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brianrepko.hachyderm.io.ap.brid.gy
@brianrepko.hachyderm.io.ap.brid.gy
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Here's the second entry in a series of blog posts on the #cdisc Dataset-JSON standard. This entry goes over potential issues with the specification.

Pushing for the future of #clinicaltrial #data (and related to the #pharmaverse and #rstats folks in #Biomedicalresearch).

Here's to moving past […]
Original post on hachyderm.io
hachyderm.io
January 16, 2026 at 7:25 PM
Reposted by brianrepko.hachyderm.io.ap.brid.gy
missingthept.bsky.social
New ICE Bucket Challenge just dropped.
Nick Sortor @nicksortor BREAKING: Rioters are now pouring BUCKETS OF WATER right outside the driveway of ICE Minneapolis in order to make agents SLIP AND FALL when they're attempting to make arrests This is DISGUSTING. These degenerates are getting away with WAY too much. FRONTLINES 0:53 From FRONTLINES TPUSA 2K 3.6K 13K 401K
January 16, 2026 at 12:59 AM
Reposted by brianrepko.hachyderm.io.ap.brid.gy
electrafish.social.electrafish.tech.ap.brid.gy
Rebellions Are Built on 'Ope

Credit: https://www.reddit.com/r/andor/s/tKpF9uA3NT

#hope #minneapolis #mpls #msp #Minnesota #mn #mnastodon #StarWars #Andor #rebellion #fascism #trump
Yellow writing on purple image of the state of Minnesota with the Star Wars Rebel Alliance symbol: Rebellions are built on 'Ope
January 16, 2026 at 1:36 AM
hey #quarto folks - is there an easy way to append {target="_blank"} to all my URLs?
January 15, 2026 at 5:45 PM
Reposted by brianrepko.hachyderm.io.ap.brid.gy
anneapplebaum.bsky.social
And here we are: the entire transatlantic alliance is now talking about Greenland, instead of talking about ending the war in Ukraine.
January 14, 2026 at 1:36 PM
RE: https://hachyderm.io/@alter_kaker/115891326411527717

And Indivisible, ISAIAH, 50501, Women’s March….

General strike on Jan 23 - march in downtown Mpls
alter-kaker.hachyderm.io.ap.brid.gy Marc Trius @alter-kaker.hachyderm.io.ap.brid.gy · 4d
Not your social media "general strike"

"Major labor unions in #minnesota are supporting the call, including Amalgamated Transit Union (ATU) Local 1005, SEIU Local 26, UNITE HERE Local 17, CWA Local 7250, and St. Paul Federation of Educators Local 28 — and organizers expect this list to grow." […]
Original post on hachyderm.io
hachyderm.io
January 14, 2026 at 11:28 AM
Here’s how #minnesota is responding to ICE in our neighborhoods and the murder of Ms. Good. From ISAIAH MN.

https://docs.google.com/document/u/0/d/1_glfqFDoPCLK3MdaK7Xxb01TzQdcKtAZFqOkk4K8qIA/mobilebasic?pli=1
January 9, 2026 at 3:33 AM
We (US) took Denmark’s child vaccination schedule - can we also take their immigration policies and enforcement mechanisms? Having been an immigrant in both the UK and Switzerland, what we do in the US is barbaric.
January 8, 2026 at 3:30 PM
Reposted by brianrepko.hachyderm.io.ap.brid.gy
sarahjeong.bsky.social
The sheer number of videos of the shooting is horrific, but in the vein of what @prisonculture.bsky.social has been saying, it proves how many people cared enough to show up where ICE was and record them. It wasn't just one or two legal observers, and when Good was shot, they didn't abandon her.
January 8, 2026 at 12:19 AM
Reposted by brianrepko.hachyderm.io.ap.brid.gy
free-press.mstdn.social.ap.brid.gy
BREAKING NEWS 🚨🚨🚨

Reports of Dozens of US helicopters dropping American paratroopers into Caracas, Venezuela!
#aurefreepress #News #press #headline #gop #Politics #uspolitics #USpol #Breaking #breakingnews #Trump #mastodonnews
January 3, 2026 at 6:45 AM
Reposted by brianrepko.hachyderm.io.ap.brid.gy
assignedmale.bsky.social
The best of 2025 : Accountabiility.
4 frame comic. a street reporter approaches a man wearing a big hoodie, asking : sir! how much do you think we should hold feminism accountable for the male loneliness epidemic? he replies : there is no meaningful difference between the rates of loneliness between men and women*. the reason we're always talking about men's is that they're making it everyone else's problem. A note under the frame adds : *in fact, several studies (graham & ong, 2024; cigna & morning consult, 2021) suggest that more women experience loneliness than men. In the 3rd frame, he says : according to research*, the primary reason that men isolate themselves is because they feel incapable of living up to rigid gendered expectations. the far-right exploits that vulnerability to radicalize young men. another note under the frame adds a source : *the state of american men 2025, equimundo: center for masculinities and social justice. fourth frame : If anything, feminism is the solution to men's loneliness. let's deconstruct the gender norms that hurt everyone, before these techno-fascists divide us even more.
January 1, 2026 at 6:54 PM
First entry in a series of blog posts on the #cdisc Dataset-JSON standard. Diving in on the future of #clinical #research #data (and related to the #pharmaverse and #rstats folks in #Biomedicalresearch)

https://brianrepko.github.io/blog/posts/2025-12-31-datasetjson-part1/
Dataset-JSON – Learning, Thinking, and Coding
Part 1 - intro to the series
brianrepko.github.io
January 1, 2026 at 8:53 PM
Reposted by brianrepko.hachyderm.io.ap.brid.gy
mmasnick.bsky.social
Ok. Now had a chance to check and, well, at least some docs do appear to be straight up classic redaction fail. And there are some *interesting* bits here.

www.justice.gov/multimedia/C...
Showing highlights of paragraphs 202 through 206 in a doc with 203-205 blacked out. Text in next image 202. Defendants also actively obstructed law enforcement by denying investigators access to Little St. James beyond its boat dock. 203. Defendants also attempted to conceal their criminal sex trafficking and abuse conduct by paying large sums of money to participant-witnesses, including by paying for their attorneys’ fees and case costs in litigation related to this conduct. 204. Epstein also threatened harm to victims and helped release damaging stories about them to damage their credibility when they tried to go public with their stories of being trafficked and sexually abused. 205. Epstein also instructed one or more Epstein Enterprise participant-witnesses to destroy evidence relevant to ongoing court proceedings involving Defendants’ criminal sex trafficking and abuse conduct. 206. Defendants also concealed their fraud on the Government in obtaining unearned tax benefits by providing false testimony and submitting false and inaccurate reporting to the Economic Development Commission to prevent detection of Defendant Southern Trust Company’s non-compliance with requirements concerning the nature of its business and the residency of the persons it employed.
December 23, 2025 at 4:10 AM
New blog post on #tiledb and #snowflake integration and what is possible for #biomedical #research and what I wish I could do in #duckdb

https://brianrepko.github.io/blog/posts/2025-12-20-tiledb-snowflake/
TileDB and Snowflake integration – Learning, Thinking, and Coding
Webinar on data integration
brianrepko.github.io
December 20, 2025 at 8:28 PM
RE: https://hachyderm.io/@brianrepko/115747470507287929

And here is the inspiring keynote - https://www.youtube.com/watch?v=-1UeDfTk8HI
 brianrepko.hachyderm.io.ap.brid.gy @brianrepko.hachyderm.io.ap.brid.gy · Dec 19
Here in #minnesota, on Dec 13th, there was a gathering of over 5000 people of all faiths (ISAIAH) to put forth an agenda we can advocate for with our various political parties - The People’s Agenda: Dignity and Affordability for All - https://bit.ly/PeoplesAgenda2026

The Christian coalition was […]
Original post on hachyderm.io
hachyderm.io
December 20, 2025 at 7:27 PM
Reposted by brianrepko.hachyderm.io.ap.brid.gy
cdarwin.c.im.ap.brid.gy
HUGE NEWS from the new Epstein files:

Records show that Maria Farmer, who worked for Epstein, filed a "child pornography" report to the FBI in 1996.

The FBI has never before acknowledged that complaint. The case went nowhere, and mass abuse followed […]
Original post on c.im
c.im
December 20, 2025 at 1:11 AM
Here in #minnesota, on Dec 13th, there was a gathering of over 5000 people of all faiths (ISAIAH) to put forth an agenda we can advocate for with our various political parties - The People’s Agenda: Dignity and Affordability for All - https://bit.ly/PeoplesAgenda2026

The Christian coalition was […]
Original post on hachyderm.io
hachyderm.io
December 19, 2025 at 5:47 PM
US tech (#software) companies used to hire and train and you could grow your experience with them. That was my experience of the 90s. Then it became hiring only those with experience - training really fell off - if lucky you could go to the big firms for those first jobs. Now, this feels like […]
Original post on hachyderm.io
hachyderm.io
December 19, 2025 at 5:26 PM
Reposted by brianrepko.hachyderm.io.ap.brid.gy
moira.mastodon.murkworks.net.ap.brid.gy
This is from a few hours ago but:

https://www.seattletimes.com/seattle-news/weather/catastrophic-flooding-expected-in-king-snohomish-skagit-counties/

If the link doesn't work here's the map.

#seattle #flood #floods #flooding #WashingtonState #wawx #cascadia
A map showing "catastrophic" national weather centre flood hazard outlook following mostly the watersheds of the Snohomish, Stillaguamish and Skagit rivers in King, Snohomish, and Skagit counties. Area outside that show anywhere from "limited" to "considerable" flood potential.
December 12, 2025 at 1:02 AM
RE: https://mastodon.social/@rstatsblazeemail/115685976251613412

For #clinicaltrials and #rstats - this is a big deal - CSRs (Module 5 in an eCTD) can now contain R packages within zip files (and html files - for WASM/Shiny?) and it looks like binary R package files for Modeling and Simulation […]
Original post on hachyderm.io
hachyderm.io
December 10, 2025 at 5:07 PM
Reposted by brianrepko.hachyderm.io.ap.brid.gy
joeinwynnewood.mstdn.social.ap.brid.gy
This is what every police chief in America should be saying and enforcing.

Minneapolis police chief warns officers: Stop unlawful force by ICE or lose your job
https://www.ms.now/news/minneapolis-police-chief-unlawful-force-ice-jobs
Minneapolis police chief warns officers: Stop unlawful force by ICE or lose your job
Chief Brian O’Hara says he’ll fire city police officers if they don’t intervene when immigration agents use unlawful force. The post Minneapolis police chief warns officers: Stop unlawful force by ICE or lose your job appeared first on MS NOW.
www.ms.now
December 6, 2025 at 1:03 AM
I know #FrankGehry is dead (RIP) but everyone of his buildings that I’ve lived near - all northern climates - require mediation of falling snow and ice - typically closed sidewalks. Just don’t get that that is “great” architecture.
December 6, 2025 at 3:38 PM
TIL about the Open Source Pledge - https://opensourcepledge.com - based on @Posit posting on their 2025 status on their pledge commitment - https://posit.co/blog/posit-open-source-pledge-2025/

Highly recommend sharing this internally at companies - particularly those with $$$. I'd really like […]
Original post on hachyderm.io
hachyderm.io
December 4, 2025 at 5:30 PM
Reposted by brianrepko.hachyderm.io.ap.brid.gy
reillypascal.hachyderm.io.ap.brid.gy
I just realized the current stable version of Python is 3.14.1, which makes it Pi-thon
December 4, 2025 at 12:08 AM