Penicillin Susceptible Staphylococcus aureus IS REAL!

"this is all just part of my CPD record"

Seems like a good catchphrase

Was looking for this content and couldn't find it. I'm newly covering maxfax and ENT areas - couldn't see that much content. Any recommendations on conferences for these?

An example of a commercially available system below.

Strikes me that locally we have all this data but due to different systems there is no way to view as overview and so need to spend time creating summaries.

Consequence of digitised systems rather than digital transformation of care?

There was more covered. Great session!

5. Update on enterococcal breakpoints. Including other species

Remember intrinsic vanc resistance ones! Cassesiflavus and gallinarum

Update on upcoming new anaerobic breakpoints - exciting but methodology difficult and so likely ref lab still

4. Answers to questions about dosing: Generally to use breakpoints table. But in IE breakpoints refer to ESC guidelines. Also rationale for no I category and assumption that highest dose always used

This seems less useful (to me) given issues in ESC dosing tables and clinical data on oral switch.

3. Breakpoints for cefepime-enmetazobactam (always a pleasure to try to spell) and aztreonam-avibactam

2. Stenotrophomonas updated breakpoints:
Updates CoT R breakpoint. ECOFFS for other agents. And a nice bonus on mechanisms of beta lactams resistance

I'm now not so sure about HECK Yes. Patrick Harris was suggesting we should be more reluctant to switch from piptaz etc to mero based on risk of ampC unless Enterobacter.

Will be interesting to see next ESCMID DTR GN guidelines and IDSA 2025 on AmpC.

But for purposes of teaching, yes - HECK yes!

Interesting chart. Some doubt about oral beta lactams for bacteraemia oral switch given time/MIC concerns and not meeting PD target in Enterobacterales with higher MICs. Was this addressed at all? Perhaps need an organism/MIC specific approach?

It is so complex but Patrick Harris's talk key - clinical data (so far) shows mostly need to worry about Enterobacter CC. So I will watch with interest but likely not teach on till we have more clinical!