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Carmen Sandi

@carmensandi10.bsky.social

2.8K followers 770 following 50 posts

Professor of Neuroscience @EPFL Brain Mind Institute in Lausanne (Switzerland) #mitochondria #motivation #anxiety #stress @NeuroLeman @StressnetworkC @network_alba She/her ORCID: 0000-0001-7713-8321

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Carmen Sandi @carmensandi10.bsky.social · Feb 19

New lab paper! We reveal a novel mitochondria–cilia interaction in neurons & #mitochondrial control of #ciliary molecular pathways & structure

Kudos to Dogukan Ulgen & Ale Chioino
🙏 O Zanoletti, A Quintana, E Sanz
@epfl-brainmind.bsky.social @jphysiol.bsky.social
Read doi.org/10.1113/JP28...

Mitochondrial control of ciliary gene expression and structure in striatal neurons

Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sens...

doi.org

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Carmen Sandi @carmensandi10.bsky.social · 1d

Here EPFL press release: actu.epfl.ch/news/a-molec...

A molecule repairs brain mitochondria and reverses anxiety in rats

A study led by EPFL shows that Urolithin A, a natural compound, can abolish high anxiety in rats by repairing mitochondrial function in their brain cells, specifically in the nucleus accumbens. The fi...

actu.epfl.ch

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Carmen Sandi @carmensandi10.bsky.social · 1d

Very happy to share our new paper in Biological Psychiatry, showing that Urolithin A reverses high anxiety by repairing mitochondrial function in the nucleus accumbens.

Big kudos to first co-authors David Mallet & Doğukan Ülgen, our amazing team, and collaborators!

🔗 Paper: doi.org/10.1016/j.bi...

Redirecting

doi.org

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Reposted by Carmen Sandi

Johanna Joyce @johannajoyce.bsky.social · 6d

Dr. Jane Goodall, 1934-2025

An exceptional scientist, and a singular woman in science

#WomeninScience 🐒

www.nytimes.com/2025/10/01/o...

Jane Goodall, Eminent Primatologist Who Chronicled the Lives of Chimps, Dies at 91

www.nytimes.com

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Reposted by Carmen Sandi

Lizzie Manning @drlizziemanning.bsky.social · 8d

Time to get working on your symposium proposals!

📣 Roll call
-Who's coming to Cape town?
-Who needs speaker suggestions for a panel?
-Who'd like to join a panel (especially trainees!)
@mfendt.bsky.social @dr-stan.bsky.social @nicoleferrara.bsky.social @eelkesnoeren.bsky.social

International Behavioral Neuroscience Society @ibnsconnect.bsky.social · 25d

We are excited to invite all behavioral neuroscientists to the 35th Annual IBNS Meeting at Cape Town, South Africa June 23-27, 2026!

Call for Symposia / Satellite Proposals Deadline: Tuesday, October 28, 2025

More information can be found at ibnsconnect.org/meetings

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Carmen Sandi @carmensandi10.bsky.social · 9d

New paper from the lab on the predictive role of prefrontal cortex metabolites in motivated effortful behavior in humans. Congrats to Arthur Barakat and @nclairis.bsky.social who led the work & to all our collaborators!

Nicolas Clairis @nclairis.bsky.social · 9d

Arthur's main & final PhD paper is finally out! In it, we show that a few metabolites (mainly glutamate, aspartate and lactate) measured at baseline with 1H-MRS in the dmPFC/dACC allow to predict inter-individual differences in the motivation to engage with cognitively effortful tasks! 1/2

Neurometabolic predictors of mental effort in the frontal cortex - Translational Psychiatry

Translational Psychiatry - Neurometabolic predictors of mental effort in the frontal cortex

www.nature.com

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Reposted by Carmen Sandi

Nature Portfolio @natureportfolio.nature.com · 13d

The abstract submission deadline for our three-day conference on brain energy metabolism is Oct. 3! Join experts such as @rioslab.bsky.social and @carmensandi10.bsky.social to share findings and exchange ideas. Learn more: go.nature.com/4p4rqV9 #Neuroskyence #Academicsky #STEMconference

Swipe to meet some of the experts presenting at Brain Energy Metabolism in Health and Disease, Dec. 3-5, KRAUST Campus, Saudi Arabia

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Carmen Sandi @carmensandi10.bsky.social · 18d

A brilliant keynote today by @jfcryan.bsky.social at the EBPS meeting on how the gut shapes behavior, including striking causal evidence for microbiome’s role in social behaviors. A masterclass of body-brain complexity! & with an impressive depth of data and the right dose of humor!

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Carmen Sandi @carmensandi10.bsky.social · 19d

I just had the pleasure of chairing a symposium at the EBPS meeting in Almería on “Endocannabinoids and Sex-dependent Behavior: Insights from Development to Adulthood”

Many thanks to @miriammelis.bsky.social, Olivier Manzoni, Arnau Busquets-Garcia & Silvie Ruigrok for outstanding contributions!

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Carmen Sandi @carmensandi10.bsky.social · 21d

Wonderful to have had you with us for your sabbatical at @epfl-brainmind.bsky.social, @argelaguilarvalles.bsky.social! Many thanks for all the exchanges, your input to our projects and your great talk! & Looking forward to continuing our collaboration!

Argel Aguilar Valles @argelaguilarvalles.bsky.social · 21d

Wrapping up a short sabbatical visit to @carmensandi10.bsky.social's lab at @epfl-brainmind.bsky.social — an inspiring experience supported by the Swiss National Science Foundation @snsf.ch 🙏.

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Carmen Sandi @carmensandi10.bsky.social · 28d

Great Seminar today at @epfl-brainmind.bsky.social with Mootaz Salman (Oxford, UK) @oxforddpag.bsky.social
We learned how blood-brain barrier dysfunction drives neurodegenerative disease & how 3D BBB-on-a-chip models uncover new therapeutic targets
Many thanks for the highly inspiring talk!

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Carmen Sandi @carmensandi10.bsky.social · Sep 3

Excellent opportunity to get a grant to attend the FENS Forum in Barcelona! @fens.org - APPLY!

ALBA Network @network-alba.bsky.social · Sep 2

🧠 Are you an early-career brain science researcher interested to attend #FENS2026 in Barcelona, Europe’s largest #neuroscience meeting? Apply for the ALBA-CHS Travel Awards!

✈️ Tiered grants for EU & non-EU candidates
✅ Final-year PhD/MD or ≤10 years post-PhD/MD
👉🏽 loom.ly/7FOgCJc
📆 21 Oct 2025

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Reposted by Carmen Sandi

EPFL Brain Mind Institute @epfl-brainmind.bsky.social · Aug 26

The group of @epfl-brainmind.bsky.social professor Carmen Sandi @carmensandi10.bsky.social shows Corticotropin-releasing Hormone (CRH) modulates the thalamic reticular nucleus brain region to affect sleep, linking CRH with sleep impairment due to stress and anxiety- www.nature.com/articles/s41...

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Carmen Sandi @carmensandi10.bsky.social · Aug 20

Neuroscientists - Nominate an outstanding colleague for this prize, with opportunity to give a special lecture at the FENS Forum #FENS2026!

ALBA Network @network-alba.bsky.social · Aug 20

📣Call open for the 2026 ALBA-Elsevier Award Lecture! Nominate outstanding neuroscientists who push the frontiers of brain research, champion EDI, & work in underrepresented countries.

🏆Special Lecture at #FENS2026
✅Must have led own lab ≥5 years
👉🏽Check eligibility loom.ly/FEG7E-w
📆15 Oct 2025

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Carmen Sandi @carmensandi10.bsky.social · Aug 20

Happy to announce our new paper in Nature Communications: rdcu.be/eBpGY
We show how CRH in the thalamic reticular nucleus modulates NREM sleep, helping to understand how stress impacts sleep

Congrats to Loredana Cumpana and team, in work led by Simone Astori!
@epfl-brainmind.bsky.social‬

Corticotropin-releasing hormone modulates NREM sleep consolidation through the thalamic reticular nucleus

Nature Communications - Corticotropin-releasing hormone (CRH), known for activating the HPA axis during stress, also acts centrally in the brain. Here, the authors show that CRH modulates thalamic...

rdcu.be

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Reposted by Carmen Sandi

EPFL Brain Mind Institute @epfl-brainmind.bsky.social · Aug 18

The group of @epfl-brainmind.bsky.social Prof. Michael Herzog (also + @carmensandi10.bsky.social) show that human social dominance, a key social interaction factor, is a stable personality trait, has reliable specific brain EEG markers which in females mirror those in males doi.org/10.1016/j.is...

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Reposted by Carmen Sandi

Bita Moghaddam @bita137.bsky.social · Jul 31

New lab paper by @merridee.bsky.social identifying a novel role for VTA GABA neurons in behavioral flexibility

GABA, but not dopamine, neuron activation correlates with behavior when cues unexpectedly shift from predicting punishment to predicting reward www.sciencedirect.com/science/arti...

Flexible updating of reward and punishment contingencies by VTA GABA neurons

In dynamic environments where stimuli predicting reward or punishment unexpectedly change, it is critical to flexibly update behavior while preserving…

www.sciencedirect.com

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Carmen Sandi @carmensandi10.bsky.social · Jul 16

Join us this December at the Nature Conference on Brain Energy Metabolism in Health and Disease, involving researchers from across various disciplines to discuss brain metabolic research and neurological function. go.nature.com/40jh3SM

Brain Energy Metabolism in Health and Disease

This Nature Conference examines how energy metabolism in the brain impacts neurological function and disease. Recent technologies have expanded our understanding of metabolic processes among neurons, ...

go.nature.com

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Reposted by Carmen Sandi

John F. Cryan @jfcryan.bsky.social · Jul 9

Stress is wrecking your health: how can science help?
Better stress assessment and tailored interventions could give clinicians the tools they need to fend off lasting damage.
I enjoyed talking with @lynnepeeps.bsky.social for this article in Nature
www.nature.com/articles/d41...

Stress is wrecking your health: how can science help?

Better stress assessment and tailored interventions could give clinicians the tools they need to fend off lasting damage.

www.nature.com

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Reposted by Carmen Sandi

ebbsociety.bsky.social @ebbsociety.bsky.social · Jun 28

The heat won’t stop the energy — science (and fans!) in full swing!
🔆🪭💪
#EBBS2025

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Reposted by Carmen Sandi

Federation of European Neuroscience Societies - FENS @fens.org · Jul 1

🎧 Tune in today!

Heard of a little thing called the #ALBA-#IBRO Diversity Podcast? If not, it's time you checked it out! 🌟

👉 https://loom.ly/PvDlNOI

@network-alba.bsky.social @ibroorg.bsky.social

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Reposted by Carmen Sandi

Argel Aguilar Valles @argelaguilarvalles.bsky.social · Jun 28

🧠💥 Our new preprint is out!

We pooled 5 RCTs on intranasal esketamine for treatment-resistant depression—and found clear sex-specific patterns in how patients respond.
Read it here: www.medrxiv.org/content/10.1...

#TRD #Esketamine #Neuropsychiatry #OpenScience #MentalHealth

Sex differences in placebo and antidepressant response to intranasal esketamine for treatment-resistant depression: a pooled participant analysis of randomized controlled trials

Background Racemic ketamine and its enantiomer, esketamine, have emerged as fast-acting antidepressant options for individuals with treatment-resistant depression (TRD). Yet, despite growing clinical ...

www.medrxiv.org

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Reposted by Carmen Sandi

Katherine Stiles @katherinestiles.org · Jul 1

Scientists must push back against Trump’s genetic exclusion campaigns

Countering the US president’s divisive misuse of genetics starts with asking the right research questions, says Mareile Kaufmann
@timeshighered.bsky.social · #highered · #academicsky · #trump

Scientists must push back against Trump’s genetic exclusion campaigns

Countering the US president’s divisive misuse of genetics starts with asking the right research questions, says Mareile Kaufmann

www.timeshighereducation.com

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Reposted by Carmen Sandi

Marija Kundakovic @kundakoviclab.bsky.social · Jul 1

Enjoying the gala dinner and the beautiful city of Bordeaux last night, w/ @luisadema.bsky.social @jordanmarrocco.bsky.social @cate-cholamine.bsky.social @bohaceklab.bsky.social @ebbsociety.bsky.social #EBBS2025

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Reposted by Carmen Sandi

Alt-NIHscience4ALL @alt-nihscience4all.altgov.info · Jul 1

#AltPride #AltGov
To close out Pride Month, we are recognizing neuroscientist Ben Barres. Beyond making seminal discoveries related to glial cell function, he was also a staunch advocate for equality in science for both women and the LGBTQIA+ community. 1/n

www.nature.com/articles/d41...

Ben Barres (1954–2017)

Neurobiologist who advocated for gender equality in science.

www.nature.com

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