Csaba Orban
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csabaorban.bsky.social
Csaba Orban
@csabaorban.bsky.social
87 followers 98 following 1 posts
neuroscience, physiology, resting state fMRI
Posts Replies Media Videos
Reposted by Csaba Orban
fmrib-steve.bsky.social
Preprint on PANDORA by Aslan Abivardi:

A massive archive of UK Biobank brain imaging from 82K subjects. For each of 98 sub-modalities (e.g., FA from dMRI), the images are collated into a convenient subjectsXvoxels HDF5 file.

pages.fmrib.ox.ac.uk/pandora/web/

www.medrxiv.org/content/10.6...
January 7, 2026 at 8:15 AM
Reposted by Csaba Orban
weigangcui.bsky.social
Check out our new work on the relationship between glioma and system-level functional networks! We identify that nearly all gliomas localize within a common brain functional network, Action-Mode Network (AMN) .

biorxiv.org/content/10.64898/2026.01.05.697608v1
January 6, 2026 at 7:25 AM
Reposted by Csaba Orban
benjaminkay.bsky.social
This is your brain on Ritalin. Got your attention? Stimulant medications like Ritalin (methylphenidate) do, but not in the way you might think. They don't act directly on the brain’s attention systems! Find out what's really happening in @cellpress.bsky.social. doi.org/10.1016/j.ce...
December 24, 2025 at 4:46 PM
Reposted by Csaba Orban
ariellekeller.bsky.social
Our paper on the ☀️ "summer slide" 🛝 is out now @pnas.org!
www.pnas.org/doi/10.1073/...
Summer slide is a replicable phenomenon across diverse datasets that's more than "forgetting" school material in vacation months, but effects of socioeconomic inequality are ➡️ 7x bigger! ⬅️
#PsychSciSky #DevPsy
🧵👇
December 16, 2025 at 5:56 PM
Reposted by Csaba Orban
plosbiology.org
How do internal bodily rhythms influence #brain activity & motor function? @tahnee-engelen.bsky.social &co show that #cardiac, #respiratory & #gastric rhythms independently modulate motor excitability, revealing distinct #interoceptive profiles across individuals @plosbiology.org 🧪 plos.io/4nMtpLT
Top: Experimental set up. Single pulses of TMS were applied to the hand area of the right primary motor cortex with an inter-pulse interval randomized between 6 and 10 s. Simultaneously, the neuronavigated coil position (yellow), electrocardiogram (red), respiratory signal (blue), electrogastrogram (green), and electromyography from the left hand (gray) were recorded. The figure shows traces of a 20-s time segment from one participant of the cardiac (raw), respiratory (filtered), gastric (filtered), and EMG (raw) signals. The experimental measure was the Motor Evoked Potential amplitude measured on a hand muscle (first dorsal interosseous), analyzed against the phase of the cardiac, respiratory, and gastric rhythms. Note that the three rhythms have very different periods (~1 s for the heart, ~ 5 s for respiration, and ~20 s for the gastric rhythm). Bottom: Artwork illustrating how rhythms of the internal organs interact with the moment-to-moment fluctuations observed in corticospinal motor excitability. Image depicts an outline of a brain with representations of the three rhythmic organs influencing the motor system: the heart, lungs, and stomach. Image credit: Tahnée Engelen.
November 13, 2025 at 10:17 AM
Reposted by Csaba Orban
nature.com
Nature research paper: Adenosine signalling drives antidepressant actions of ketamine and ECT

go.nature.com/3Ln1gh6
Adenosine signalling drives antidepressant actions of ketamine and ECT - Nature
Adenosine signalling is identified as the central mechanism of action of the antidepressant effects of ketamine and electroconvulsive therapy, and newly developed analogues of ketamine exhibit improved antidepressant efficacy with reduced side effects.
go.nature.com
November 7, 2025 at 6:27 PM
Reposted by Csaba Orban
bttyeo.bsky.social
Preprint is now published! doi.org/10.1002/hbm....

Thanks to co-authors @chen-zhang.bsky.social @anlijuncn.bsky.social @csabaorban.bsky.social
November 4, 2025 at 12:35 AM
Reposted by Csaba Orban
bttyeo.bsky.social
Preprint is now published: doi.org/10.1002/hbm....

Special thanks to co-authors @twktan.bsky.social @kimnganngt.bsky.social @csabaorban.bsky.social
November 4, 2025 at 12:32 AM
Reposted by Csaba Orban
imagingneurosci.bsky.social
Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date.

We're very happy to announce that we are able to reduce the APC to $1400.

Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
September 5, 2025 at 2:59 AM
Reposted by Csaba Orban
gozziale.bsky.social
This looks pretty cool: ultrasound can now see through the skull! 🧠🔊

The skull has long been a barrier to ultrasound. This reprint shows how to make it quickly transparent → enabling full-depth, high-res fUSI in mice (& humans! 🤯🤯)
Huge congrats to the authors!!!

www.biorxiv.org/content/10.1...
September 3, 2025 at 1:35 PM
Reposted by Csaba Orban
romy-lorenz.bsky.social
What started as a journal club on layer decoding turned into a project thanks to @karolisdegutis.bsky.social. Our preprint challenges a widespread assumption in the field: MVPA is not immune to vascular confounds in laminar GE-BOLD decoding, as shown using a mechanistic laminar response model.
karolisdegutis.bsky.social Karolis Degutis @karolisdegutis.bsky.social · Aug 30
Happy to see this out: our new preprint shows that laminar GE-BOLD fMRI decoding isn’t immune to vascular draining biases. Simulations reveal false positives due to multivariate signal spread across layers, but oversampling + deconvolution can (sometimes) improve specificity.
August 30, 2025 at 2:58 PM
Reposted by Csaba Orban
natureportfolio.nature.com
Longitudinal neuroimaging of participants with planned arm amputations shows that the cortical body map remains stable after amputation. The findings, published in Nature Neuroscience, challenge long-standing theories of brain remapping after limb loss. go.nature.com/4oLSyYO 🧪 #Neuroscience
This image is figure 1 showing the longitudinal investigation of participants with planned arm amputations.
August 25, 2025 at 1:22 PM
Reposted by Csaba Orban
andreashorn.org
🚨 New preprint out! 🚨
“Translating the Transcriptome: A Connectomics Approach for Gene-Network Mapping and Clinical Application”
🔗 doi.org/10.1101/2025... 

🧵 A short thread:
August 22, 2025 at 2:21 PM
Reposted by Csaba Orban
hunterschone.bsky.social
Now out in @natneuro.nature.com

What happens to the brain’s body map when a body-part is removed?

Scanning patients before and up to 5 yrs after arm amputation, we discovered the brain’s body map is strikingly preserved despite amputation

www.nature.com/articles/s41593-025-02037-7

🧵1/18
August 21, 2025 at 9:20 AM
Reposted by Csaba Orban
bttyeo.bsky.social
Great write up of our @nature.com study by @claudia-lopez.bsky.social
August 21, 2025 at 1:22 PM
Reposted by Csaba Orban
drdamienfair.bsky.social
I still get chills

Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts

Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE

see videos, read paper, follow thread
doi.org/10.31234/osf...
August 10, 2025 at 6:23 PM
Reposted by Csaba Orban
rodbraga.bsky.social
🚨 New Preprint 🚨

Targeting intracranial electrical stimulation (ES) to network regions defined within individuals causes network-level effects

By Cyr et al.

***
Q: Can we use individualized network maps from precision fMRI to modulate a targeted network via intracranial ES?

A: Yes!

🧵:
August 5, 2025 at 3:31 PM
Reposted by Csaba Orban
meharpist.bsky.social
Did you know that seeing virtual avatars with coughs or rashes can trigger your brain's immune response? Read more in this fascinating Nature Neuroscience paper @natureportfolio.nature.com 🧪 www.nature.com/articles/s41...
Neural anticipation of virtual infection triggers an immune response - Nature Neuroscience
Serino et al. show that seeing an infectious avatar approach the body in virtual reality triggers an immune response, indicating that the brain prepares the body to fight infections even for perceived...
www.nature.com
July 31, 2025 at 7:03 PM
Reposted by Csaba Orban
micahgallen.com
I’m elated to share our latest publication - out now in @natmentalhealth.nature.com! www.nature.com/articles/s44... - tour de force by @leahbanellis.bsky.social @brainandstomach.bsky.social and the rest of the VMP team!
Stomach–brain coupling indexes a dimensional signature of mental health - Nature Mental Health
Using a relatively large and diverse sample of mostly young adults, this study by Banellis, Rebollo and colleagues examines associations between regional stomach–brain coupling and mental health and i...
www.nature.com
July 30, 2025 at 10:25 AM
Reposted by Csaba Orban
nichols.bsky.social
For me, this work is a classic @ohbmofficial.bsky.social story: In 2023 I wasn't working with @bttyeo.bsky.social but I overheard him at his poster pointing to some accuracy curves saying "I don't why they have this particular shape". That kicked off the collab that led to these results.
bttyeo.bsky.social Thomas Yeo @bttyeo.bsky.social · Jul 17
3/11 Tom's model explains empirical prediction accuracies well across 76 phenotypes from 9 resting-fMRI & task-fMRI datasets (R2 = 0.89), spanning many scanners, acquisitions, racial groups, disorders & ages.

Does this mean that we should collect large datasets with short scans?
July 17, 2025 at 6:34 AM
Reposted by Csaba Orban
shaoshiz.bsky.social
🚨Thrilled to share our latest work just published in @nature.com where we looked into the optimal fMRI scan time for brain-wide association studies (BWAS) 🧠⏱️! Full thread below👇:
bttyeo.bsky.social Thomas Yeo @bttyeo.bsky.social · Jul 17
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social

AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...

doi.org/10.1038/s415...
July 17, 2025 at 2:22 AM
Reposted by Csaba Orban
leonooi.bsky.social
Super thankful to @bttyeo.bsky.social @csabaorban.bsky.social and @shaoshiz.bsky.social for pouring in all the effort to make this work possible!
bttyeo.bsky.social Thomas Yeo @bttyeo.bsky.social · Jul 17
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social

AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...

doi.org/10.1038/s415...
July 17, 2025 at 2:14 AM
Reposted by Csaba Orban
bttyeo.bsky.social
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social

AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...

doi.org/10.1038/s415...
July 17, 2025 at 1:36 AM
Reposted by Csaba Orban
erictopol.bsky.social
—Why did you go to sleep?
—My mitochondria made me do it.
www.nature.com/articles/s41...
Mitochondrial origins of the pressure to sleep - Nature
Research on Drosophila neurons shows links between the need to sleep and aerobic metabolism, indicating that the pressure to sleep may have a mitochondrial origin.
www.nature.com
July 16, 2025 at 10:26 PM
Reposted by Csaba Orban
drdamienfair.bsky.social
Alert!!!!

“An Action Networks Model for Pain”

We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it.

👉 thread below 🧵

osf.io/preprints/ps...
June 26, 2025 at 1:29 PM