Chiara Stringari
@chiarastringari.bsky.social
660 followers 1.8K following 11 posts
Scientist at @cnrs.bsky.social @laboptbio.bsky.social https://lob.ip-paris.fr/chiara-stringari Label-free optical microscopy and metabolic imaging. 'Science doesn't care about what you believe'
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Reposted by Chiara Stringari
ebeaurepaire.bsky.social
Happy to finally publish this work… Congrats authors and thanks funders @agencerecherche.bsky.social #FondationBettencourtSchueller‬‬‬
Reposted by Chiara Stringari
ebeaurepaire.bsky.social
These findings help to establish THG microscopy as a quantitative, multiscale imaging technique, paving the way for new applications. 📖 #Neuroscience #Myelin #THG #Microscopy #Research
Reposted by Chiara Stringari
ebeaurepaire.bsky.social
Fun fact for multiphoton microscopy geeks: aberrations caused by vertical micro-interfaces appear to be a significant contrast mechanism in polarized THG imaging. 😎
Reposted by Chiara Stringari
ebeaurepaire.bsky.social
Finally, we illustrate the relevance of pTHG microscopy for characterizing myelin distribution at different scales in fixed mouse and human brain tissue.
Reposted by Chiara Stringari
ebeaurepaire.bsky.social
Our study presents a systematic characterization of polarized THG (pTHG) signals from individual axons, enabling the derivation of myelin scores in various systems. 🐭🐟
We confirm the sensitivity of THG for myelin in mouse tissue and detect early axon development in zebrafish.
Reposted by Chiara Stringari
ebeaurepaire.bsky.social
We show that axons exhibit complex pTHG profiles that depend on axon morphology and can't be explained by classical models. We establish a numerical strategy to relate pTHG profiles to axon diameter and myelin thickness, taking into account myelin-induced optical aberrations.
Reposted by Chiara Stringari
ebeaurepaire.bsky.social
Multiscale characterization of myelin distribution with polarized THG microscopy
Morizet et al, Optica 2025 doi.org/10.1364/OPTI...

@laboptbio.bsky.social @institutducerveau.bsky.social @cnrs.fr ‪‪ @ip-paris.bsky.social @inserm.fr
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Reposted by Chiara Stringari
ebeaurepaire.bsky.social
By #J_Morizet #N_Olivier #MS_Aigrot #P_Mahou #E_Martin #A_Desmazieres #B_Stankoff @chiarastringari.bsky.social

🔬🌟 Find out how Third Harmonic Generation (THG) microscopy could help advance myelin biomedical research! 🧠
Reposted by Chiara Stringari
laboptbio.bsky.social
Congratulations to Amelie Elouin on her brilliant defence of her PhD thesis, entitled 'Investigating the role of Myosin II in collective cell migration during gastrulation in the zebrafish Danio rerio' !
chiarastringari.bsky.social
Congratulations @caporalclement.bsky.social
And it was an honor to have you at LOB!
laboptbio.bsky.social
Congratulations to @caporalclement.bsky.social on his brilliant defence of his PhD thesis, entitled 'Quantitative Analysis of Large Volume Imaging in Developmental Neurobiology' !
Reposted by Chiara Stringari
faldalf.bsky.social
Excited to be in Genoa for the #WeberSymposium2025

A few days of all fun things fluorescence ahead 🔬🎆🌈

Starting out with an account of the seminal contributions by Gregorio Weber presented by the amazing Dave Jameson
chiarastringari.bsky.social
The talk "Fluorescence Lifetime Microscopy (FLIM) for label-free metabolic imaging of living tissues" given at the #VirtualPub of @eurobioimaging.bsky.social is now online!
#FLIM
www.youtube.com/watch?v=WC1V...
Reposted by Chiara Stringari
chris-schaffer.bsky.social
Scientist colleagues, write to your hometown paper and tell folks about your work, what motivates it, and what impact it could have. Aim for publication June 16.
cornellasap.bsky.social
Federal research cuts impact local economies, and stall progress.

Publish an opinion piece in your hometown paper on June 16th to SPREAD THE WORD about how scientific research contributes to the everyday health and wealth of the general public.

#McClintockLetters

blogs.cornell.edu/asap/events-...
Reposted by Chiara Stringari
laboptbio.bsky.social
Congratulations to Stella Dees for defending her thesis on "Multicontrast 3P-microscopy for biological tissue imaging"
Reposted by Chiara Stringari
laboptbio.bsky.social
Congratulation to Giulia Galante for her thesis defense about the "Characterization and physico-chemical monitoring of collagen degradation in parchments by polarization-resolved multiphoton microscopy!
Reposted by Chiara Stringari
imn-bordeaux.bsky.social
📰 New article published in @nature.com entitled "A human brain map of mitochondrial respiratory capacity and diversity" 🧠

An international research team has created a map revealing the diversity of #mitochondrial phenotypes in the human #brain

✒️ By @micheltds.bsky.social and all

📌 For more ⬇️
A human brain map of mitochondrial respiratory capacity and diversity - Nature
The ability to physically partition the human brain at a spatial resolution comparable to neuroimaging methods enabled the development of a brain-wide atlas of mitochondrial content, specialization an...
www.nature.com
Reposted by Chiara Stringari
Reposted by Chiara Stringari
paulamonterollopis.bsky.social
Truly proud of everyone at QUAREP LiMi WG11. We defined “bare-minimal” guidelines for microscopy reporting to improve reproducibility in light microscopy. Check out our Zenodo upload! zenodo.org/records/1497.... Thank you all who contributed! Our comprehensive guidelines will come next!
QUAREP - Bare Minimal Microscopy Reporting Requirements Checklist
Checklist of the bare minimum requirements for reporting microscopy experiments. Table 1 presents the checklist based on the REMBI metadata model (Figure 1), including examples to facilitate interpret...
zenodo.org
Reposted by Chiara Stringari
melaniebergma18.bsky.social
1/n New study estimates that #microplastics could reduce the photosynthesis of terrestrial plants by about 12% and by about 7% in marine algae, which are at the base of the ocean food web and capture #CO2 buffering #ClimateChange.
#plastic
www.theguardian.com/environment/...
Microplastics hinder plant photosynthesis, study finds, threatening millions with starvation
Researchers say problem could increase number of people at risk of starvation by 400m in next two decades
www.theguardian.com
Reposted by Chiara Stringari
jytinevez.bsky.social
Do you love and use #microscopy?
There is a fantastic event taking place at the @institutpasteur.bsky.social Paris in 3 weeks, just for you :)

1/ mini symposium on imaging,
AND / OR
2/ book demo slots to test the latest microscopes from partners

Please share with colleagues, more below👇
Reposted by Chiara Stringari
grafffio.bsky.social
Et je ne résiste pas à partager celle-ci de la flamboyante @chiarastringari.bsky.social aujourd'hui à Paris !

Science is not opinion
#Standupforscience
@standupforscifr.bsky.social
Chiara tenant une pancarte "Science is not opinion" devant la faculté de Jussieu.