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Clinical & Experimental Immunology @ceijournal.bsky.social · 5d

Neuro-Behçet’s disease is a rare but severe manifestation of Behçet’s. This review highlights advances in diagnosis, biomarkers (IL-6, autoantibodies, BAFF), and immunopathogenesis.

🔗 https://bit.ly/4gZDyU0

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Clinical & Experimental Immunology @ceijournal.bsky.social · 5d

🩺 New review highlights immunological insights in liver transplantation from host–graft responses to biomarkers predicting rejection, emphasizing the quest for operational tolerance.

🔗 https://bit.ly/46xnt4l
##LiverTransplant #Immunology

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Clinical & Experimental Immunology @ceijournal.bsky.social · 10d

🔬 New study shows 2B4 (CD244) binds Staphylococcus aureus exotoxin SEB, driving allergic inflammation.

2B4 knockout mice had reduced inflammation → a potential therapeutic target.

Read here: https://bit.ly/4my2B1e
##Immunology #Staphylococcus #Inflammation

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Clinical & Experimental Immunology @ceijournal.bsky.social · 13d

🦴 New study identifies CFI, an NKT cell–related gene, as a promising biomarker in osteoarthritis.

Validated in patients & mouse models, CFI knockdown reduced inflammation.

🔗 https://bit.ly/42Lz1OT
##Osteoarthritis #Biomarkers #Immunology

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Clinical & Experimental Immunology @ceijournal.bsky.social · 20d

Persistent immune activation remains a challenge for people living with #HIV, even with viral control.

On #HIVandAgeing Awareness Day, discover strategies to improve long-term immune health

Read the study here👉 https://bit.ly/4g5VMm4

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Clinical & Experimental Immunology @ceijournal.bsky.social · 23d

A novel Fc-modified anti-haptoglobin mAb shows non-inferior efficacy to IVIG in an ITP monkey model at much lower doses, potentially reducing treatment burden.

Open Access 👉 https://bit.ly/4mN8dWJ

#Immunology #ITP #MonoclonalAntibodies

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Clinical & Experimental Immunology @ceijournal.bsky.social · 26d

Attending the UK inflammation 2025 meeting? #BSIInflammation2025

If your research explores innate immunity & inflammation, consider submitting to Clinical & Experimental Immunology, showcase your work to a global audience!

Learn more🔗 https://bit.ly/443pf8s

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Clinical & Experimental Immunology @ceijournal.bsky.social · 27d

Heading to the UK Inflammation 2025 meeting? #BSIInflammation2025

Check out how sulforaphane targets NLRP3 inflammasomes to relieve inflammation in CP/CPPS, preclinical insights that could inform future therapies.

Read the full study🔗 https://bit.ly/45QNNpI

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Clinical & Experimental Immunology @ceijournal.bsky.social · 28d

HTNV infection impacts CD8+ MAIT cells in HFRS patients, causing both activation and depletion.

These cells show antiviral properties, highlighting a key role in disease defence.

Open Access 👉 https://bit.ly/4g4SoYA

#HFRS #Immunology

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Reposted by Clinical & Experimental Immunology

Waggoner Lab @labwaggoner.bsky.social · Sep 4

CD56 on immune and tumor cells: what is the known and beyond? @ceijournal.bsky.social
academic.oup.com/cei/advance-...

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Clinical & Experimental Immunology @ceijournal.bsky.social · Sep 5

🧠 Altered B-cell subsets and cytokine expression are linked to disease activity in CIDP.

Findings suggest immune signatures could help guide diagnosis and prognosis.

🔗 https://bit.ly/3rzemhN
##CIDP #Neuroimmunology

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Clinical & Experimental Immunology @ceijournal.bsky.social · Sep 3

Alzheimer’s disease is one of the greatest health challenges of our time.

This #WorldAlzheimersMonth, Clinical & Experimental Immunology calls on immunologists investigating Alzheimer’s & immunity to share their findings with us.

Submit here: https://bit.ly/443pf8s

@alzheimerssoc.bsky.social‬

Clinical & Experimental Immunology @ceijournal.bsky.social · Aug 29

💉🌐 Oral vaccines are cheap, easy & life-saving, but why do they underperform in the places they’re needed most?

This paper highlights multifactorial causes & urges tailored solutions for equity in immunisation.

👉 https://bit.ly/42aACy3
##ImmunisationAwarenessMonth

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Clinical & Experimental Immunology @ceijournal.bsky.social · Aug 28

Important insights this #NationalPsoriasisMonth.

🧪 Even with long-term anti-TNF (infliximab) treatment, patients with psoriasis & psoriatic arthritis show immune cell shifts, suggesting ongoing systemic inflammation.

🔗 https://bit.ly/47Ny4sD

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Clinical & Experimental Immunology @ceijournal.bsky.social · Aug 22

IVIG therapy for ITP comes with heavy dose requirements.

A novel Fc-engineered anti-haptoglobin mAb matches IVIG efficacy in primates, at a fraction of the dose.

🔗 https://bit.ly/4mN8dWJ

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Clinical & Experimental Immunology @ceijournal.bsky.social · Aug 20

🧬 Mesoporous silica nanocarriers delivering siRNA against G6PI show promise in rheumatoid arthritis treatment, reducing joint inflammation, FLS proliferation, and tissue damage in a rat model.

Read here: https://bit.ly/4fHxGxI

#Rheumatology #Nanomedicine #Immunology

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Clinical & Experimental Immunology @ceijournal.bsky.social · Aug 19

New study compares mannan vs. imiquimod models of psoriasis in mice. 🧬

Mannan induces more severe, relapsing disease & distinct cytokine profiles, offering a simpler, chronic model for research.

Read here: https://bit.ly/4os9ByU
##NationalPsoriasisMonth #PsoriasisResearch

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Clinical & Experimental Immunology @ceijournal.bsky.social · Aug 16

💉 Checkpoint inhibitors help many melanoma patients, but not all respond. A study finds that TGF-β activity isn’t a reliable predictor, highlighting the complexity of immune resistance. 🧬🛡️

Read the full article here 🔗 https://bit.ly/45zZcc5

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Clinical & Experimental Immunology @ceijournal.bsky.social · Aug 15

Swieboda et al. show that at birth, NK cells & ILCs are already capable of cytokine production, while NKT-like cells are less abundant & functionally immature.

Read the full article🔗 https://bit.ly/3JfJag1

#Immunology

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Clinical & Experimental Immunology @ceijournal.bsky.social · Aug 13

This #CIDP study links reduced naïve/plasma B cells, increased switched memory B cells, and higher IL-6 to worse outcomes, supporting the role of chronic antigen exposure in disease activity.

Read here🔗 https://bit.ly/4lpCE3m

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Clinical & Experimental Immunology @ceijournal.bsky.social · Aug 8

📅 August is National Psoriasis Month 🧬

New research compares mannan vs. imiquimod mouse models, finding mannan triggers stronger, longer-lasting psoriasis-like inflammation and may be a simpler, less harmful way to study chronic disease.

🔗 https://bit.ly/4os9ByU
##immunology

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Clinical & Experimental Immunology @ceijournal.bsky.social · Aug 7

Kromann et al review how intestinal organoids co-cultured with immune cells are advancing our understanding of gut homeostasis, inflammation, infection & cancer. A powerful tool for translational immunology.

📖 https://bit.ly/459Ulzn

#Organoids #Immunology #GutHealth

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Clinical & Experimental Immunology @ceijournal.bsky.social · Aug 5

🤰 Exposure to gestational diabetes mellitus (GDM) leads to subclinical inflammation, driven in part by obesity but also evident in non-obese individuals.

Immune profiling reveals altered NK, T cell, and monocyte populations across metabolic tissues. 👉 https://bit.ly/4okz8dk
##Immunology

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Clinical & Experimental Immunology @ceijournal.bsky.social · Aug 2

From autoimmunity to infectious diseases, if your research bridges basic and clinical immunology, CEI is your home.

With read & publish deals, it's never been easier to go Open Access. 🚀

Learn more: https://bit.ly/4ksUbHJ
##Immunology

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Clinical & Experimental Immunology @ceijournal.bsky.social · Aug 1

🧬 New open access article:

A novel TNFAIP3 variant linked to autoimmunity reveals activation of NF-κB, STAT1 & mTOR pathways, highlighting new mechanisms and potential therapeutic targets in HA20.

🔗 https://bit.ly/4moJffE

#Autoimmunity #Immunology

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