Hossein Borhan
borhan-aafc.bsky.social
Hossein Borhan
@borhan-aafc.bsky.social
Molecular plant pathology research scientist at Agriculture and Agri-Food Canada
Reposted by Hossein Borhan
Designing synthetic regulatory elements using the generative AI framework DNA-Diffusion www.nature.com/articles/s4...
December 27, 2025 at 3:15 PM
Reposted by Hossein Borhan
Reposted by Hossein Borhan
Reposted by Hossein Borhan
Congrats to #BioEGSB affiliate scientist Ben Rubin and team on publication of @therubinlab.bsky.social's first lead paper!
New in Nucleic Acids Research from the Rubin Lab — OriGen, a language model that can generate plasmid origins of replication. 🔄🦠 The model makes sequences that are remarkably different from wild type origins, yet still replicate in vivo. Read here: https://ow.ly/jjOt50XIBxb
December 19, 2025 at 6:35 PM
Reposted by Hossein Borhan
A twice-weekly cocktail of three messenger RNAs can rejuvenate the weary immune systems of aged mice and boost responses to vaccination and cancer treatments

go.nature.com/4j6lwAn
Restoring youth to old immune cells: mRNA therapy turns back the clock.
Testing in mice suggests that rejuvenating T cells could make vaccines and some cancer therapies more effective.
go.nature.com
December 17, 2025 at 4:52 PM
Reposted by Hossein Borhan
Another exciting preprint! Two additional HMA-TKP sensors from wheat and barley, swapping HMAs can confer recognition specificity. Evo analyses supporting HMA-TKP has differentiated to recognize different effectors through HMA diversification. other links below. www.biorxiv.org/content/10.6...
Evolution of HMA-integrated tandem kinases accompanied by expansion of target pathogens
Tandem kinase proteins (TKPs) are an emerging family of plant intracellular immune receptors that offer potential for developing novel disease resistance. We cloned Rmo2 and Rwt7, genes for resistance...
www.biorxiv.org
December 17, 2025 at 6:25 PM
Reposted by Hossein Borhan
Want to establish your research program in Canada?
The Canada Impact+ Research Chairs (Impact+) program is designed to support institutions in attracting world-leading researchers whose work addresses critical national and global challenges.

www.canada.ca/en/impact-pl...
Application process - Canada.ca
www.canada.ca
December 12, 2025 at 8:21 PM
Reposted by Hossein Borhan
Nature research paper: Fasting boosts breast cancer therapy efficacy via glucocorticoid activation

go.nature.com/48yFe44
Fasting boosts breast cancer therapy efficacy via glucocorticoid activation - Nature
Beneficial effects of fasting combined with endocrine therapy for oestrogen receptor-α-expressing breast cancers can be recapitulated using exogenous glucocorticoid receptor ligands instead of fasting to reduce harmful effects.
go.nature.com
December 10, 2025 at 5:45 PM
Reposted by Hossein Borhan
Canada lost its official measles elimination status after a year of continuous transmission
The Americas Are No Longer Officially Measles-Free
Canada lost its official measles elimination status after a year of continuous transmission
www.scientificamerican.com
November 10, 2025 at 11:09 PM
Reposted by Hossein Borhan
The number of low-quality or fraudulent publications is rising to hundreds of thousands per year. It is time to reevaluate current publishing models and outline a global plan. Read the 'Reformation of science publishing: the Stockholm Declaration': royalsocietypublishing.org/doi/10.1098/... #RSOS 🧪
November 11, 2025 at 8:35 AM
Reposted by Hossein Borhan
Reposted by Hossein Borhan
A new technique called ‘mind captioning’ generates descriptive sentences of what a person is seeing or picturing in their mind using a read-out of their brain activity, with impressive accuracy.

go.nature.com/3XbnxB1
‘Mind-captioning’ AI decodes brain activity to turn thoughts into text
A non-invasive imaging technique can translate scenes in your head into sentences. It could help to reveal how the brain interprets the world.
go.nature.com
November 5, 2025 at 8:17 PM
Reposted by Hossein Borhan
By studying the process through which a soil bacterium naturally produces a well-known drug, scientists have discovered a powerful antibiotic that could help to fight drug-resistant infections

go.nature.com/4oQ8bxO
Powerful new antibiotic that can kill superbugs discovered in soil bacteria
Surprise discovery could pave the way for new treatments against drug-resistant infections.
go.nature.com
October 31, 2025 at 5:17 PM
Reposted by Hossein Borhan
German researchers team up with Danish biotech @novonesis.com to find a solution to one of the ocean’s biggest plastic polluters: a bacterium that eats the recalcitrant polyamides in discarded fishing nets nature.com/articles/s41...
rdcu.be/eL3j1
Ghost fishing nets meet microbial recyclers - Nature Biotechnology
Nature Biotechnology - Ghost fishing nets meet microbial recyclers
nature.com
October 21, 2025 at 6:26 PM
Reposted by Hossein Borhan
Membrane contact sites between chloroplasts and the pathogen interface underpin plant focal immune responses (Enoch Lok Him Yuen, Zachary Savage, Vojtěch Pražák, et al) doi.org/10.1093/plce... #PlantScience
Membrane contact sites between chloroplasts and the pathogen interface underpin plant focal immune responses
Chloroplast tethering to the pathogen interface via membrane contact sites promotes focal callose deposition and strengthens plant immunity.
doi.org
October 16, 2025 at 6:08 PM
Reposted by Hossein Borhan
Jane Goodall, known for her pioneering work with chimpanzees, has passed away aged 91

go.nature.com/46QHIZk
Jane Goodall’s legacy: three ways she changed science
Nature - The primatologist challenged what it meant to be a scientist.
go.nature.com
October 4, 2025 at 1:19 PM