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Reposted by Chalystha Lee

NYU Pain Research Center @nyupainresearch.bsky.social · Sep 10

The Margolis Lab had a great time at #ANMS2025 in Minneapolis! Postdocs Sarah, Lin & Chalystha gave abstract talks, PRC Director Kara closed the conference, and we met Keynote Speaker & 2021 Nobel Laureate David Julius and his team! #ANMS225

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Reposted by Chalystha Lee

NYU Pain Research Center @nyupainresearch.bsky.social · Sep 10

PRC Highlight: #MargolisLab making strides again! Congrats to Chalystha Lee who received the 2025 ISSR Travel Award at the #ISSR2025 hosted in Vienna! With mentorship from Dr. Kara Margolis & Dr. Michael Gershon lighting the way. #mentorship #ISSR #womeninresearch @chalysthalee.bsky.social

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Reposted by Chalystha Lee

Nesia Zurek, PhD @docnessmonster.bsky.social · Aug 7

Gabapentin is widely prescribed for nerve pain, but it doesn’t work the same for everyone.

We studied actual human sensory neurons from donors and found that some responded strongly - and others hardly at all.
#fromlabtolife #neuroskyence #PainResearch 1/4

Alt text (expanded version for web or accessibility-focused platforms):
Vertical infographic titled “Why Gabapentin Works Differently for Different People.”
Section 1 explains that 10% of adults live with neuropathic pain and gabapentin doesn't help everyone.
Section 2 shows that researchers used donated human dorsal root ganglia (DRG) neurons to study gabapentin’s effects, combining electrophysiology and RNA sequencing.
Section 3 illustrates how gabapentin reduced excitability in some donors’ neurons but not others, and those differences matched gene expression profiles.
Section 4 highlights how this could lead to more personalized pain treatment that adds life to the years of people living with chronic pain.
Footer credits the donors and includes the study DOI

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Chalystha Lee @chalysthalee.bsky.social · Jul 15

@margolislabnyu.bsky.social @nyupainresearch.bsky.social

Chalystha Lee @chalysthalee.bsky.social · Jul 15

Just back from a great week in Vienna for #ISSR2025. I am grateful for the travel award and the opportunity to share my work. Big thanks to @karapedsgastrodoc.bsky.social and Mike Gershon for their steady support in the lab and my career. Loved connecting with 5-HT researchers from around the world!

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Chalystha Lee @chalysthalee.bsky.social · Jul 8

#ISSR2025

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Chalystha Lee @chalysthalee.bsky.social · Jul 8

@karapedsgastrodoc.bsky.social gave a fantastic talk on the lab's important work on SSRI use in the gastrointestinal tract
@margolislabnyu.bsky.social highlighting @linyhung.bsky.social and @sarahanajjar.bsky.social 's work!
@nyupainresearch.bsky.social

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Chalystha Lee @chalysthalee.bsky.social · Jul 8

Excited to learn about all things Serotonin / 5HT at #ISSR2025 in Vienna!

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Reposted by Chalystha Lee

Pain Research Forum @painresforum.bsky.social · Jun 30

What do you think these #painresearch results from Ullrich et al. in Science Advances may mean for finding the patterns behind ligand bias? bit.ly/4elhYYE

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Reposted by Chalystha Lee

NYU Pain Research Center @nyupainresearch.bsky.social · May 31

And just like that, AMPIRS takes its final bow! 🎬Huge cheers to our grand finale presenters and a confetti cannon 🎉 of congrats to all the Flash Talk, Poster and Oral Presentation champs! 🏆 You dazzled, you delivered, you definitely deserve it! #PRCpride #MPBpride

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Chalystha Lee @chalysthalee.bsky.social · Jun 11

Congratulations @tonelloraquel.bsky.social and @mariafialho.bsky.social !! Fantastic work!

Raquel Tonello @tonelloraquel.bsky.social · Jun 11

Excited to share my first senior author paper in Pain! 🎉 We identify Synaptojanin 1 & Endophilin A1 as key endocytic mediators of nociception. Silencing them blocks spinal synaptic transmission and relieves pain in cancer & postoperative models, without affecting normal behavior.
buff.ly/caKMGY3

buff.ly

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Chalystha Lee @chalysthalee.bsky.social · Jun 3

Congratulations @sarahanajjar.bsky.social & @linyhung.bsky.social !! 🙌🥳

MargolisLab @margolislabnyu.bsky.social · Jun 2

🎉 Big wins for the Margolis Lab at AMPIRS 2025!

👏 Chalystha and Lin rocked their talks, Taeseon and Daniel nailed their posters, and Sarah delivered an epic flash talk!

🏆 Huge congrats to Lin and Sarah for taking 1st place! So proud of this amazing team! 💜🧠
@karapedsgastrodoc.bsky.social

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Reposted by Chalystha Lee

Ted Price @tedpricethepainguy.bsky.social · May 14

BOOM! www.nature.com/articles/s41... I think this is a big step forward for the field. Congrats to Lauren Donovan and @vivtawfik-mdphd.bsky.social and the whole Tawfik lab team.

Aging and injury drive neuronal senescence in the dorsal root ganglia - Nature Neuroscience

The authors describe a susceptibility of the peripheral nervous system to neuronal senescence with age or injury relevant for sensory dysfunction, such as chronic pain.

www.nature.com

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Reposted by Chalystha Lee

Emilia Favuzzi @emiliafavuzzi.bsky.social · May 22

I am looking for a postdoc with an immunology background interested in joining a Yale neuroscience lab to study how the brain controls immunity. At Yale, we have a wonderful interdisciplinary & collaborative #neuroimmune community. Please reach out or share with anyone who might be interested!

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Reposted by Chalystha Lee

Kuchroo Lab @kuchroolab.bsky.social · May 23

🚨New paper with @thexavierlab.bsky.social @science.org on the critical role of 🔄neuroimmune crosstalk in immune defense in the gut🪱🪱.
🧪@genelayinstitute.bsky.social @mgbresearch.bsky.social @harvardmed.bsky.social @broadinstitute.org
www.science.org/doi/10.1126/...

Type 2 cytokines act on enteric sensory neurons to regulate neuropeptide-driven host defense

Enteric nervous system (ENS)–derived neuropeptides modulate immune cell function, yet our understanding of how inflammatory cues directly influence enteric neuron responses during infection is conside...

www.science.org

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Reposted by Chalystha Lee

NYU Pain Research Center @nyupainresearch.bsky.social · May 21

Congrats to @karapedsgastrodoc.bsky.social on becoming part of the 2025 AGA Council section leaders!! Read more👉 gastro.org/news/meet-ou...

Meet our 2025 AGA Council section leaders

Introducing the five members elected to join the AGA Institute Council and lead specialty-based sections.

gastro.org

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Chalystha Lee @chalysthalee.bsky.social · Apr 12

Definitely something important to consider wrt our studies in rodent preclinical models!

NYU Pain Research Center @nyupainresearch.bsky.social · Apr 10

New study finds microglia-like cells in human DRGs that drive neuronal soma enlargement, axon growth, and somatosensation but are absent in mice 🪤🐁🐀 www.cell.com/cell/fulltex...

Peripheral nervous system microglia-like cells regulate neuronal soma size throughout evolution

An immune cell population found in humans and a number of large vertebrates resembles microglia of the central nervous system in terms of transcriptome, epigenome, protein markers, and ontogeny but in...

www.cell.com

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Reposted by Chalystha Lee

tBerta Lab @tbertalab.bsky.social · Apr 8

🔬 Exciting discovery! We've been curious about the function of unique IBA1+ cell staining we observed around healthy human DRG neurons in the lab (indicated by red arrows). A new paper @cellpress.bsky.social finally provides some answers. Link: www.cell.com/cell/fulltex...

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Chalystha Lee @chalysthalee.bsky.social · Apr 9

Well done, Woo-Tae! 🙌

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Reposted by Chalystha Lee

Lauren Atlas @laurenatlas.bsky.social · Apr 7

We have slots for 2-3 postbacs! Get in touch if you’re interested in joining the Affective Neuroscience and Pain lab & contributing to our studies of pain, emotion, and social processing in the 🧠

Dan Handwerker @danielhandwerker.bsky.social · Apr 7

Recruitment of postbacs & postdocs in the NIH IRP has resumed. I have no additional info beyond what is publicly stated on the website. www.training.nih.gov/research-tra...

Text copied from website on April 7, 2025 stating "Recruitment of new postbacs has resumed. Please read program information below and use the 'Start your application' link to apply."

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Reposted by Chalystha Lee

Gemma C. Atkinson @gemmaatkinson.bsky.social · Apr 8

last day to apply for a post-doc position in my group #phagesky #microsky

Gemma C. Atkinson @gemmaatkinson.bsky.social · Mar 19

Please spread the word! We have an opening in the Atkinson lab for a post-doc with a focus on the molecular mechanisms of microbial immune systems. Can be a fully computational or experimental or hybrid project.

Read more and apply here:
lu.varbi.com/en/what:job/...
#phage #bioinformatics

Postdoctoral research fellow with a focus on the molecular mechanisms of bacteriophage-host interactions

Description of the Workplace In the Atkinson lab we are interested in making discoveries about protein function and structure, with a focus on bacterial immune system components that protect against b

lu.varbi.com

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Reposted by Chalystha Lee

Patrik Ernfors @patrikernfors.bsky.social · Mar 24

How is the input of the different kinds of primary sensory neurons responding to heat and mechanical stimuli summarized in the spinal cord? Check out our recent study.

www.nature.com/articles/s41...

Neural ensembles that encode nocifensive mechanical and heat pain in mouse spinal cord - Nature Neuroscience

Zhang et al. identify unimodal neural representations in the spinal cord of cutaneous mechanical and heat stimuli gated by a shared feed-forward local inhibitory neuron type and a neural transition du...

www.nature.com

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Reposted by Chalystha Lee

NYU Pain Research Center @nyupainresearch.bsky.social · Mar 20

CONGRATULATIONS to Drs. Sarah Najjar, Lin Hung and Kara Margolis- Their review article: Serotonergic Control of Gastrointestinal Development, Motility, and Inflammation is one of the top 10 most cited articles published in 2023! onlinelibrary.wiley.com/doi/abs/10.100… 🥳🔝🔟

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Reposted by Chalystha Lee

Ted Price @tedpricethepainguy.bsky.social · Mar 19

Our program manager extraordinaire, Ayesha Ahmad, is leaving us, so we have an exciting position open to take on her role. jobs.utdallas.edu/postings/28956 In addition to this being an exciting position, you will also get to learn from Ayesha before she departs.

Program Manager I

This position will be responsible for managing and overseeing the day-to-day operations of the Human Nociceptor and Spinal Cord Molecular Signature Center under the direction of Dr. Ted Price. Key dut...

jobs.utdallas.edu

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Reposted by Chalystha Lee

Joana F Neves @nevesjf.bsky.social · Mar 3

Looking for an excellent & highly motivated postdoctoral researcher to join our team to develop an exciting project focused on the generation of beneficial Innate Lymphoid Cells #ILC for the treatment of Inflammatory Bowel Disease #IBD using #organoids. Please share!
www.kcl.ac.uk/jobs/109186-...

www.kcl.ac.uk

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