#ComplexPortal #EMBLEBI #PlantScience #Ecology #UKCEH #Ammonia #Transporterproteins

🌿 Why it matters
• Excess NH₄⁺ disrupts growth and cellular balance
• Species differ in ammonium tolerance, influencing biodiversity
• Human-driven nitrogen favours ammonium-tolerant species

💡 Plants aren’t passive nitrogen absorbers-they actively regulate uptake to balance nutrition and stress.

#ComplexPortal #EMBLEBI #PlantScience #Ecology #UKCEH #Ammonia #Transporterproteins

🌿 Why it matters
• Excess NH₄⁺ disrupts growth and cellular balance
• Species differ in ammonium tolerance, influencing biodiversity
• Human-driven nitrogen favours ammonium-tolerant species

💡 Plants aren’t passive nitrogen absorbers-they actively regulate uptake to balance nutrition and stress.

This protects plants from ammonium toxicity and shapes species fitness across different nitrogen environments.
Learn more via the Complex Portal: tinyurl.com/yn9zzfav

Registration is free but essential: tinyurl.com/4v3jf4e9

Speakers: Susie H. and Eliot Ragueneau

#Bioinformatics #IntAct #Modelling #BiologicalNetworks #Cytoscape

Upon her retirement from EMBL-EBI, we thank Sandra for her dedication and foundational work on important open data resources including:

UniProt
Complex Portal @complexportal.bsky.social
Gene Ontology @geneontology.bsky.social
IntAct @intact-ebi.bsky.social
InterPro @interprodb.bsky.social

#ComplexPortal #PDBe #StructuralBiology #Bioinformatics #ProteinComplexes #LifeSciencesData #EMBL

Follow the link to uncover:

🧩 what the complex does in the cell
🔄 pathways it participates in (Reactome)
🧬 and curated disease links (EFO, MONDO, OMIM).

PDBe gives the structure — the Complex Portal adds the biology. Together they tell the full story: structure → function → system.

#ComplexPortal #PDBe #StructuralBiology #Bioinformatics #ProteinComplexes #LifeSciencesData #EMBL

Follow the link to uncover:

🧩 what the complex does in the cell
🔄 pathways it participates in (Reactome)
🧬 and curated disease links (EFO, MONDO, OMIM).

PDBe gives the structure — the Complex Portal adds the biology. Together they tell the full story: structure → function → system.

🧫 Explore the curated dataset in IntAct ➡️ tinyurl.com/candidalysin

🎨IntAct Cytoscape visualisation:
Candida albicans ECE1 peptides (orange) and their human protein targets (blue)

#IntActEBI #Interactome #EMBL

Let’s make your science more FAIR - Findable, Accessible, Interoperable, and Reusable.
#Biocuration #FromBenchToDatabase #FAIRdata #ProteinInteractions #EMBL-EBI #IntAct-EBI #OpenScience #UniProt #DataMatters

📥 Submit your data here:
🔹 IntAct: tinyurl.com/zzrcx742

Want your PPI or structural data to make an impact?
✅ Use Identifierss
✅ Include structured tables (e.g. Niri et al. 2021 - PMID: 34197713)
✅ Submit to EMBL-EBI's data resources - IntAct

👉 See Niri’s dataset in IntAct:
tinyurl.com/yp8ddheh

🔗 Explore CPX-6502 (tinyurl.com/wm9vz558) via the @emblebi Complex Portal - mapping all biologically functional protein complexes.

#GlobalPNHAwarenessDay #PNH #RareDisease #GPIAnchors #ComplementSystem #GpiGnT #ComplexPortal #EMBLEBI

See also @wojtekgalej.bsky.social and
tinyurl.com/3sfthabb

#MinorSpliceosome #RNAsplicing #snRNP #U12Introns

🕸️ Explore the interactome on the IntAct tinyurl.com/35922511.

🆕 New feature: You can now group nodes by orthology 🧩 — stay tuned for more details!

#Immunology #Proteomics #MolecularInteractions #HumanImmuneSystem