Artur Vetkas
@ca1ca2ca3ca4.bsky.social
These results show the potential for fMRI-guided, personalized SCS programming - moving beyond trial-and-error approaches toward precision neuromodulation, and highlight the complexity of central mechanisms in chronic pain.
January 18, 2025 at 5:49 PM
These results show the potential for fMRI-guided, personalized SCS programming - moving beyond trial-and-error approaches toward precision neuromodulation, and highlight the complexity of central mechanisms in chronic pain.
Optimal SCS enhances PAG and midbrain activity while reducing signals in emotional/cognitive hubs like the ACC and insula. On a network level it strengthens descending pain inhibition and modulates affective/cognitive pain pathways for effective analgesia. (3/4)
January 18, 2025 at 5:49 PM
Optimal SCS enhances PAG and midbrain activity while reducing signals in emotional/cognitive hubs like the ACC and insula. On a network level it strengthens descending pain inhibition and modulates affective/cognitive pain pathways for effective analgesia. (3/4)
We saw that paresthesia-free or low-frequency (40 Hz) stimulation augments prefrontal engagement, while high-frequency (1200 Hz) modulates sensorimotor cortices. (2/4)
January 18, 2025 at 5:49 PM
We saw that paresthesia-free or low-frequency (40 Hz) stimulation augments prefrontal engagement, while high-frequency (1200 Hz) modulates sensorimotor cortices. (2/4)