Pearson Lab
@capearson.bsky.social
1.4K followers
1.5K following
41 posts
Developmental Neurobiology | Autism | Epilepsy | Cortex | Neural stem cells | mouse | human
Assistant Professor Weill Cornell Medicine.
UCLA, University of Sheffield, University of Newcastle upon Tyne alum
capearsonlab.com
(Posts my own opinions)
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Reposted by Pearson Lab
Pearson Lab
@capearson.bsky.social
· Sep 7
Pearson Lab
@capearson.bsky.social
· Sep 7
Mitochondrial dysfunction precedes neurodegeneration in DRPLA patient-derived neurons, and phenylbutyrate improves survival.
Dentatorubral-pallidoluysian atrophy (DRPLA) is a progressive autosomal-dominant neurodegenerative disorder caused by a CAG repeat expansion in the ATN1 gene, which encodes the transcriptional corepre...
www.biorxiv.org
Pearson Lab
@capearson.bsky.social
· Aug 7
Pearson Lab
@capearson.bsky.social
· Jun 21
Pearson Lab
@capearson.bsky.social
· Jun 7
Pearson Lab
@capearson.bsky.social
· Apr 21
Cryopreservation of Human Cortical Organoids Using Vitrification
Cryopreservation at ultra-low temperatures is a valuable tool for preserving cells and tissues used in research. However, few protocols exist for the preservation of brain organoid models. Current met...
www.biorxiv.org
Pearson Lab
@capearson.bsky.social
· Apr 9
Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN
Dr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...
www.cnn.com
Pearson Lab
@capearson.bsky.social
· Mar 11
Metabolic Atlas of Early Human Cortex Identifies Regulators of Cell Fate Transitions
Characterization of cell type emergence during human cortical development, which enables unique human cognition, has focused primarily on anatomical and transcriptional characterizations. Metabolic pr...
www.biorxiv.org
Pearson Lab
@capearson.bsky.social
· Mar 8
Pearson Lab
@capearson.bsky.social
· Mar 8
Pearson Lab
@capearson.bsky.social
· Mar 8
Cell-type-specific roles of FOXP1 in the excitatory neuronal lineage during early neocortical murine development
Ortiz et al. leverage mice with loss of FOXP1 in their cortical progenitors. Detailed
cell-type-specific genomic and epigenetic alterations are described, with key findings
in progenitors related to a...
www.cell.com
Reposted by Pearson Lab
Pearson Lab
@capearson.bsky.social
· Dec 11
Pearson Lab
@capearson.bsky.social
· Dec 11