Scott Coyle
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cellraiser.bsky.social
Scott Coyle
@cellraiser.bsky.social
signaling systems and protein circuitry. reimagining what cells can be. fun posts only. Assistant Professor:
@uwbiochem | Postdoc: @stanford @prakashlab | Ph.D.:
@ucsf Wendell Lim @CDI_UCSF
Thanks Claudia ! Full credit to Maggie for making the story so epic in scope. Also: will you be at ASCB this year? Hope to see you again some time soon
December 3, 2025 at 7:31 PM
Thanks Ben! You've set a high bar for protist excellence that continues to inspire and motivate our thinking :)
November 18, 2025 at 5:24 PM
My jaw is still recovering tbh 😂 reconstructive surgery scheduled for next week
November 18, 2025 at 5:22 PM
Finally – there are many mysteries to still resolve for these cells. From dramatic metamorphic capabilities🤯 to prey preference and detection mechanisms 🕵️. For anyone interested in collaborating or getting their hands on these cells, these fantastic beasts culture well and we’re happy to share!
November 18, 2025 at 4:15 PM
We couldn’t have taken this study to the next level without Omaya and Marine from team @dudinlab.bsky.social and Amy and Lauren from team @amyweeks.bsky.social . Together their talents brought the additional molecular and structural clarity we needed to model this circuit’s behavior fully.
November 18, 2025 at 4:15 PM
This work shines because of @zjmaggiexu.bsky.social passion for these cells. She built it all—the cultures, transcriptomes, analyses, modeling and collaborations—from scratch. I can’t begin to express how brilliant and hard-working a scientist she is (and she's 👀 for postdocs!). So proud of her 🥲
November 18, 2025 at 4:15 PM
More broadly, this circuit’s architecture provides a general control logic for organizing number and size of natural and engineered sub-cellular structures. Morphological circuits like this one can be viewed as building blocks for cell structure, analogous to network motifs and circuit topologies.
November 18, 2025 at 4:15 PM
While our model was built to describe P. collini’s trap scaling, we found that the trap geometries of other suctorian species from different niches could be modeled as re-parameterizations or extensions of this same core control logic!
November 18, 2025 at 4:15 PM