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Communications Biology

@commsbio.nature.com

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An open-access @natureportfolio.bsky.social journal publishing high quality primary research, reviews and commentary in all areas of the biological sciences since 2018. https://www.nature.com/commsbio/

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Communications Biology @commsbio.nature.com · Aug 6

Would you like to participate in the peer review process at Communications Biology? Please fill out this form to express your interest to act as a reviewer📝 We particularly encourage early-career researchers and applicants from underrepresented groups in research. forms.office.com/e/fv22f9aRt5

Communications Biology @commsbio.nature.com · 1d

A novel state-of-the-art approach for absolute binding free energies of RNA-binding small molecules paves the way to the routine use of free-energy simulations in drug discovery targeting RNA systems, reducing failure rates. doi.org/10.1038/s420...

Targeting RNA with small molecules using state-of-the-art methods provides highly predictive affinities of riboswitch inhibitors - Communications Biology

A novel state-of-the-art approach for absolute binding free energies of RNA-binding small molecules paves the way to the routine use of free-energy simulations in drug discovery targeting RNA systems, reducing failure rates.

Communications Biology @commsbio.nature.com · 1d

The authors introduce a reference-guided iterative method to polish modification-disturbed nanopore sequencing basecalls. It is suitable for training biomolecule-specific high-accuracy basecallers empowering the quality control of therapeutic RNAs. doi.org/10.1038/s420...

A reference-guided iterative approach to polish the nanopore sequencing basecalling for therapeutic RNA quality control - Communications Biology

The authors introduce a reference-guided iterative method to polish modification-disturbed nanopore sequencing basecalls. It is suitable for training biomolecule-specific high-accuracy basecallers empowering the quality control of therapeutic RNAs.

Communications Biology @commsbio.nature.com · 1d

A fantastic review on Endozoicomonadaceae, marine, mostly symbiotic bacteria, out now: www.nature.com/articles/s42...

A genomic view of the bacterial family Endozoicomonadaceae in marine symbioses - Communications Biology

This review explores the genomic diversity, ecology, and functional potential of the bacterial family Endozoicomonadaceae in marine symbioses, highlighting their mutualistic to parasitic spectrum and key gaps to be addressed in future research.

Communications Biology @commsbio.nature.com · 1d

Sleep transforms memory: greater REM relative to SWS is associated with reduced item-specific details but enhanced category-level representations, underscoring distinct roles of sleep stages in memory transformation. doi.org/10.1038/s420...

Slow-wave sleep and REM sleep differentially contribute to memory representational transformation - Communications Biology

Sleep transforms memory: greater REM relative to SWS is associated with reduced item-specific details but enhanced category-level representations, underscoring distinct roles of sleep stages in memory transformation.

Communications Biology @commsbio.nature.com · 1d

An intermittent fasting diet regime mitigates retinal cell damage and preserves visual function in a mouse model of age-related macular degeneration.
doi.org/10.1038/s420...

https://doi.org/10.1038/s42003-025-08815-0"

Communications Biology @commsbio.nature.com · 1d

Analyzing Feret diameter is a straightforward way
to assess the quality of unguided brain organoids.
Low-quality brain organoids show a high Feret
diameter, accompanied by a higher proportion of
unintended mesenchymal cells. doi.org/10.1038/s420...

https://doi.org/10.1038/s42003-025-08855-6"

Communications Biology @commsbio.nature.com · 1d

The intricate structure of human heart-forming organoids, including their various tissue components and vascularisation, is studied in its three-dimensionality and at the subcellular level using multiscale X-ray phase-contrast tomography. doi.org/10.1038/s420...

3D histology of human heart-forming organoids by X-ray phase-contrast tomography - Communications Biology

The intricate structure of human heart-forming organoids, including their various tissue components and vascularization, is studied in its three-dimensionality and at the subcellular level using multiscale X-ray phase-contrast tomography.

Communications Biology @commsbio.nature.com · 1d

Pathway-specific biosensors reveal distinct stress responses to photodynamic agents in E. coli, offering mechanistic insight into antimicrobial photodynamic therapy and guiding future therapeutic development. doi.org/10.1038/s420...

Photosensitizer-specific bacterial stress responses in Escherichia coli reveal distinct targets in photoinduced inactivation - Communications Biology

Pathway-specific biosensors reveal distinct stress responses to photodynamic agents in E. coli, offering mechanistic insight into antimicrobial photodynamic therapy and guiding future therapeutic development.

Communications Biology @commsbio.nature.com · 5d

Long non-coding RNAs are identified as non-invasive biomarkers predicting homologous recombination deficiency and PARP inhibitor sensitivity in high-grade serous ovarian cancer, enabling improved precision oncology approaches.

www.nature.com/articles/s42...

@kai82do.bsky.social

Long non-coding RNAs as a biomarker for homologous recombination deficiency and parp inhibitor sensitivity in high-grade serous ovarian cancers - Communications Biology

Long non-coding RNAs are identified as non-invasive biomarkers predicting homologous recombination deficiency and PARP inhibitor sensitivity in high-grade serous ovarian cancer, enabling improved precision oncology approaches.

Communications Biology @commsbio.nature.com · 5d

Sarcolipin expression is transcriptionally induced through a CREB DNA-binding site on its promoter and is suppressed by a site-1 protease-ATF6 axis
www.nature.com/articles/s42...

@cellninja.bsky.social

Site-1 protease is a negative regulator of sarcolipin promoter activity - Communications Biology

Sarcolipin expression is transcriptionally induced through a CREB DNA-binding site on its promoter and is suppressed by a site-1 protease-ATF6 axis.

Communications Biology @commsbio.nature.com · 6d

Seasonally and niche-differentiated diversity of active, dormant and dead microbes in coastal waters and surface sediments

www.nature.com/articles/s42...

Seasonally and niche-differentiated diversity of active, dormant and dead microbes in coastal waters and surface sediments - Communications Biology

Triple-metabarcoding approach reveals niche- and season-specific partitioning of active, dormant, and dead microbial assemblages in tropical coastal ecosystems, challenging DNA-based ecological inferences.

Communications Biology @commsbio.nature.com · 6d

Capture of small scanning ribosomal subunits and
80S ribosomes in mammalian brain tissues provides insights into translation initiation and the role of scanning in
regulating cell and transcript-specific translation.

www.nature.com/articles/s42...

Transcriptome-wide mapping of small ribosomal subunits elucidates scanning mechanisms of translation initiation in the mammalian brain - Communications Biology

Capture of small scanning ribosomal subunits and 80S ribosomes in mammalian brain tissues using ribosome complex profiling provides insights into translation initiation and the role of scanning in regulating cell–and transcript-specific translation.

Communications Biology @commsbio.nature.com · 7d

New review on linguistic neural decoding with deep learning www.nature.com/articles/s42...

Progress, challenges and future of linguistic neural decoding with deep learning - Communications Biology

This review summarizes the current progress on linguistic neural decoding from a machine learning perspective, focusing on the extraction and generation of text and speech information from brain activity patterns.

Communications Biology @commsbio.nature.com · 7d

Now open for submissions: The new @natureportfolio.nature.com cross-journal biosensing collection, with @natcomms.nature.com Nature Biomedical Engineering and the new Nature Biosensors - and of course Scientific Reports: www.nature.com/collections/...

With this cross-journal Collection, the editors of Communications Biology, Nature Biomedical Engineering, Nature Sensors, Nature Communications, and ...

Communications Biology @commsbio.nature.com · 7d

Due to the large success of the @natureportfolio.nature.com cross-journal Immune cell engineering for cancer therapy collection, we set up a new edition. Now open for submission, the 2026 edition, with @natcomms.nature.com @commsmed.nature.com: www.nature.com/collections/...

Immune cell engineering for cancer therapy 2026

With this Collection, a partnership between Nature Communications, Communications Medicine, Communications Biology, and Scientific Reports, we welcome ...

Reposted by Communications Biology

Jean-Philip Piquemal @jppiquem.bsky.social · 7d

#compchem #compbio Happy to be part of this new paper just published in @commsbio.nature.com : "Targeting RNA with Small Molecules using State-of-the-Art Methods Provides Highly Predictive Affinities of Riboswitch Inhibitors."
www.nature.com/articles/s42...
@qubit-pharma.bsky.social

Reposted by Communications Biology

Nature Climate Change @natclimate.nature.com · 8d

🚨 We are hiring - Nature Climate Change is recruiting for a full time editor to join our team. This is a great opportunity for a PhD trained researcher to move into editorial. Applications close 23 October
www.nature.com/naturecareer...

Associate or Senior Editor, Nature Climate Change - Shanghai (CN) /Beijing/New York job with Springer Nature Ltd | 12845336

Job Title: Associate or Senior Editor (Nature Climate Change) Organisation: Nature Portfolio Location: Shanghai, Beijing, New York, New Jersey - hy...

Communications Biology @commsbio.nature.com · 12d

Polygenic scores and partitioned polygenic scores related to insulin resistance derived in multiancestry populations show distinct association with neurological outcomes
@sarnowskichloe.bsky.social
www.nature.com/articles/s42...

Association of genetic scores related to insulin resistance with neurological outcomes in ancestrally diverse cohorts from the Trans-Omics for Precision Medicine (TOPMed) program - Communications Biology

Polygenic scores and partitioned polygenic scores related to insulin resistance derived in multiancestry populations show distinct association with neurological outcomes

Communications Biology @commsbio.nature.com · 12d

Individual differences in the expression of an insulin receptor gene network in the prefrontal cortex and striatum influence the risk of visceral fat accumulation and metabolic syndrome, especially in women exposed to early-life stress www.nature.com/articles/s42...

Brain insulin receptor gene network shapes risk for metabolic disease after early-life stress in women - Communications Biology

How the brain responds to early-life stress may shape future health: individual differences in the expression of an insulin receptor gene network in the prefrontal cortex and striatum influence the risk of visceral fat accumulation and metabolic syndrome, especially in women exposed to early-life stress.

Communications Biology @commsbio.nature.com · 12d

Sarcolipin expression is transcriptionally induced through a CREB DNA-binding site on its promoter and is suppressed by a site-1 protease-ATF6 axis. @cellninja.bsky.social doi.org/10.1038/s420...

Communications Biology @commsbio.nature.com · 13d

conformational change in the actin-binding domain of α-catenin is required for adherens junction maturation as researchers from @uni-muenster.de show
www.nature.com/articles/s42...

A conformational change in α-catenin’s actin-binding domain governs adherens junction maturation - Communications Biology

A FRET-based biosensor reveals a conformational change in the actin-binding domain of α-catenin during the maturation of epithelial adherens junctions.

Communications Biology @commsbio.nature.com · 13d

The Project on Poverty in Neuroblastoma Evolution team from @umich.edu published a study on how socioeconomic stressors (here, food insecurity) can have an influence on cancer dynamics www.nature.com/articles/s42...

Food insecurity impacts neuroblastoma pathogenesis in murine xenograft tumor models - Communications Biology

Mechanistic modeling of food insecurity reveals how chronic social stress accelerates neuroblastoma progression through tumor-intrinsic and microenvironmental changes in stress signaling.

Communications Biology @commsbio.nature.com · 15d

A new study reveals distinct neural substrates of apathy,
effort and reward valuation in humans www.nature.com/articles/s42...

Fronto-motor circuits linked to effort-based decision-making and apathy in healthy subjects - Communications Biology

Multimodal quantification of structural and effective connectivity in fronto–motor circuits reveals distinct neural substrates of apathy, effort and reward valuation in humans, highlighting potential neuromodulation targets for motivational deficits.

Communications Biology @commsbio.nature.com · 15d

New research on extracellular vesicles in ovarian cancer from Nagoya, Japan - www.nature.com/articles/s42...

Overcoming platinum-resistant ovarian cancer targeting the activated JAK-STAT pathways via extracellular vesicles - Communications Biology

Peritoneal mesothelial cell-derived extracellular vesicles provide a new mechanism for platinumresistant ovarian cancer through the enrichment of miR-135a-5p, which activates JAK-STAT signaling and suggests JAK as a key therapeutic target.

Communications Biology @commsbio.nature.com · 15d

Single-cell spatial transcriptomics reveals that CAFs at the invasive front of colorectal tumors induce pro-invasive changes in budding cancer cells - research from - among others - @au.dk www.nature.com/articles/s42...

Cancer-associated fibroblasts shape the formation of budding cancer cells at the invasive front of human colorectal cancer - Communications Biology

Single-cell spatial transcriptomics reveals that CAFs at the invasive front of colorectal tumors induce pro-invasive changes in budding cancer cells, characterized by an 11-gene signature linked to metastasis and poor prognosis.