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Reposted by Christine Moissl-Eichinger

The Daum Lab @daumlab.bsky.social · 2d

Out in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...

Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail

This structure of an archaeal tailed virus (arTV) provides detailed insights into arTV assembly and infection mechanisms.

www.science.org

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Reposted by Christine Moissl-Eichinger

Sonja-Verena Albers @archaellum.bsky.social · 21d

Happy to share that our story on the bacterial archaellum was published today in @natmicrobiol.nature.com
www.nature.com/articles/s41...

Congrats to the authors: @sshamphavi.bsky.social @loumollat.bsky.social @mariejoest.bsky.social Najwa Taib and @sgribaldo.bsky.social

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Christine Moissl-Eichinger @chmoei.bsky.social · 28d

This study was led by my amazing PhD student @theeonflux.bsky.social and @chriku.bsky.social with great collaborators + support from @fwf-at.bsky.social and RESPImmun @medunigraz.at

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Christine Moissl-Eichinger @chmoei.bsky.social · 28d

🚨 New preprint!
We built the largest respiratory pan-microbiome atlas yet >4,000 metagenomes from nose to lung.
👉 In health: a connected microbial continuum
👉 In disease: this structure collapses

#microbiome #microsky

Read: www.biorxiv.org/content/10.1...

Pan-microbiome analysis along the human respiratory axis reveals an ecological continuum in health and collapse in disease

The human respiratory tract (RT) harbors complex microbial communities whose functions are critical to health and disease. Yet, current insights remain fragmented across anatomical sites, populations,...

www.biorxiv.org

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Reposted by Christine Moissl-Eichinger

Sonja-Verena Albers @archaellum.bsky.social · Aug 20

🚨 Imagine a bacterium that refuses to follow the textbook:
It grows as tangled filaments, divides unevenly, reshapes its own membranes… and even builds grappling hooks.
Meet Litorilinea aerophila — and here’s why it blew our minds.

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Reposted by Christine Moissl-Eichinger

Medizinische Universität Graz @medunigraz.at · Aug 8

Neues aus der Mikrobiom-Forschung!
Archaeen – kaum bekannte Mitbewohner in unserem Darm – senden winzige Bläschen, um mit ihrer Umwelt zu kommunizieren.
Ein Team der Med Uni Graz hat das jetzt erstmals detailliert beschrieben. Veröffentlicht in Nature Communications ➡️ https://bit.ly/47gnl9R.

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Christine Moissl-Eichinger @chmoei.bsky.social · Aug 5

Here you will find all details on the project and how to apply. Please apply only through this webpage (emails cannot be considered): www.medunigraz.at/en/doctoral-... (our project is listed on page 22 in "Projects")

PhD Application and Admission

www.medunigraz.at

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Christine Moissl-Eichinger @chmoei.bsky.social · Aug 5

🚨 2 funded #PhD positions (ERC Adv Grant) in the Moissl-Eichinger Lab, Graz! Study Methanobrevibacter as a keystone in the gut microbiome.
💡 Omics, modeling, synthetic consortia
📅 Deadline: Sept 10, 2025
🌍 Int’l applicants welcome!
Application link below.
#microbiomesky #archaeasky #microsky

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Christine Moissl-Eichinger @chmoei.bsky.social · Jul 7

Wow, congrats Simo!!! Well deserved!!!

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Christine Moissl-Eichinger @chmoei.bsky.social · Jun 27

Congratulations to all winners - and "happy World Microbiome Day"!!

Cluster of Excellence 'MicroPlanet' @microbesplanet.bsky.social · Jun 27

Today, June 27, marks World Microbiome Day! We're celebrating with the inaugural Austrian Microbiome Research Awards. Congrats to Cornelia Rottensteiner @cornelia-cr.bsky.social @cemess.bsky.social @univie.ac.at, Charlotte Neumann @medunigraz.at, and Daniela Wöber @AIT. @fwf-at.bsky.social Details👇

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Christine Moissl-Eichinger @chmoei.bsky.social · Jun 18

So grateful. Let’s dive deeper into the archaeome!!

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Christine Moissl-Eichinger @chmoei.bsky.social · Jun 18

This is not a solo achievement. It’s the result of years of support, teamwork (cudos to the amazing MEL TEAM), and inspiring collaborations. Huge thanks to my incredible team, the @medunigraz.at environment, and all our partners.

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Christine Moissl-Eichinger @chmoei.bsky.social · Jun 18

Some big news: I’ve been awarded an ERC Advanced Grant to further explore the roles of #archaea in gut #microbiomes and beyond.
@erc.europa.eu
#ERCAdG #ARCHMETH #Microbiome #Archaea #sciencepassion

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Reposted by Christine Moissl-Eichinger

Medizinische Universität Graz @medunigraz.at · Jun 17

Klimaschutz trifft Darmgesundheit: Unsere Mikrobiomexpertin Christine Moissl-Eichinger erhält den prestigeträchtigen Advanced Grant (2,5 Mio. €) des für ihre Forschung zu Methanobrevibacter – einem winzigen Mikroorganismus mit großem Potenzial ➡ https://bit.ly/3FDDJpO.

#ERCAdG

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Reposted by Christine Moissl-Eichinger

Cluster of Excellence 'MicroPlanet' @microbesplanet.bsky.social · Jun 13

New @fwf-at.bsky.social CoE Microplanet Publication in NatureComms! @theviktoriaeffect.bsky.social from the lab of @chmoei.bsky.social @medunigraz.at profiled the proteome & metabolome of extracellular vesicles from key gut archaea, revealed immune-stimulating capacities and unique molecular cargo.

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Christine Moissl-Eichinger @chmoei.bsky.social · Jun 13

Proud to share this collaborative effort—thank you to the entire team @, to @medunigraz.at, all our collaborators and their teams + @microbesplanet.bsky.social, and of course @fwf-at.bsky.social for financial support!

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Christine Moissl-Eichinger @chmoei.bsky.social · Jun 13

This work sheds light on the trophic control Archaea may exert over the cancer microbiome, urging us to rethink their role in health and disease.

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Christine Moissl-Eichinger @chmoei.bsky.social · Jun 13

🔍 Using metabolic modeling, co-culture assays, and metabolomics, we show that:
• M. smithii forms mutualistic interactions with CRC-associated bacteria like Fusobacterium nucleatum
• It enhances bacterial growth and metabolite production
• It produces tumor-modulating archaeal metabolites

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Christine Moissl-Eichinger @chmoei.bsky.social · Jun 13

In this study, amazing @roxymzh.bsky.social screened over 1,800 metagenomes from 19 clinical cohorts and found that Methanobrevibacter smithii—the dominant gut archaeon—is consistently enriched in colorectal cancer (CRC) patients.

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Christine Moissl-Eichinger @chmoei.bsky.social · Jun 13

🚨 New preprint alert!
We report what might be the first mechanistic link between gut Archaea and human disease.
Methanobrevibacter smithii is enriched in CRC patients—and boosts growth of cancer-associated bacteria like F. nucleatum.
www.biorxiv.org/content/10.1...
@archaeasky @microbiomesky

Methanobrevibacter smithii associates with colorectal cancer through trophic control of the cancer bacteriome

The human gut is colonized by trillions of microbes that influence the health of their human host. Whereas many bacterial species have now been linked to a variety of different diseases, the involveme...

www.biorxiv.org