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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 13h

I think I may follow the lead of others who have reverted to mid-2010s social media activity when many/most of us would blog elsewhere and then use social media such as Twitter as distribution channels. For those who don't want to bother with their own blogs , #linkedin is decent

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 14h

Can anyone articulate the value of the value based care in chronic kidney disease in the era of the #4pillars? Trad #vbc was based on the premise that generic angiotensin blockade was sufficient (false) and underutilized (proven to be wrong by the #upmc trial that demonstrated that the perceived […]

Original post on mastodon.social

mastodon.social

Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 1d

The screenshots are so cool (discussed mortality up to the end of 2023)

Interview in late 2025 discusses excess deaths (estimated as 2% by the interviewee and attributed to long covid) and drops in mortality due to glp1ra estimated to be ~6% by 2030 […]

[Original post on mastodon.social]

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 1d

One cannot avoid brute memorization in med school. For starters, many medical situations require very fast response ie one does not have the luxury of time to think things through. Secondly, the sheer volume of material that one has to master to finish med […]

[Original post on mastodon.social]

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 1d

Premature closure is close tie to analysis- paralysis and therapeutic inertia as cause for bad medical decision making. In an attempt to address the last two , AI deployment in the medical space will exacerbate the former as no one will take a few moments to fact check the AI.

Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 2d

@auscandoc the trial has not been presented yet , but here is Lilly's announcement.

https://investor.lilly.com/news-releases/news-release-details/lillys-mounjaro-tirzepatide-gipglp-1-dual-agonist-demonstrated

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 2d

I expect the #glp1ra online and in-real-life shaming and bullying to get worse after the publication of #SURPASS-CVOT #Tirzepatide #dulaglutide.
I think my #gigablock game will surpass (pun intended) my peak of the early pandemic era esp after I have gone through the egfr data.

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 4d

Are there any #gpus offering high counts of integer operations per second? I have tested a bunch of NVIDIAs, and their integer arithmetic throughput is definitely smaller than their FP32.

Reposted by Christos Argyropoulos MD PhD

@GottaLaff @gottalaff.bsky.social · 8d

CNBC: Consumer confidence is lower than expected as Wall Street braces for shutdown data blackout

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 9d

Colleagues, patients, former students, and random followers in social media have been sending me this *great news* in DMs, emails, and text.

Great day today for #zerokale.

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 10d

All will be well prehistoric kitties

Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 10d

Many of the weird things that you hear people say or do are, at core, a rejection of reality because the problems of the latter are hard to contemplate and solve by those who were raised in the culture of the make believe. The crash landing will be very hard.

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 10d

The proper summary of the RECOVER anosmia study is that a large %(×) of the population don't know they have smell impairment and that a history of covid increases the risk by *10%*.

(×) The percentage will depend on cohort selection and technique to ascertain the loss of smell.

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Reposted by Christos Argyropoulos MD PhD

Christophe Veltsos @drinfosec.bsky.social · 10d

Latest🎯🧵 by @david.notesforfriends.com: "The Long COVID Denial Zone: When the Pandemic Isn’t “Over” For Everyone"

"America has entered what I call the COVID denial zone, that strange psychological space where millions pretend everything’s back to normal while..."
threadreaderapp.com/thread/19716...

The Long COVID Denial Zone: When the Pandemic Isn’t “Over” For Everyone

I wrote a version of this article and posted it, and pulled it down to correct the reference links. Then our large family, who so far mostly avoided SARS-COV-2 infection, had two infections, and I had to focus on taking care of them. Here is the updated version. Thank you to all those who sent messages of support.

Onward!

America has entered what I call the COVID denial zone, that strange psychological space where millions pretend everything’s back to normal while a growing shadow population struggles with long-term illness.

The Psychology of Mass Denial

Psychology tells us something powerful about human perception: personal experience trumps everything else. This cognitive tendency is called the availability heuristic (mental shortcut), we judge probability and risk based on examples that come easily to mind.

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 10d

@drinfosec.bsky.social very good piece

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Reposted by Christos Argyropoulos MD PhD

AI6YR Ben @ai6yr.m.ai6yr.org.ap.brid.gy · 10d

Ventura County, surging here, take all precautions. One of the locals here... #covid

It takes nine healthy, vigorous humans to keep 60 horses fed and exercised. Today, six of us are sick with COVID-19, influenza A, or both. Three were in bed or at the hospital this afternoon.

It's gnarly here in Ventucky.

#COVIDisNotOver

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 11d

Teaser : movement to, modification at and movement from, of #perl Scalars in the GPU, leveraging https://metacpan.org/release/CHRISARG/Task-MemManager-0.08 to mix #pdl and #gpu calculations & coordinate memory mapping CPU ↔️GPU via #openmp. Functional code […]

[Original post on mastodon.social]

Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 11d

The alien eye-octopus infested sheep asked to count the digits of π scene in episode 7, season 1 of 'Alien Earth' is peak TV and appropriate, yet immediate cause for termination, if one finds themselves micromanaged by their supervisor.

Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 12d

May want to watch SA. This is the single genetic change that has the potential to de attenuate clinical severity of covid to that of NL63 and dramatically reduce the frequency of LC. Or it becomes like the Feline and Porcine corona, and everyone melts from inside 🤣.

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 12d

@musicman There are two questions here: 1) can Tylenol cause autism (possible, just not probable and the magnitude of risk is around 5 to 10% in some analysis but not in others of the same dataset) 2) is Tylenol behind the increase in autism? The answer is most definitely NOT because the numbers […]

Original post on mastodon.social

mastodon.social

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 13d

Mendelian Randomization works if the DAG (from wiki) holds true.
These assumptions have probably held true in <10 studies since the inception of the method, all else is GIGO.

"Z is the genetic variants,
X is the exposure,
Y is the outcome of interest,
U are confounders."

Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 14d

Please give me all your dollars, all your electricity and the water because I can feel the AGI

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 14d

Hear me out: Alien rebooted, but the crew of the USCSS Nostromo is starfaring overmedicated on Tylenol while doping on mRNA and other psychedelic vaccines. Do the Xenomorphs come out autistic after gestating inside the crew?
There are so many possibilities in the acetaminophen/vaxx cosmos.

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 15d

The tylenol-autism vs. vaccines-autism Twitter wars have just begun. Dear Lord, thank you for not rupturing me today so I can watch this reality's version of "The Hunger Games."

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 15d

The tylenol-autism vs. vaccines-autism Twitter wars have just begun. Dear Lord, thank you for not rupturing me today so I can watch this reality's version of "The Hunger Games."