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The Coster lab 🧬🔬

@costerlab.bsky.social

510 followers 200 following 36 posts

Based at the Institute of Cancer Research in London, we study how DNA affects its own replication. www.CosterLab.com

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The Coster lab 🧬🔬 @costerlab.bsky.social · Sep 3

Congrats Alexis! Fantastic news and well deserved 🎉

The Coster lab 🧬🔬 @costerlab.bsky.social · Sep 3

Some repeats and structure-forming sequences are indeed difficult to clone, not because they are toxic, but because they are genetically unstable. Examples are AT and CGG repeats. If a sequence is problematic, cloning efficiency will be low, but clones you do get will have deletions in that area.

The Coster lab 🧬🔬 @costerlab.bsky.social · Sep 2

Are you having issues with a plasmid or are you trying to introduce a toxic sequence on purpose?

The Coster lab 🧬🔬 @costerlab.bsky.social · Sep 1

🎉 Congrats Mathew and Mike! Great to finally see this out. A fantastic tool for the replication community and beyond 👏

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The Coster lab 🧬🔬 @costerlab.bsky.social · Jul 9

Congrats Hasan. Well deserved 🎉😁

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The Coster lab 🧬🔬 @costerlab.bsky.social · Jul 3

Very cool to see MCM loading in action and with such detail. Years of genetic, biochemical and structural work from many labs distilled into a beautiful animation 🧬👍

The Coster lab 🧬🔬 @costerlab.bsky.social · Jun 23

Had a fun day in the sun, hosting the lab for a BBQ
🍔🥗🍺☀️
Great food and company 😁
I am so grateful and happy to work with such lovely people 😎

The Coster lab 🧬🔬 @costerlab.bsky.social · Jun 19

Congrats Stephen 🎉🎉🎉

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The Coster lab 🧬🔬 @costerlab.bsky.social · Jun 13

Congrats Puck and Koichi 🎉 Super exciting G4 biology 🧬

The Coster lab 🧬🔬 @costerlab.bsky.social · Jun 12

New lab member joining is a great excuse to eat out and take a new lab photo 🎉🍜📷

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The Coster lab 🧬🔬 @costerlab.bsky.social · Jun 12

Welcome to our newest lab member - Ellie Wright.
She did her PhD with Matt Neale and will lead data analysis and omics in the lab as a Higher Scientific Officer 💻🧬

Reposted by The Coster lab 🧬🔬

Adrien Leger @adrienleger.bsky.social · Jun 2

🚨 We’re hiring ! 🚨
Join our cutting-edge research team as a molecular biologist at @nanoporetech.com HQ in Oxford.
Perfect for a fresh PhD or MSc with a couple of years’ experience. Work at the interface of chemistry, molecular/synthetic biology and AI

👉 ejnh.fa.em2.oraclecloud.com/hcmUI/Candid...

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The Coster lab 🧬🔬 @costerlab.bsky.social · Jun 5

Congrats Tanmay 🎉🎉

The Coster lab 🧬🔬 @costerlab.bsky.social · Mar 29

Great to have two lab alumni visit - Manolo @dazamartinlab.bsky.social and Sophie. Congrats to Manolo's son Javier on his first birthday 🎂🎊

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The Coster lab 🧬🔬 @costerlab.bsky.social · Mar 13

📷 New lab photos 😎
Still undecided as to which one is better... But we all look so happy 😏

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The Coster lab 🧬🔬 @costerlab.bsky.social · Mar 13

Had a fantastic day at the Genome Damage and Stability Center in Sussex. Lovely to see Brighton and have stimulating discussions with colleagues. Thanks Laurence Pearl for the invitation!

The Coster lab 🧬🔬 @costerlab.bsky.social · Mar 6

Congrats Dirk and team! Great work and good to finally see it out!

The Coster lab 🧬🔬 @costerlab.bsky.social · Jan 24

🎉🔬 The lab has expanded! Today we celebrated the joining of Adi and Maria, two postdocs, with great Vietnamese food 🍽️

The Coster lab 🧬🔬 @costerlab.bsky.social · Dec 11

Congrats Alessandro!

The Coster lab 🧬🔬 @costerlab.bsky.social · Dec 6

Thanks Francesca!

The Coster lab 🧬🔬 @costerlab.bsky.social · Dec 6

Thanks Christian!

The Coster lab 🧬🔬 @costerlab.bsky.social · Dec 6

Thanks Alessandro!

The Coster lab 🧬🔬 @costerlab.bsky.social · Dec 6

Thanks Annabel!

The Coster lab 🧬🔬 @costerlab.bsky.social · Dec 6

Thanks Martijn!

The Coster lab 🧬🔬 @costerlab.bsky.social · Dec 6

Thanks Colin!