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ASAP CRN Team Cragg @craggasap.bsky.social · 27d

📣 New preprint alert 📣

A new collaborative study from @meletis.bsky.social and @jakobssonasap.bsky.social on mapping the molecular changes in the mouse and human striatum in #Parkinsons! Congratulations to Marta Graziano and Ioannis Mantas for spearheading this fantastic work!

#OpenScience

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ASAP CRN Team Cragg @craggasap.bsky.social · Sep 4

@stephcragg.bsky.social @oxforddpag.bsky.social

ASAP CRN Team Cragg @craggasap.bsky.social · Sep 4

Meet Tony Barbay, our new MRC-funded Postdoctoral Researcher at Cragg Lab! He will explore the role of astrocytes as neuromodulators in the striatum in health and PD. We look forward to working with you!

Learn more: www.dpag.ox.ac.uk/team/tony-ba...

#Parkinsons #astrocytes #The_MRC #MeetOurTeam

Tony Barbay

PhD Tony Barbay - Postdoctoral Research Scientist

www.dpag.ox.ac.uk

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ASAP CRN Team Cragg @craggasap.bsky.social · Aug 29

📣The Wade-Martins Lab is hiring 📣

Are you interested in developing novel biomarkers and testing therapeutic compounds using iPSC-derived dopamine neurons from PD patients? Join us as a Research Assistant at the University of Oxford.

Deadline is noon (UK time) on Sept 5th!

bit.ly/4lURYW9

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Reposted by ASAP CRN Team Cragg

Coalition for Aligning Science @aligningscience.com · Aug 7

We're kicking off our new series: Initiative Spotlight 🔦 starting with Aligning Science Across Parkinson's (ASAP)!

@asapresearch.parkinsonsroadmap.org aims to speed discovery and drive progress toward a #ParkinsonsDisease cure through collaboration and open science.

Learn more: bit.ly/3Ys7sIo

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ASAP CRN Team Cragg @craggasap.bsky.social · Aug 29

@wademartinslab.bsky.social @asapresearch.parkinsonsroadmap.org

ASAP CRN Team Cragg @craggasap.bsky.social · Aug 29

In case you missed it, be sure to watch July's instalment of the Discover ASAP!

Ricardo Márquez Gómez from Wade-Martins Lab discussed their scalable microfluidic platform that enables the study of human neuron microcircuitry, connectivity, and regeneration in vitro 🔬

#OpenScience #PD #iPSCs

Aligning Science Across Parkinson's @asapresearch.parkinsonsroadmap.org · Jul 28

This month’s Discover ASAP features Ricardo Márquez Gómez of @craggasap.bsky.social, discussing a fluid-wall microfluidic platform to model human corticostriatal circuits 🧪

This platform enables axon studies, long-term culture, & scalable testing for #Parkinsons.

📺 youtu.be/dutY_mxext4

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ASAP CRN Team Cragg @craggasap.bsky.social · Aug 29

@stephcragg.bsky.social @wademartinslab.bsky.social

ASAP CRN Team Cragg @craggasap.bsky.social · Aug 27

Fantastic work spearheaded by @safabouabid.bsky.social from Mark Howe Lab!

Aligning Science Across Parkinson's @asapresearch.parkinsonsroadmap.org · Aug 25

CRN Team Cragg used array photometry in mice to reveal a topography of opposing changes in ACh release across distinct striatal regions. Reward prediction error encoding was localized to specific phases of ACh dynamics in anterior dorsal striatum.

🔗 Read the full #publication: bit.ly/3JjqQCE

Opposite ACh changes with learning at cue and reward are signal component selective and spatially concentrated in the anterior dorsal striatum.

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ASAP CRN Team Cragg @craggasap.bsky.social · Aug 27

Check out Katherine Brimblecombe's news article on outreach activities!

Katherine reflects on how her outreach work with primary school kids has led to changes in the way she thinks about science communication.

#SciComm #ScienceOutreach #WomenInSTEM #STEM

Outreach: How Science Week's 2025 theme made me reflect on how I talk about science (by Dr Katherine Brimblecombe)

Science week 2025 theme: Change and adapt

www.dpag.ox.ac.uk

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ASAP CRN Team Cragg @craggasap.bsky.social · Aug 22

📣 New publication alert 📣

Check out our collaborative review on axonal molecular and circuit mechanisms governing dopamine exocytosis in health and PD. Congratulations to Kathryn Todd from Cragg Lab and Kaitlyn Cramb from Wade-Martins Lab for spearheading this publication!

New insights into axonal regulators of dopamine transmission in health and disease

Dopamine release in the striatum is credited with being critical to the selection and learning of motivated actions and outcomes. Dysregulation of str…

www.sciencedirect.com

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ASAP CRN Team Cragg @craggasap.bsky.social · Aug 22

@stephcragg.bsky.social @lintianphd.bsky.social @yulonglilab.bsky.social @asapresearch.parkinsonsroadmap.org

ASAP CRN Team Cragg @craggasap.bsky.social · Aug 22

Are you at the ISN-ASN Meeting held in New York this week?

Don't miss out the talk from our very own Steph Cragg this Friday from 3 to 5 pm EDT! The "Flowing Neurochemicals in the Brain" symposium is being chaired by CRN members Yulong Li and Lin Tian.

S27 T#2 Flowing Neurochemicals in the Brain - ISN

Room: Hall C – Parallel 2 Chair: Yulong Li (China) Lin Tian (United States) Designs, applications and limitations of genetically encoded indicators in imaging neurotransmitters in vivo Stephanie Cragg...

www.neurochemistry.org

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ASAP CRN Team Cragg @craggasap.bsky.social · Aug 19

📣 A new book announcement 📣

The Handbook of #dopamine, from Steph Cragg (@stephcragg.bsky.social) and Mark Walton, and a cover illustration from the talented Lucille Duquenoy from Cragg Lab, is available to pre-order now!

OxfordDPAG @oxforddpag.bsky.social · Aug 12

We have an exciting new book to announce! www.dpag.ox.ac.uk/news/oxford-...

Oxford Professors Cragg and Walton celebrate publication of new book, The Handbook of Dopamine

www.dpag.ox.ac.uk

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ASAP CRN Team Cragg @craggasap.bsky.social · Aug 19

Congratulations to Shinil Raina, who left her position as a RA in the Cragg Lab to take up an MRC iCase funded DPhil position in the Yeo lab at University of Cambridge. We will miss you dearly and wish you the best of luck on your endeavours!

Who will win the best poster awards for our team now?

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ASAP CRN Team Cragg @craggasap.bsky.social · Jul 7

A new #MRC CoRE will focus on developing brain stimulation devices to treat conditions such as Parkinson’s, dementia, stroke and childhood epilepsy.

🎉Many congratulations to our co-PI, Professor Peter Magill, who will be the Director of the MRC CoRE in Restorative Neural Dynamics! 🎉

Oxford to lead new £50m MRC Centre to develop brain stimulation

A new Medical Research Council Centre of Research Excellence (MRC CoRE) aims to develop brain stimulation devices to treat conditions such as Parkinson’s, dementia, stroke and childhood epilepsy.

www.ox.ac.uk

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ASAP CRN Team Cragg @craggasap.bsky.social · Jun 30

Find more details about the 2025 Oxford Parkinson's Research Day: www.dpag.ox.ac.uk/opdc/oxford-...

Oxford Parkinson's Research Day - Tuesday 3 June 2025

www.dpag.ox.ac.uk

ASAP CRN Team Cragg @craggasap.bsky.social · Jun 30

Read this blog post on the highlights from the 2025 CRN Collaborative Meeting: parkinsonsroadmap.org/news/highlig...

Charting New Waters in Parkinson’s Research: Highlights From the 2025 CRN Collaborative Meeting

ASAP's 2025 Collaborative Meeting welcomed representatives from our 35 CRN teams to share impactful findings on the PD landscape, promote the cross-fertilization of ideas, and provide opportunities to...

parkinsonsroadmap.org

ASAP CRN Team Cragg @craggasap.bsky.social · Jun 30

Team Cragg was out in full-force at the 2025 Oxford Parkinson's Research Day hosted by OPDC earlier this month!

📣 Shoutout to our presenters, Kaitlyn Cramb, Katherine Brimblecombe, Ollie Curry, Rasha Elghaba, and Camille Loiseau, for sharing their fantastic work with the PD community! 📣

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ASAP CRN Team Cragg @craggasap.bsky.social · Jun 30

Congratulations to our Project Manager Cláudia Mendes for being nominated as ASAP #OpenScience Champion this month!

Claudia is deeply committed to make science more open and transparent at all stages of scientific discovery. Thank you for her hard work for making our articles fully ASAP-compliant!

Aligning Science Across Parkinson's @asapresearch.parkinsonsroadmap.org · Jun 26

🎊 This month, we are celebrating Claudia Mendes from @craggasap.bsky.social and Julianna Tomlinson from CRN Team Schlossmacher as our June #OpenScience Champions for user testing the new Hub Compliance Submission System and providing feedback. Thank you both for your dedication to open science.

Headshots of Claudia Mendes (Team Cragg) and Julianna Tomlinson (Team Schlossmacher) on a light blue background. The Open Science and ASAP logos are also present.

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ASAP CRN Team Cragg @craggasap.bsky.social · Jun 23

@natcomms.nature.com

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ASAP CRN Team Cragg @craggasap.bsky.social · Jun 23

A new publication from Howe Lab is out in Nature Comms examining how #acetylcholine dynamics shape region-specific plasticity to gate learning and promote extinction. Congrats to Safa, Mai-Anh, and the rest of the authors for a fantastic #openscience paper!

@asapresearch.parkinsonsroadmap.org

Distinct spatially organized striatum-wide acetylcholine dynamics for the learning and extinction of Pavlovian associations - Nature Communications

Functional roles of natural acetylcholine (ACh) dynamics are not fully understood. This study reveals dynamic changes in ACh release across the mouse striatum during learning and extinction, identifyi...

doi.org

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ASAP CRN Team Cragg @craggasap.bsky.social · Jun 12

🎉Many congratulations to Dr. Bethan O'Connor, and Dr. Lucille Duquenoy from the Cragg Lab who recently passed their DPhil Vivas 🎉

Your hard work and effort has paid off, and Team Cragg is proud of all you have accomplished!

@stephcragg.bsky.social @oxforddpag.bsky.social

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ASAP CRN Team Cragg @craggasap.bsky.social · May 8

@stephcragg.bsky.social @socneuro.bsky.social

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ASAP CRN Team Cragg @craggasap.bsky.social · May 8

The Cragg lab is going to NeuroFrance 2025 in Montpellier!

Our very own PI Steph Cragg will give a plenary lecture on astrocytes, dopamine and acetylcholine, and lab members Simon Bossi and Lucille Duquenoy will present posters on their impressive work. Come say hi!

www.neurosciences.asso.fr/SN25/

Home - NeuroFrance 2025

Every two years, neuroscientists from all over France get together to share their research, discover new ideas and exchange views and opinions.

www.neurosciences.asso.fr

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