Our findings suggest a hierarchical model of sensory processing, where sensory cortices act as continuous input providers while the entry stage of the hippocampus, the dentate gyrus, acts as an on-off-switch for task relevance.

We computed decoding chance level by randomly shuffling laps labels. This revealed that the visual cortex maintained a high sensory discrimination regardless of behavioural engagement, whereas the dentate gyrus required active navigation for effective discrimination.

We employed the CEBRA method for latent embeddings, and built a binary decoder trained to predict which environment was being explored based solely on neuronal activity.

During each session, either two very distinct environments were alternating at random (A-B) or two more similar corridors (A-A’). Animal received a reward when stopping long enough within an uncued location. This location was different in environment A and A’/B, forcing the animal to discriminate.

We used 2-photon imaging to record mice navigating in virtual-reality.
🎮 During active navigation, their position along the track was controlled by the distance run on the wheel.
📺 In passive exposure, instead of converting speed into a position, we broadcasted a replay from another session.

The main project from my PhD, in collaboration with Manuela Allegra and @schlab.bsky.social is now available as a preprint! We wondered how the hippocampus and the visual cortex may differ in the way they refine sensory inputs into internal representations

Well deserved! Congrats!

🌍🧠 💤Join us on June 20th, 2025, in Oslo for a workshop that bridges System Neuroscience and Sleep Research in partnership with @esrs.bsky.social @ncmbm.bsky.social @sainsburywellcome.bsky.social @uio.no @KU
A satellite of the FENS regional meeting, register here:
frm2025oslo.no/basic-sleep-...

The scenes in the Oval Office today will shame the US for decades. They’ll never be forgotten.

A world leader, fighting for his country against the 21st century’s Nazis, came to the US and was attacked & abused by a gangster regime siding with the fascist invaders.

A historic disgrace.

I completely forgot to mention it here, but I actually defended my PhD last fall! And I recently started as a postdoctoral fellow in Oslo, in @charlotteboccara.bsky.social group. Back to the Scandinavian weather ☃️.

Our new study is out on BioRXiv!

tinyurl.com/pfcmap

We (@carlenlab.bsky.social lab) mapped the mouse PFC using single-unit activity! We recorded ~23,000 neurons across cortical/subcortical regions and profiled spont. firing patterns to reveal what separates the PFC from other brain regions.

1/n

After a few days on Bluesky, I'm not sure what I miss most about Twitter. Weird Ai-generated ads? Sex bots offering nudes? The app not working while my phone is charging? The imbecile owner being praised as a genius? Anyway, hello everyone! I'll try to be slightly more active here, hopefully.

Having such a cute doggo to showcase feels like cheating!