Curious about how the metabolic decoy strategy can reduce fungal pathogenic colonization and protect plants? Visit poster P-236 this afternoon at #2025ISMPMI

@binebrumm.bsky.social, together with @dromius.bsky.social team colleagues, unveiled how key proteins act as 'sculptors' in plant cells, taking on different roles to shape development

Read more www.slcu.cam.ac.uk/news/plant-c...
And full paper doi.org/10.1126/scia...

Excited to share that our preprint has found a home in Science Advances. We show that intrinsically disordered regions determine the functional diversification of actin-regulatory SCAR proteins in Medicago. 🧵 1/3
www.science.org/doi/full/10....
#ScienceAdvances #PlantScience #IDRs

📜 MetaFlowTrain: a highly parallelized and modular fluidic system for studying exometabolite-mediated inter-organismal interactions

🧑‍🔬 @chesneau-g.bsky.social, @hacquardst.bsky.social, et al.

📔 @naturecomms.bsky.social

🔗 www.nature.com/articles/s41...

#️⃣ #PlantScience #PlantImmunity #PlantMethods

5/5. MetaFlowTrain confirms that specific bacterial exometabolites, not media depletion, drive microbial antagonism.
🦠 Pseudomonas R401 WT suppresses SynCom growth via known inhibitory exometabolites.
❌ A triple mutant loses inhibitory power.

4/5. MetaFlowTrain dissects inter-kingdom microbial interactions via directional exometabolite flow.
🦠 Bacterial SynComs strongly inhibit fungal growth, even without physical contact.
🚫 Up to 82% growth suppression via exometabolites.

3/5. MetaFlowTrain reveals how soil conditioning alters microbial assembly/exometabolite output.
🦠 SynComs exposed to plant-conditioned peat undergo major community shifts & consume key metabolites (α-KG, fumarate).
🌱 BF SynCom-derived exometabolites impact Arabidopsis germination & root growth.

2/5. MetaFlowTrain cultivates diverse microbes & collects their exometabolites under continuous nutrient flow.
🌱 Using sterile peat extract, we grew 11 bacterial & 4 fungal strains from the Arabidopsis root microbiota.
💥 Exometabolite profiles differed significantly by strain.

📝 Paper: www.nature.com/articles/s41...
1/5. 🚂 MetaFlowTrain = 4 modular components:
a. Variety of liquid inputs
b. 24-channel pump enabling parallel metabolic trains
c. 3D-printed gnotobiotic microchambers
d. Multi-layered outputs for cell/metabolite analysis
🔗 protocols.io/view/36wgqd68ovk5/v3

🚨Excited to share our new publication! MetaFlowTrain, a highly parallelized and modular fluidic system to study exometabolite interactions between microbes-microbes-plants 🌱
@hacquardst.bsky.social @herpell.bsky.social S.Wolf S.Perin @mpipz.bsky.social
www.youtube.com/watch?v=gNUf...
🧵Thread 5/5:

Our manuscript describing MYCroplanters, a high-throughput Arabidopsis phenotyping tool is out today in Plos Pathogens from first authors Melissa Chen and Leah Fulton! journals.plos.org/plospathogen...

Grateful to the #RPB2025 community for the inspiring scientific exchanges and to IRHS-Angers for organizing such a fantastic 17th Plant-Bacteria Interaction Meeting 🌱🦠. Honored to have been invited to present my work in this incredible setting! ⛰️❄️

First paper of our lab today @natureportfolio.bsky.social by Nussi!

We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!

@embl.org #RNAbiology #RNASky

t.co/a24Xxcxdo0

It’s out!! We subjected soils from 30 different locations across Europe to extreme events and found that soil fungal and bacterial communities showed consistent responses that could be predicted from their origin! With @knightjar.bsky.social and many collaborators!
www.nature.com/articles/s41...