Lightnews — Scholar-powered news

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · 12d

It’s a spectrum and it has certainly moved

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · 12d

To say the least!

1

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · 12d

I believe it’s important that all Americans remain abreast of official White House communications.

The Voice of our democratic republic is being used for petty cult.

Meantime health research administrative staff has been cut so heavily that not a single contract can be executed.

2 2

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · 13d

God bless America

3

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · 14d

“There is an evil which I have seen under the sun, as an error which proceedeth from the ruler: Folly is set in great dignity, and the rich sit in a low place.

“The words of wise men are heard in quiet more than the cry of him that ruleth among fools.”

—Ecclesiastes 10:5–6, 9:17

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · 17d

Great to see Taiwan’s 唐鳳 Audrey Tang @audreyt.org justly celebrated in Nexus, the latest book from Yuval Noah Harari.

3 15

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · 20d

Lovely window visitor in Taipei 🥰 🐦‍⬛

3

Reposted by Chase W. Nelson 倪誠志

Senator Bernie Sanders @sanders.senate.gov · 21d

Yes, the war in Gaza is a genocide.

I hope you’ll take a moment to read my op-ed here:

It Is Genocide » Senator Bernie Sanders

Hamas, a terrorist organization, began this war with its brutal attack on October 7, 2023, which killed 1,200 innocent people and took 250 hostages. Israel, as any other country, had a right to defend...

www.sanders.senate.gov

190 640 2.8K

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · 22d

A full day with the Constitution. Have you read it? What did you find most surprising about it?

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · 22d

Officially a genocide.

New York Times Opinion @nytopinion.nytimes.com · 22d

“Israel has committed genocide against Palestinians in Gaza. This finding is based on investigations and extensive evidence,” writes Navi Pillay, the head of a U.N. commission. “It has been corroborated by multiple sources.”

Opinion | My U.N. Commission’s Finding: Israel Is Committing Genocide

The chief judge of the Rwandan genocide tribunal has concluded that Israel is guilty of the “crime of crimes” in Gaza.

nyti.ms

1

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · 24d

Thank you so much for the thoughts, Justin! I'm definitely on the same page about technical science work—specificity and formality is great. But I look at a bunch of science and other lay audience books and it seems like almost no one uses the middle initial, making me second guess things!

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · 24d

Dear friends, I’d love your input: I’m planning to submit some writing to a general-audience magazine and I’m torn about how to sign my name. Which feels better to you and why?

(1) Chase W. Nelson
(2) Chase Nelson

Thanks so much!

1 1

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · 26d

This looks incredible!

1

Reposted by Chase W. Nelson 倪誠志

Ed Hollox @edhollox.bsky.social · Sep 4

Academics! Delighted to announce that the new 3rd edition of Human Evolutionary Genetics is now available to book inspection copies. Available to buy January 9th. 1/5
www.routledge.com/Human-Evolut...

Human Evolutionary Genetics

Human Evolutionary Genetics reaches its third edition at a time when sequencing and analyzing whole genomes, modern and ancient, has become rapid, affordable, and routine. These advances have led to a...

www.routledge.com

3 3 8

Reposted by Chase W. Nelson 倪誠志

Evan Irving-Pease @evanirvingpease.bsky.social · May 8

Delighted to see our paper on the evolutionary history of the CCR5Δ32 deletion published this week in @cellpress.bsky.social. Work led by @ravnkirstine.bsky.social, Leonardo Cobuccio and Rasa Muktupavela, and co-supervised by me and @simorasmu.bsky.social. See 🧵 for main findings...

Graphical abstract: The chemokine receptor variant CCR5delta32 is linked to HIV-1 resistance and other conditions. Its evolutionary history and allele frequency (10%–16%) in European populations have been extensively debated. We provide a detailed perspective of the evolutionary history of the deletion through time and space. We discovered that the CCR5delta32 allele arose on a pre-existing haplotype consisting of 84 variants. Using this information, we developed a haplotype-aware probabilistic model to screen 934 low-coverage ancient genomes and traced the origin of the CCR5delta32 deletion to at least 6,700 years before the present (BP) in the Western Eurasian Steppe region. Furthermore, we present strong evidence for positive selection acting upon the CCR5delta32 haplotype between 8,000 and 2,000 years BP in Western Eurasia and show that the presence of the haplotype in Latin America can be explained by post-Columbian genetic exchanges. Finally, we point to complex CCR5delta32 genotype-haplotype-phenotype relationships, which demand consideration when targeting the CCR5 receptor for therapeutic strategies.

2 13 26

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · 27d

Headed to Bangkok, Thailand 🇹🇭 Oct 23–26 for a science conference. First time. If I add 1–2 days, what should I not miss? 🙏

3

Reposted by Chase W. Nelson 倪誠志

bioRxivpreprint @biorxivpreprint.bsky.social · Sep 2

SimHumanity: Using SLiM 5.0 to run whole-genome simulations of human evolution https://www.biorxiv.org/content/10.1101/2025.09.01.673541v1

2 3

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · 27d

It is not the bigness of our concern for certain lives, but the smallness of our concern for countless others, that stands correction.

1

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · Sep 8

Darwin described characteristics that revert or evolve to the same state—what we refer to as homoplasies—as “mocking” each other. I appreciate this description. I often feel they are mocking me.

1

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · Sep 6

A crystalline day in Taipei, Tiger Mountain 虎山 in claw’s reach.

5

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · Sep 6

The strategic end is born in the tactics with which it is pursued.

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · Sep 6

The United States is arming a terrorist regime that has the audacity to call itself Israel.

In the words of Lieutenant Colonel Anthony Aguilar, a 25-year U.S. Army Green Beret: “the people back home need to know they’re funding a genocide.” www.nytimes.com/2025/09/05/w...

Israel Steps Up Attacks on Gaza City Ahead of a Planned Wider Offensive

www.nytimes.com

1

Reposted by Chase W. Nelson 倪誠志

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · Sep 3

Announcing SimHumanity, a baseline SLiM 5.0 model of the full human genome, replete with demographic history, autosomes, X/Y, and mtDNA. A shared starting point for reproducible evolutionary simulations. We’d love your feedback! #SLiM #evolution #genomics www.biorxiv.org/content/10.1...

SimHumanity: Using SLiM 5.0 to run whole-genome simulations of human evolution

The reconstruction of human evolutionary history has undergone repeated advances, each made possible by methodological innovations. In recent decades, genetic and genomic data played a central role in...

www.biorxiv.org

22 30

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · Sep 3

Announcing SimHumanity, a baseline SLiM 5.0 model of the full human genome, replete with demographic history, autosomes, X/Y, and mtDNA. A shared starting point for reproducible evolutionary simulations. We’d love your feedback! #SLiM #evolution #genomics

bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · Sep 2

SimHumanity: Using SLiM 5.0 to run whole-genome simulations of human evolution https://www.biorxiv.org/content/10.1101/2025.09.01.673541v1

1 1

Chase W. Nelson 倪誠志 @chasewnelson.bsky.social · Sep 3

Announcing SimHumanity, a baseline SLiM 5.0 model of the full human genome, replete with demographic history, autosomes, X/Y, and mtDNA. A shared starting point for reproducible evolutionary simulations. We’d love your feedback! #SLiM #evolution #genomics www.biorxiv.org/content/10.1...

SimHumanity: Using SLiM 5.0 to run whole-genome simulations of human evolution

The reconstruction of human evolutionary history has undergone repeated advances, each made possible by methodological innovations. In recent decades, genetic and genomic data played a central role in...

www.biorxiv.org

22 30