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Royal Society of Chemistry @rsc.org · 5d

🏆We’ve transformed how we recognise excellence in chemistry to ensure our prizes better reflect today’s science culture.

Our new Reshaping Recognition report to learn how we have modernised our 156-year-old #RSCPrizes portfolio!

Explore the changes: buff.ly/vcxBBHE #ChemSky

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Conway Group @conway-group.bsky.social · 13d

Hypoxia-activated PROTACs (HAP-TACs) are online in @jacs.acspublications.org (pubs.acs.org/doi/10.1021/...)! Collborative work with Ester Hammond (@hammond-lab.bsky.social). Congrats to Marta Serafini, Sophie Twigger, George Delfas, Max Mallerman, Elliot Bailey & Ewen Calder (@ecalder.bsky.social).

Indolequinone-Based Hypoxia-Activated Proteolysis Targeting Chimeras Selectively Degrade BRD4 in Hypoxic Cancer Cells

Proteolysis targeting chimeras (PROTACs) have helped to establish proximity induction as an exciting strategy in drug discovery, and there are multiple clinical trials focused on this modality. Howeve...

pubs.acs.org

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Conway Group @conway-group.bsky.social · Aug 7

Great to see you today @sebvidalchem.bsky.social ! And great to welcome you home to UCLA Chemistry & Biochemistry (@uclacb.bsky.social)

Sebastien Vidal @sebvidalchem.bsky.social · Aug 7

Today's visit UCLA hosted by @conway-group.bsky.social Ken Houk and Mike Jung was a real "return to the future" for me and bringing so many memories from my 2000-03 postdoc with Fraser Stoddart
Missing you Fraser 😪
Met students from the Garg Lab located in my former lab, thanks guys!

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Sebastien Vidal @sebvidalchem.bsky.social · Aug 3

Where am I?
#ChemSky

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Conway Group @conway-group.bsky.social · Jul 2

Our pre-print on the development of bivalent ligands for the TRIM24 bromodomain & PHD is now online chemrxiv.org/engage/chemr...

Congratulations to the authors: Michael Platt, Ekaterina Kot, Louise Martin, Antoine Wallabrègue, Liwen Song, Alistair Boyd, Lizbé Koekemoer, & @hammond-lab.bsky.social

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ChemRxiv @chemrxiv.org · Jul 1

Hello #ChemSky! We're the open preprint server for the global chemistry community and we're glad to be here.

Follow along as we share exciting preprints and engage with the community. Learn more about us: chemrxiv.org

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Conway Group @conway-group.bsky.social · Jul 1

Many congratulations to Sarah Singleton for passing her qualifying exams @uclacb.bsky.social and officially becoming a PhD candidate! Many thanks to her committee members, Profs Backus, Clarke, and Mikkola for their advice and wisdom.

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Conway Group @conway-group.bsky.social · Jun 21

As the active PROTAC is revealed selectively in hypoxia, POI (BRD4) degradation occurs mainly in hypoxia. This technology has the potential to give PROTACs that degrade selectively in hypoxic tumors.

This is collaborative work with @hammond-lab.bsky.social - congratulations to all of the authors.

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Conway Group @conway-group.bsky.social · Jun 21

Our pre-print on hypoxia-activated PROTACs (HAP-TACs) is now on ChemRvix: chemrxiv.org/engage/chemr...

We used the indolequinone bioreductive group to protect VHL- or CRBN-recruiting BRD4 degraders rendering them inactive. This group is removed selectively in hypoxia, revealing the active PROTAC.

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UCLA Department of Chemistry & Biochemistry @uclacb.bsky.social · May 29

The UCLA Department of Chemistry & Biochemistry is excited to welcome Dr. Antonio Tinoco Valencia (Harvard), who will join the @ucla faculty as an Assistant Professor on July 1, 2025. www.chemistry.ucla.edu/news/welcomi...

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New Phytologist @newphyt.bsky.social · May 12

#Hypoxia-activated fluorescent probes as markers of oxygen levels in plant cells and tissues

#PlantScience by Monica Perri, et al.

📖 nph.onlinelibrary.wiley.com/doi/10.1111/...

@emilyflashman.bsky.social @daanweits.bsky.social @conway-group.bsky.social @hammond-lab.bsky.social

Bioreductive hypoxia-responsive chemical probes show fluorescence in hypoxic tissue of Arabidopsis.

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Danielle L. Schmitt 🔬 @schmittwitt.bsky.social · Apr 25

Thank you to the Editors of ACS Bio & Med Chem Au & @conway-group.bsky.social for nominating me. I appreciate the support so early in my career. My lab has some very exciting things in the works I can’t wait to share! 🌟

UCLA Department of Chemistry & Biochemistry @uclacb.bsky.social · Apr 25

🥳 Congratulations to Prof. Danielle Schmitt
@schmittwitt.bsky.social on being named a 2024 Rising Star by ACS's Bio & Med Chem Au. This prestigious award recognizes emerging global leaders whose research is making a lasting impact in the natural sciences. www.chemistry.ucla.edu/news/profess...

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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · Apr 23

Everyone please read and act! 👇

Jeremy Berg @jeremymberg.bsky.social · Apr 23

ACTION ITEM-----ACTION ITEM

Implementation of Schedule F

This is what a lot of us have been worried about.

This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.

BUT THERE IS A COMMENT PERIOD...

1/n

the word alert is in a purple circle

ALT: the word alert is in a purple circle

media.tenor.com

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Conway Group @conway-group.bsky.social · Apr 21

Many congratulations to Tanya D'Souza, an undergraduate researcher in our lab, who has been awarded a Summer Undergraduate Research Fellowship to continue her research across the summer! Many thanks to the ACS @organicdivision.org for the award of this fellowship and to Genentech for sponsorship.

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Organic Division of the ACS @organicdivision.org · Apr 18

The Division of Organic Chemistry (DOC) congratulates the sixteen 2025 DOC Summer Undergraduate Research Fellowship (SURF) awardees and gratefully acknowledges the generous sponsors.

zurl.co/x1kZh

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UCLA Department of Chemistry & Biochemistry @uclacb.bsky.social · Apr 14

In a recent blog, Prof. Osvaldo Gutierrez shares his journey from undocumented UCLA student to chemistry professor and offers advice to a new generation of Bruins.
chemistry.ucla.edu/news/rancho-...

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Conway Group @conway-group.bsky.social · Apr 11

My kids were taught science by the granddaughter of Hans Krebs. When she rode her bike to work I was always amused by seeing the Krebs’ cycle.

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Conway Group @conway-group.bsky.social · Mar 26

Was very pleased to get in a couple of early morning #ChemistsWhoRun runs at #ACSSpring2025 , one with Andrew Scholte and John Gavenonis, and one with Will Pomerantz (@fewill26.bsky.social) catching up on all things epigenetics!

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Jordan Meier @doc-jlmeier.bsky.social · Mar 24

Today there are two symposia at the ACS in honor of Peter Dervan (11AM & 5PM).

Although I can't be there to celebrate, I wanted to share a few reflections on my time in his lab (2009-2012) and the impact he's had on me as a scientist.

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ChemRxiv Bot @chemrxivbot.bsky.social · Mar 14

A novel photoaﬃnity probe for analysing the phosphatdylinositol 5-phosphate interactome

Authors: Glen Brodie, Ahmed Sayed, Sarah Kreuz, Wolfgang Fischle, Stuart Conway
DOI: 10.26434/chemrxiv-2025-llnc4

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Sherry Pagoto, PhD @drsherrypagoto.bsky.social · Mar 12

New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024.

That's not to mention the countless lives that biomedical research has saved.

Show me a better investment than that.
www.forbes.com/sites/michae...

NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report

National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.

www.forbes.com

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Conway Group @conway-group.bsky.social · Mar 12

Yes super disappointing.

Conway Group @conway-group.bsky.social · Mar 12

Not sure. Where would I look?

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Conway Group @conway-group.bsky.social · Mar 11

The NIH "Fellowships: Topics in biochemistry and chemical biology" Study Section scheduled for March 20th/21st has just been postponed...

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Alt NIH Bluesky 🧪 @altnih4science.bsky.social · Mar 8

We now have a Twitter account, to reach people who are not on bluesky—and to help get them here.

If you still have a Twitter account please follow us there, and ask others to follow too.
x.com/altnih4science

x.com

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