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Reposted by Bionic Vision Lab

Michael Beyeler @mbeyeler.bsky.social · 12d

👁️🧠 New preprint: We demonstrate the first data-driven neural control framework for a visual cortical implant in a blind human!

TL;DR Deep learning lets us synthesize efficient stimulation patterns that reliably evoke percepts, outperforming conventional calibration.

www.biorxiv.org/content/10.1...

Diagram showing three ways to control brain activity with a visual prosthesis. The goal is to match a desired pattern of brain responses. One method uses a simple one-to-one mapping, another uses an inverse neural network, and a third uses gradient optimization. Each method produces a stimulation pattern, which is tested in both computer simulations and in the brain of a blind participant with an implant. The figure shows that the neural network and gradient methods reproduce the target brain activity more accurately than the simple mapping.

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Bionic Vision Lab @bionicvisionlab.org · 21d

As federal research funding faces steep cuts, UC scientists are pushing brain-computer interfaces forward: restoring speech after ALS, easing Parkinson’s symptoms, and improving bionic vision with AI (that’s us 👋 at @ucsantabarbara.bsky.social).

🧠 www.universityofcalifornia.edu/news/thrilli...

Thrilling progress in brain-computer interfaces from UC labs

UC researchers and the patients they work with are showing the world what's possible when the human mind and advanced computers meet.

www.universityofcalifornia.edu

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Reposted by Bionic Vision Lab

Michael Beyeler @mbeyeler.bsky.social · Aug 2

Excited to share that I’ve been promoted to Associate Professor with tenure at UCSB!

Grateful to my mentors, students, and funders who shaped this journey and to @ucsantabarbara.bsky.social for giving the Bionic Vision Lab a home!

Full post: www.linkedin.com/posts/michae...

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Reposted by Bionic Vision Lab

Michael Beyeler @mbeyeler.bsky.social · Jul 16

At #EMBC2025? Come check out two talks from my lab in tomorrow’s Sensory Neuroprostheses session!

🗓️ Thurs July 17 · 8-10AM · Room B3 M3-4
🧠 Efficient threshold estimation
🧑🔬 Deep human-in-the-loop optimization

🔗 embc.embs.org/2025/program/
#BionicVision #NeuroTech #IEEE #EMBS

Program – EMBC 2025

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embc.embs.org

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Bionic Vision Lab @bionicvisionlab.org · Jul 13

🧠 Building on Roksana Sadeghi’s work: Calibrating retinal implants is slow and tedious. Can Gaussian Process Regression (GPR) guide smarter sampling?

✅ GPR + spatial sampling = fewer trials, same accuracy
🔁 Toward faster, personalized calibration

🔗 bionicvisionlab.org/publications...

#EMBC2025

Efficient spatial estimation of perceptual thresholds for retinal implants via Gaussian process regression | Bionic Vision Lab

We propose a Gaussian Process Regression (GPR) framework to predict perceptual thresholds at unsampled locations while leveraging uncertainty estimates to guide adaptive sampling.

bionicvisionlab.org

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Bionic Vision Lab @bionicvisionlab.org · Jul 13

🎓 Proud of our undergrad(!) Eirini Schoinas for leading this:
bionicvisionlab.org/publications...

🧠 Human-in-the-loop optimization (HILO) works in silico—but does it hold up with real people?
✅ HILO outperformed naïve and deep encoders
🔁 A step toward personalized #BionicVision

#EMBC2025

Evaluating deep human-in-the-loop optimization for retinal implants using sighted participants | Bionic Vision Lab

We evaluate HILO using sighted participants viewing simulated prosthetic vision to assess its ability to optimize stimulation strategies under realistic conditions.

bionicvisionlab.org

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Bionic Vision Lab @bionicvisionlab.org · Jul 13

👁️⚡ Headed to #EMBC2025? Catch two of our lab’s talks on optimizing retinal implants!

📍 Sensory Neuroprostheses
🗓️ Thurs July 17 · 8-10AM · Room B3 M3-4
🧠 Efficient threshold estimation
🧑🔬 Deep human-in-the-loop optimization

🔗 embc.embs.org/2025/program/
#BionicVision #NeuroTech #IEEE #EMBS #Retina

Program – EMBC 2025

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embc.embs.org

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Bionic Vision Lab @bionicvisionlab.org · Jul 9

This matters. Checkerboard rastering:

✔️ works across tasks
✔️ requires no fancy calibration
✔️ is hardware-agnostic

A low-cost, high-impact tweak that could make future visual prostheses more usable and more intuitive.

#BionicVision #BCI #NeuroTech

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Bionic Vision Lab @bionicvisionlab.org · Jul 9

✅ Checkerboard consistently outperformed the other patterns—higher accuracy, lower difficulty, fewer motion artifacts.

💡 Why? More spatial separation between activations = less perceptual interference.

It even matched performance of the ideal “no raster” condition, without breaking safety rules.

Boxplots showing task accuracy for two experimental tasks—Letter Recognition and Motion Discrimination—grouped by five raster patterns: No Raster (blue), Checkerboard (orange), Vertical (green), Horizontal (brown), and Random (pink). Each colored boxplot shows the median, interquartile range, and individual participant data points.

In both tasks, Checkerboard and No Raster yield the highest median accuracy.

Horizontal and Random patterns perform the worst, with more variability and lower scores.

Significant pairwise differences (p < .05) are indicated by horizontal bars above the plots, showing that Checkerboard significantly outperforms Random and Horizontal in both tasks.

A dashed line at 0.125 marks chance-level performance (1 out of 8).

These results suggest Checkerboard rastering improves perceptual performance compared to conventional or unstructured patterns.

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Bionic Vision Lab @bionicvisionlab.org · Jul 9

We ran a simulated prosthetic vision study in immersive VR using gaze-contingent, psychophysically grounded models of epiretinal implants.

🧪 Powered by BionicVisionXR.
📐 Modeled 100-electrode Argus-like array.
👀 Realistic phosphene appearance, eye/head tracking.

Diagram showing the four-step pipeline for simulating prosthetic vision in VR.
Step 1: A virtual camera captures the user’s view, guided by eye gaze. The image is converted to grayscale and blurred for preprocessing.
Step 2: The preprocessed image is mapped onto a simulated retinal implant with 100 electrodes. Electrodes are activated based on local image intensity and grouped into raster groups. Raster Group 1 is highlighted.
Step 3: Simulated perception is shown with and without rastering. Without rastering (top), all electrodes are active, producing a more complete but unrealistic percept. With rastering (bottom), only 20 electrodes are active per frame, resulting in a temporally fragmented percept. Phosphene shape depends on parameters for spatial spread (ρ) and elongation (λ).
Step 4: The rendered percept is updated with temporal effects and presented through a virtual reality headset.

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Bionic Vision Lab @bionicvisionlab.org · Jul 9

Checkerboard rastering has been used in #BCI and #NeuroTech applications, often based on intuition.

But is it actually better, or just tradition?

No one had rigorously tested how these patterns impact perception in visual prostheses.

So we did.

Raster pattern configurations used in the study, shown as 10×10 electrode grids labeled with numbers 1 through 5, representing five sequentially activated timing groups.

1. Horizontal: Each row of electrodes belongs to one group, with activation proceeding top to bottom.

2. Vertical: Each column is a group, activated left to right.

3. Checkerboard: Electrode groups are arranged to maximize spatial separation, forming a checkerboard-like layout.

4. Random: Group assignments are randomly distributed across the grid, with no spatial structure. This pattern was re-randomized every five frames to test unstructured activation.
Each group is represented with different shades of gray and labeled numerically to indicate activation order.

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Bionic Vision Lab @bionicvisionlab.org · Jul 9

👁️🧠 New paper alert!

We show that checkerboard-style electrode activation improves perceptual clarity in simulated prosthetic vision—outperforming other patterns in both letter and motion tasks.

Less bias, more function, same safety.

🔗 doi.org/10.1088/1741...

#BionicVision #NeuroTech

Raster patterns in simulated prosthetic vision. On the left, a natural scene of a yellow car is shown, followed by its transformation into a prosthetic vision simulation using a 10×10 grid of electrodes (red dots). Below this, a zoomed-in example shows the resulting phosphene pattern. To comply with safety constraints, electrodes are divided into five spatial groups activated sequentially across ~220 milliseconds. Each row represents a different raster pattern: vertical (columns activated left to right), horizontal (rows top to bottom), checkerboard (spatially maximized separation), and random (reshuffled every five frames). For each pattern, five panels show how the scene is progressively built across the five raster groups. Vertical and horizontal patterns show strong directional streaking. Checkerboard shows more uniform activation and perceptual clarity. Random appears spatially noisy and inconsistent.

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Bionic Vision Lab @bionicvisionlab.org · Jun 24

🎙️Our very own Lily Turkstra was featured on WYPL-FM’s Eye on Vision podcast to discuss how blind individuals use assistive tech at home, from tactile labels to digital tools.

📻 Listen: eyeonvision.blogspot.com/2025/05/assi...
📰 Read: bionicvisionlab.org/publications...

#BlindTech #Accessibility

Assistive Technology Use In The Home and AI and Adaptive Optics Ophthalmoscopes

Lily Turkstra (University of California - Santa Barbara) Dr. Johnny Tam (National Eye Institute - Bethesda, MD) Lily Turkstra , PhD Student,...

eyeonvision.blogspot.com

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Reposted by Bionic Vision Lab

bionic-vision.org @bionic-vision.org · Jun 12

👁️🧠🧪 Next on the Horizon: Frederik Ceyssens from ReVision Implant on scaling bionic vision to the cortex with Occular, a high-res, deep-brain prosthesis.

Why performance might beat invasiveness - and what comes next:
www.bionic-vision.org/research-spo...

#BionicVision #NeuroTech #BCI

bionic-vision.org | Research Spotlights | Frederik Ceyssens, ReVision Implant

Frederik Ceyssens is Co-Founder and CEO of ReVision Implant, the company behind Occular: a next-generation cortical prosthesis designed to restore both central and peripheral vision through ultra-flex...

www.bionic-vision.org

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Reposted by Bionic Vision Lab

Michael Beyeler @mbeyeler.bsky.social · May 20

Last but not least is Lily Turkstra, whose poster is assessing the efficacy of visual augmentations for high-stress navigation:

Tue, 2:45 - 6:45pm, Pavilion: Poster #56.472
www.visionsciences.org/presentation...

👁️🧪 #XR #VirtualReality #Unity3D #VSS2025

VSS PresentationPresentation – Vision Sciences Society

www.visionsciences.org

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Reposted by Bionic Vision Lab

Michael Beyeler @mbeyeler.bsky.social · May 18

Coming up: Jacob Granley on whether V1 maintains working memory via spiking activity. Prior evidence from fMRI and LFPs - now, rare intracortical recordings in a blind human offer a chance to test it directly. 👁️ #VSS2025

🕥 Sun 10:45pm · Talk Room 1
🧠 www.visionsciences.org/presentation...

Schematic illustrating the phosphenes elicited by an intracortical prosthesis. A 96-channel Utah array is shown, stimulated with biphasic pulse trains. An arrow points to drawings of visual percepts elicited by electrical stimulation

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Reposted by Bionic Vision Lab

Michael Beyeler @mbeyeler.bsky.social · May 16

Our @bionicvisionlab.org is at #VSS2025 with 2 talks and a poster!

First up is PhD Candidate Byron A. Johnson:

Fri, 4:30pm, Talk Room 1: Differential Effects of Peripheral and Central Vision Loss on Scene Perception and Eye Movement Patterns

www.visionsciences.org/presentation...

Example stimulus from Byron's image dataset: an unobscured version (left) depicting a man on a bike approaching a woman trying to cross the bike lane; a simulation of peripheral vision loss (center), where the woman is clearly visible but the man on the bike is obscured; and a simulation of central vision loss (right), where the man on the bike is apparent but the woman is obscured

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Reposted by Bionic Vision Lab

Michael Beyeler @mbeyeler.bsky.social · Apr 17

Not usually one to post personal pics, but let’s take a break from doomscrolling, yeah?

Some joyful moments from the Plous Award Ceremony: Honored to give the lecture, receive the framed award & celebrate with the people who made it all possible!

@bionicvisionlab.org @ucsantabarbara.bsky.social

Michael Beyeler smiles while receiving the framed Plous Award at UC Santa Barbara. College of Letters & Science's Dean Shelly Gable presents the award in front of a slide thanking collaborators and funders, with photos of colleagues and logos from NIH and the Institute for Collaborative Biotechnologies. The audience watches the moment from their seats.

The lecture hall of Mosher Alumni House is packed as Prof. Beyeler gets started with his lecture titled "Learning to See Again: Building a Smarter Bionic Eye"

Michael Beyeler stands with members of the Bionic Vision Lab in front of a congratulatory banner celebrating his 2024–25 UCSB Plous Award. Everyone is smiling, with some holding drinks, and Michael is holding his young son. The group is gathered outdoors under string lights, with tall eucalyptus trees in the background.

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The Robert Mehrabian College of Engineering @ucsbengineering.bsky.social · Apr 11

Check out his talk, "Learning to See Again: Building a Smarter Bionic Eye," on Monday, April 14th, 4pm-6pm at Mosher Alumni House.💡

For more info click here: www.campuscalendar.ucsb.edu/event/beyele...

Michael Beyeler | 2024-2025 Plous Award Lecture

"Learning to See Again: Building a Smarter Bionic Eye" What does it mean to see with a bionic eye? While modern visual prosthetics can generate flashes of light, they don’t yet restore natural…

www.campuscalendar.ucsb.edu

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Reposted by Bionic Vision Lab

The Robert Mehrabian College of Engineering @ucsbengineering.bsky.social · Apr 11

Modern visual prosthetics can generate flashes of light but don’t restore natural vision. What might bionic vision look like?

In CS asst. prof Michael Beyeler's @bionicvisionlab.org his team explores how smarter, more adaptive tech could move toward a bionic eye that's functional & usable.👁️

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Reposted by Bionic Vision Lab

bionic-vision.org @bionic-vision.org · Jan 23

Virtual Human Retina: A simulation platform designed for studying human retinal degeneration and optimizing stimulation strategies for retinal implants 👁️🧠🧪

doi.org/10.1016/j.br...

Examples of discrete neuronal network models of the human retina, including the central (top) and peripheral retina (bottom). Photoreceptors, bipolar cells, and ganglion cells are shown.

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Bionic Vision Lab @bionicvisionlab.org · Dec 17

“Seeing the future”: More media coverage about @mbeyeler.bsky.social winning the 2024-25 Harold J. Plous Memorial Award @ucsantabarbara.bsky.social

news.ucsb.edu/2024/021709/...

Seeing the future: Michael Beyeler’s work in neurotechnology earns him top faculty award

Recognized for outstanding contributions in research, teaching and service, as well as “his dedication to innovation, excellence and student success," the researcher behind the "bionic eye" receives o...

news.ucsb.edu

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Bionic Vision Lab @bionicvisionlab.org · Dec 13

Our PI @mbeyeler.bsky.social has received the 2024-’25 Harold J. Plous Memorial Award by @ucsb.bsky.social, in recognition of his “outstanding contributions in research, teaching, and service.“

New article by @ucsbengineering.bsky.social:
engineering.ucsb.edu/news/outstan...

Outstanding Contributions

Assistant professor Michael Beyeler is selected for the highly regarded Harold J. Plous Memorial Award.

engineering.ucsb.edu

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Reposted by Bionic Vision Lab

David A. Markowitz @davidamarkowitz.bsky.social · Dec 2

Please share: ARIA is offering £500k seed awards for neural interface projects. Apply by 13 Feb 2025.

I've been impressed with ARIA's scientific team and overall execution so far. They deserve your best ideas!

www.aria.org.uk/scalable-neu...

Scalable Neural Interfaces – Opportunity seeds - ARIA

To support scientific and technological breakthroughs, outside of programmes, ARIA Programme Directors can award opportunity seeds to support ambitious research aligned to the opportunity spaces they’...

www.aria.org.uk

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Reposted by Bionic Vision Lab

Max Hodak @maxhodak.bsky.social · Nov 23

I had an idea way back in college which I've long thought could be, in many ways, the ultimate BCI technology. What if instead of using electrodes, we used biological neurons embedded in electronics to communicate with the brain?

Enter biohybrid neural interfaces: science.xyz/news/biohybr...

Biohybrid neural interfaces: an old idea enabling a completely new space of possibilities | Science Corporation

Science Corporation is a clinical-stage medical technology company.

science.xyz

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