catug.bio
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𝗧𝗵𝗶𝗻𝗸𝗶𝗻𝗴 𝗼𝗳 𝗴𝗲𝗻𝗲𝗿𝗮𝘁𝗶𝗻𝗴 𝗥𝗡𝗔-𝗟𝗡𝗣?

Encapsulate single and multiple RNAs! mRNA, saRNA, circRNA... 👉🏻 delivered in 8-10 weeks.

📩 Reach out today

🔵 At 𝗖𝗔𝗧𝗨𝗚, we provide custom solutions for #DNA, #RNA, and #LNP projects, supporting academia and industry with formulation, research, and manufacturing
June 26, 2025 at 1:02 PM
𝗛𝗲𝗮𝗱𝗶𝗻𝗴 𝘁𝗼 𝗠𝗶𝗹𝗮𝗻𝗼 𝗳𝗼𝗿 𝗟𝗮𝗯 𝗜𝘁𝗮𝗹𝗶𝗮? 𝗟𝗲𝘁’𝘀 𝗰𝗼𝗻𝗻𝗲𝗰𝘁!

Our colleague Cesare Di Nitto will be on site next week at LAB Italia, ready to discuss #RNA and #LNP innovations.

📅 𝗝𝘂𝗻𝗲 𝟭𝟳–𝟭𝟴
📍 𝗡𝗛 𝗠𝗶𝗹𝗮𝗻𝗼 𝗖𝗼𝗻𝗴𝗿𝗲𝘀𝘀 𝗖𝗲𝗻𝘁𝗿𝗲

If you’re looking for a reliable 𝗥𝗡𝗔 𝗮𝗻𝗱 𝗟𝗡𝗣 𝘀𝘂𝗽𝗽𝗹𝗶𝗲𝗿 𝗼𝗿 𝗖𝗗𝗠𝗢 𝗽𝗮𝗿𝘁𝗻𝗲𝗿, we’d love to meet.
June 12, 2025 at 7:17 AM
🧬🔬Which RNA type is right for your project?

#RNAtherapeutics offers a versatile platform for transient gene expression, gene silencing, and regulation of cellular pathways.

But not all RNAs work the same.

Discover it here: catug.bio/rna-types-rn...
June 5, 2025 at 1:04 PM
𝗬𝗼𝘂'𝗿𝗲 𝗻𝗼𝘁 𝗱𝗲𝘀𝗶𝗴𝗻𝗶𝗻𝗴 𝗺𝗥𝗡𝗔 𝗱𝗲𝗹𝗶𝘃𝗲𝗿𝘆 𝘀𝘆𝘀𝘁𝗲𝗺𝘀. 𝗬𝗼𝘂'𝗿𝗲 𝗱𝗲𝘀𝗶𝗴𝗻𝗶𝗻𝗴 𝗶𝗻𝘁𝗲𝗿𝗮𝗰𝘁𝗶𝗼𝗻𝘀 🧪

MengyaoYu, LixinLin, DezhongZhou and ShuaiLiu highlight a fundamental shift in mRNA delivery: 𝘀𝘁𝗿𝘂𝗰𝘁𝘂𝗿𝗲 𝗮𝗹𝗼𝗻𝗲 𝗶𝘀𝗻’𝘁 𝗲𝗻𝗼𝘂𝗴𝗵, performance depends on how your carriers interact with mRNA and biological systems.
June 3, 2025 at 11:14 AM
💡 𝗛𝗶𝗴𝗵𝗹𝗶𝗴𝗵𝘁𝘀 𝗳𝗿𝗼𝗺 𝗡𝗮𝗻𝗼𝗺𝗲𝗱 𝗘𝘂𝗿𝗼𝗽𝗲𝟮𝟱 (#NME25)

- 𝗟𝗶𝗽𝗶𝗱 𝗻𝗮𝗻𝗼𝗽𝗮𝗿𝘁𝗶𝗰𝗹𝗲𝘀, 𝗻𝗮𝗻𝗼𝗰𝗿𝘆𝘀𝘁𝗮𝗹𝘀, 𝗮𝗻𝗱 𝗽𝗼𝗹𝘆𝗺𝗲𝗿-𝗯𝗮𝘀𝗲𝗱 𝘀𝘆𝘀𝘁𝗲𝗺𝘀 were key topics at the event, with numerous presentations and posters showcasing innovative research focused on precision drug delivery.
June 2, 2025 at 3:57 PM
𝗖𝗔𝗧𝗨𝗚 𝘄𝗲𝗹𝗰𝗼𝗺𝗲𝘀 𝗦𝗶𝗻𝗴𝗮𝗽𝗼𝗿𝗲’𝘀 𝗡𝗔𝗧𝗶 𝘁𝗼 𝗼𝘂𝗿 𝗦𝘂𝘇𝗵𝗼𝘂 𝗳𝗮𝗰𝗶𝗹𝗶𝘁𝗶𝗲𝘀

Last Saturday, we had the pleasure of hosting the Nucleic Acid Therapeutics Initiative (NATi) at CATUG.
May 29, 2025 at 7:42 AM
Efficient and specific delivery of nucleic acids remains a key barrier in oncology, limiting therapeutic efficacy. Claudia Lotter, Megan Anna Stierli, Ramya Deepthi Puligilla, Jörg Huwyler developed 𝗹𝗶𝗽𝗶𝗱 𝗻𝗮𝗻𝗼𝗽𝗮𝗿𝘁𝗶𝗰𝗹𝗲𝘀 (𝗟𝗡𝗣𝘀) 𝗺𝗼𝗱𝗶𝗳𝗶𝗲𝗱 𝘄𝗶𝘁𝗵 𝘁𝘄𝗼 𝘁𝗮𝗿𝗴𝗲𝘁𝘀: 𝘁𝗿𝗮𝘀𝘁𝘂𝘇𝘂𝗺𝗮𝗯 (𝗮𝗻𝘁𝗶-𝗛𝗘𝗥𝟮) 𝗮𝗻𝗱 𝗳𝗼𝗹𝗮𝘁𝗲
May 27, 2025 at 11:07 AM
#NME25 𝗸𝗶𝗰𝗸𝘀 𝗼𝗳𝗳 𝘁𝗼𝗺𝗼𝗿𝗿𝗼𝘄!

Don’t miss our intervention at the event! Cesare Di Nitto will be presenting “𝗔𝗱𝘃𝗮𝗻𝗰𝗶𝗻𝗴 𝗥𝗡𝗔 𝗧𝗵𝗲𝗿𝗮𝗽𝗲𝘂𝘁𝗶𝗰𝘀: 𝗺𝗥𝗡𝗔-𝗟𝗡𝗣 𝗧𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆 𝗳𝗿𝗼𝗺 𝗦𝗔𝗥𝗦-𝗖𝗼𝗩-𝟮 𝗩𝗮𝗰𝗰𝗶𝗻𝗲 𝘁𝗼 𝗜𝗻-𝘃𝗶𝘃𝗼 𝗖𝗲𝗹𝗹 𝗧𝗵𝗲𝗿𝗮𝗽𝘆”, showcasing how #mRNA-#LNP systems are helping reshape the future of #vaccines and #celltherapy.
May 26, 2025 at 11:29 AM
We are back from #ASGCT2025! Here are our takeaways:

• 𝗥𝗡𝗔-𝗟𝗡𝗣 𝘁𝗵𝗲𝗿𝗮𝗽𝗲𝘂𝘁𝗶𝗰𝘀 𝗮𝗿𝗲 𝗴𝗮𝗶𝗻𝗶𝗻𝗴 𝗽𝗼𝗽𝘂𝗹𝗮𝗿𝗶𝘁𝘆, with transient mRNA expression and re-dosing increasingly viewed as effective strategies for precise dosage control and enhanced safety.
May 22, 2025 at 2:52 PM
𝗣𝗹𝗮𝗻𝗻𝗶𝗻𝗴 𝘆𝗼𝘂𝗿 𝗻𝗲𝘅𝘁 #𝗚𝗲𝗻𝗲𝗘𝗱𝗶𝘁𝗶𝗻𝗴 𝗲𝘅𝗽𝗲𝗿𝗶𝗺𝗲𝗻𝘁?

Get high-quality 𝗖𝗮𝘀𝟵 𝗺𝗥𝗡𝗔 and custom 𝘀𝗴𝗥𝗡𝗔 👉🏻 delivered in just a few weeks.

📩 Reach out today: catug.bio/contact?utm_...
May 15, 2025 at 2:07 PM
𝗡𝗼 𝗲𝗱𝗶𝘁𝗶𝗻𝗴 ✂️ 𝗡𝗼 𝘃𝗶𝗿𝗮𝗹 𝘃𝗲𝗰𝘁𝗼𝗿𝘀 🦠 𝗝𝘂𝘀𝘁 𝗺𝗥𝗡𝗔 𝗮𝗻𝗱 𝗟𝗡𝗣𝘀 𝗳𝗼𝗿 𝗲𝗽𝗶𝗴𝗲𝗻𝗲𝘁𝗶𝗰 𝗰𝗼𝗻𝘁𝗿𝗼𝗹

Charles W. O'Donnell, Jeremiah Farelli, Houda Belaghzal , PhD, Justin Chen et al. created hashtag#mRNA that encodes for hashtag#epigenetic controllers, silencing or activating genes by modifying hashtag#chromatin.
May 13, 2025 at 2:23 PM
What is it like to lead a lipid nanoparticles (LNPs) drug delivery platform?

MengFei Sun, Director of Drug Delivery at CATUG, opens the doors to her lab and shares how her team is pushing the boundaries of LNP development.

Read it here: catug.bio/blog/the-lnp...
May 12, 2025 at 2:05 PM
Heading to ASGCT 2025? So are we!

We’re excited to connect with you in New Orleans at this year’s #ASGCT2025 to talk about #RNA, #DNA, and #LNP.

📅 𝗠𝗮𝘆 𝟭𝟯–𝟭𝟳
📍 𝗕𝗼𝗼𝘁𝗵 𝟳𝟱𝟮

Working on #RNAtherapeutics?

Reach out to our team or send us a message here: lnkd.in/dqv6XYPe
May 7, 2025 at 2:28 PM
Working on mRNA therapeutics? Your 5' UTR may be holding you back

Cole J.T. Lewis, Li H. Xie, Shivani Milind Bhandarkar, Yixuan Chen, Carson C. Thoreen, Wendy V. Gilbert from Yale University developed a method, named as DART, to screen over 30,000 human 5' UTRs.
May 6, 2025 at 9:54 AM
Are you ready for the LNP revolution?

#RNAtherapeutics are transforming medicine, offering ways to silence disease-causing genes, express proteins, and modulate biological processes.

But #RNA is fragile. It's unstable, easily degraded, and struggles to enter cells.
May 2, 2025 at 3:29 PM
Are peptides the future of brain-targeted delivery? 🎯

Crossing the blood-brain barrier (BBB) is a major roadblock for RNA therapeutics and gene editing tools. This new review highlights how peptide-functionalized nanoparticles unlock precise, non-invasive delivery to neurons and glial cells.
May 2, 2025 at 8:19 AM
It's #WorldImmunizationWeek!

Let's take this opportunity to summarize the history of #RNAvaccines

Read more here: catug.bio/blog/the-his...
April 24, 2025 at 12:36 PM
Looking for a mRNA supplier? Order off-the-shelf mRNAs or create custom designs here: [link]

🔵 At CATUG, we provide custom solutions for nucleic acid and LNP research, helping academia and industry test new ideas. Discover more here: catug.bio?utm_source=l...
#CATUG #Catpure
April 22, 2025 at 12:16 PM
🧬💡A new study from @Mayo Clinic explores a solution to avoid mRNA-LNP liver expression: leveraging miR-122 binding sites to selectively de-target mRNA expression from the liver.
April 16, 2025 at 2:00 PM
Pre-eclampsia Treatment Using mRNA-LNP 🧬💊
Pre-eclampsia—a life-threatening pregnancy disorder—currently has no approved drug to slow its progression. But what if we could deliver a targeted therapy directly to the placenta? A new study published in Nature unveils a novel LNP platform that does so
April 14, 2025 at 2:00 PM
Overcoming the Mucus Barrier in Cystic Fibrosis 🫁🚧

Delivering gene therapies to CF lungs is tough due to thick mucus and immune defenses.
Soto et al. show peptide-functionalized LNPs can penetrate these barriers and deliver mRNA to lung epithelial cells.

Key insights ⬇️ ⬇️ ⬇️
April 8, 2025 at 2:04 PM
The past decade has been marked by transformative advancements in nucleic acid therapeutics. We are proud to contribute to this field, supporting our collaborators in bringing new treatments to life. Together, we are building a healthier future for all.
April 7, 2025 at 1:11 PM
Breaking the Blood-Brain Barrier with LNPs 🧠⛔️

A study by Han et al. (ACS) shows peptide-functionalized lipid nanoparticles (LNPs) can efficiently deliver mRNA to neurons.

Key insights ⬇️ ⬇️ ⬇️
April 4, 2025 at 2:35 PM
Hello world! This is CATUG!
We provide custom solutions for nucleic acid and LNP research, helping academia and industry test new ideas.
We are happy to become active on this social media 😊
April 3, 2025 at 2:09 PM