemia Lab at the @Department of Biomedicine. Today he shares his research and vision for AML treatment strategies. Read more in our Blog with our Expert.

Blog with our Expert: biomedizin.unibas.ch/en/communica...

#AML #Leukemia #Cancerresearch

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Jun 6

Big things are rising in Basel 🏗️

The new DBM building will bring researchers together under one roof, with a focus on collaboration, comfort, and climate-conscious design - a real boost for biomedical science in Switzerland.

#ScienceForTheFuture #DBM #Basel

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · May 27

The 10th Golden Edition of our DBM Newsletter is out now. 📰✨ A special printed copy was handed out at the 'Laying of the Foundation Stone Ceremony' on May 23 as a commemorative keepsake.
Check it out here 👉 issuu.com/departementb...

@biomedizin.unibas.ch #Newsletter #Research #TeamDBM

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · May 26

SUM-seq: New single-cell method by @biomedizin.unibas.ch , @embl.org , @au.dk ‬‬ and Tampere university enables large-scale analysis of gene activity & DNA accessibility across millions of cells.
Congrats Prof. Zaugg & collaborators!‬‬‬‬‬‬

🔗 www.nature.com/articles/s41...

Single-cell ultra-high-throughput multiplexed chromatin and RNA profiling reveals gene regulatory dynamics - Nature Methods

This work presents SUM-seq, an ultra-high-throughput method for co-profiling chromatin accessibility and gene expression in single nuclei across multiplexed samples, advancing the study of gene regula...

www.nature.com

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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · May 23

🚧 Major milestone for the Department of Biomedicine: the foundation stone for the new DBM research building has been laid! A symbol of collaboration, innovation & sustainability, the new building is set to open in 2031.
Read more: biomedizin.unibas.ch/en/newsdetai...
#UniversityofBasel #DBM

Prof. Dr. Ivan Martin, Head of the Department of Biomedicine; Cantonal Councillor Mustafa Atici, Head of the Basel-Stadt Department of Education; Cantonal Councillor Monica Gschwind, Head of the Basel-Landschaft Department of Education, Culture and Sport; Dr. Rolf Borner, Director of Infrastructure & Operations at the University of Basel; Marc Brülhart, Head of Building Construction German-speaking Switzerland & Head of the Northwest Region Implenia; Dr. Beat Oberlin, President of the University Council of the University of Basel. (From left, photo: University of Basel, Christian Flierl)

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Apr 1

🚀 Thrilled to welcome Professor Dr. Pietro Cippà to the DBM team! As the new Professor of Nephrology at the University of Basel and Head of our Nephrology Lab, he’s set to drive transformative breakthroughs in kidney repair and transplant immunology. Read more: 🔗 biomedizin.unibas.ch/en/communica...

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Mar 31

New Research on LSD Microdosing & ADHD
A placebo-controlled study from @biomedizin.unibas.ch found no significant benefit of LSD microdosing for ADHD. Symptom improvements were driven by expectation rather than the drug itself. Congrats to Prof. Dr. Liechti & team! 🔗 jamanetwork.com/journals/jam...

Safety and Efficacy of Repeated Low-Dose LSD for ADHD Treatment in Adults

This double-blind, placebo-controlled randomized clinical trial determines the safety and efficacy of repeated low doses of lysergic acid diethylamide (LSD) in reducing attention-deficit/hyperactivity...

jamanetwork.com

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Mar 6

Researchers @biomedizin.unibas.ch developed cartilage implants from nasal septum cells, and showed that allowing them to mature for two weeks improved clinical outcomes. Cartilage tissue engineering matters!

🔬Congratulations to all contributors.

🔗 www.science.org/doi/10.1126/...

Clinical relevance of engineered cartilage maturation in a randomized multicenter trial for articular cartilage repair

Engineered hyaline-like cartilage tissues are superior to immature cell-based grafts for the therapy of cartilage defects in the human knee.

www.science.org

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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Feb 20

🔬 Science works better when people work together! 26 researchers and core facility heads from @fmiscience.bsky.social & biomedizin.unibas.ch came together for a day of innovation and collaboration! The meeting covered a wide range of research areas and we're excited to see what comes next! 👏

Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Feb 13

🔬 Key Regulators of Cell Fate Identified. Researchers from biomedizin.unibas.ch, embl.org & dkfz.bsky.social reveal that safeguard repressors like PROX1 can preserve cell identity & prevent liver cancer. Study by Aryan Kamal & Bryce Lim. 👉
🔗 www.nature.com/articles/s41...
@naturegenet.bsky.social

Here, a puppeteer’s hands control the mountain ridges in Waddington’s illustration of cell fate commitment, adding another detail to our understanding of cell fate. Credit: Daniela Velasco/EMBL.

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Reposted by Department of Biomedicine🔬🧪

Zampieri Lab @zampierilab.bsky.social · Feb 12

We are seeking for a talented semester or master student for a computational project on antimicrobial effects of drugs. Check it out!

www.zampierilab.org/join-us/

Join us - Zampieri Lab

Interested to join our lab? Feel free to inquire about open positions or semester/master projects in our lab. We are always looking for highly motivated Master and Bachelor Students. We continuously o...

www.zampierilab.org

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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Feb 12

🔬 AAV-Based Lymphocyte Depletion Reveals Key B Cell-CD8+ T Cell Synergy in Chronic Viral Infection as shown by Anna Lena Kastner (Pinschewer Lab biomedizin.unibas.ch) & colleagues.

🔗 Read more: www.cell.com/immunity/pdf...

@cp-immunity.bsky.social
#Immunology #AAV #Bcells #Tcells #ViralInfection

Durable Lymphocyte Subset Elimination to Decipher Immune Control of Chronic Viral Infection (Image: Adobe Stock, KI)

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Department of Biomedicine🔬🧪 @biomedizin.unibas.ch · Feb 11

🌟 Happy International Day of Women & Girls in Science! 👩‍🔬🔬 Only 33% of researchers worldwide are women—STEM still has barriers. For its 10th year, we’re celebrating 20 inspiring women from our Institute! ✨

Watch & share! 🔗
vimeo.com/1055511010?s...

#IDWGS #Feb11

International Day of Women and Girls in Science 2025

This is "International Day of Women and Girls in Science 2025" by Department of Biomedicine on Vimeo, the home for high quality videos and the people who…

vimeo.com

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