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Darío Lupiáñez

@dariloops.bsky.social

980 followers 250 following 47 posts

A bit of 3D gene regulation, single-cell omics and transgenic models. Born and raised in the bay of Algeciras. Enjoying Science and Flamenco at CABD, Seville. Lab website: https://lupianezlab.github.io/Website/ Email: [email protected]

lupianezlab.github.io

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Darío Lupiáñez @dariloops.bsky.social · Jul 17

How bats developed their wings? 🦇

Turns out they reutilize existing gene programs 🔧

Find out more in our paper @natecoevo.nature.com in collaboration with @fany-real.bsky.social and @stemundi.bsky.social labs

www.nature.com/articles/s41...

Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene programme in bat wing development - Nature Ecology & Evolution

Single-cell comparison of developing bat and mouse limbs reveals conservation of cell populations and gene expression patterns, and suggests repurposing of genes involved in proximal limb development ...

www.nature.com

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Reposted by Darío Lupiáñez

SEBD @sebioldev.bsky.social · 2d

We are very pleased to announce our joint meeting with the German @gfeev.bsky.social and the Dutch Developmental Biology Societies, which will take place in Potsdam from the 10-13th of March 2026. Registration is now open! www.uni-potsdam.de/en/gfe-meeti...

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Reposted by Darío Lupiáñez

Denis Duboule @denisduboule.bsky.social · 5d

Vertebrate Genome Evolution. Annual Symposium of the @louisjeantetfdn.bsky.social Foundation in Geneva. Free access on site and on line. Great speakers for a super interesting topic. #SvantePaabo #HenrikKaessmann organisers 🙏 See you there! @biology-unige.bsky.social @genevunige.bsky.social

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Reposted by Darío Lupiáñez

Moreno-Mateos Lab @crisprscan.bsky.social · 8d

Glad to share that the website for the MZT EMBO workshop that I organize together with Ana Boskovic (EMBL, Rome), Antonio Giraldez (Yale U) and Melissa Harrison (U Wisconsin) is out: meetings.embo.org/event/26-awa...
Please spread the word and join us in beautiful Seville next 4-7 May!

Awakening the Genome During Developmental Reprogramming: From Embryos to Organoids

This EMBO Workshop explores the gene-regulatory mechanisms that drive developmental reprogramming upon fertilization. It focuses on the interplay of transcriptional, post-transcriptional, and develop…

meetings.embo.org

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Reposted by Darío Lupiáñez

Manuel Irimia @mirimiam.bsky.social · 16d

Last days to apply! Cool project, cool cities! :-)

(Please repost! 🙏)

Manuel Irimia @mirimiam.bsky.social · Jul 23

🚨🚨🚨

Please RT!

We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets.

Deadline: 30/09/25👇

www.upf.edu

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Darío Lupiáñez @dariloops.bsky.social · 17d

Thanks for being part of the course Ana. We really enjoyed it!

Darío Lupiáñez @dariloops.bsky.social · 18d

Thanks for being part of it!! And thanks to the Conexion Genoma @csic.es for their support!

Darío Lupiáñez @dariloops.bsky.social · 19d

🎁Wrapping up 5 days of science at the National Course of Genetics 🧬 by @segenetica.bsky.social and Conexion Genoma @csic.es

As organizers, @aruizherrera.bsky.social and I have really enjoyed the organization. Thanks to all participants and professors for the lively discussion!!

See you in 2027 😉

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Darío Lupiáñez @dariloops.bsky.social · 19d

🔚Last day of the #CNG2025 by the @segenetica.bsky.social and Conexion Genoma @csic.es

We close our scientific program with talks by @joadelas.bsky.social from UCL on developmental patterning, and Jose Manuel Franco @cnb-csic.bsky.social on transcription factors in plants 🌱

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Darío Lupiáñez @dariloops.bsky.social · 20d

🎉 Adrian de Reus @cbm-csic-uam.bsky.social and Andrea Sempere @cbgpmadrid.bsky.social were the winners of our giveaway 🥳

📖 They received a copy of #SerCientífico, the latest book by @lluismontoliu.bsky.social

🙌 Thanks for the generous donation, Lluis!

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Darío Lupiáñez @dariloops.bsky.social · 20d

🕛 Noon talks by Ana Losada @cniostopcancer.bsky.social on genome organization by cohesin, and @anaconesa.bsky.social @i2sysbio.es on RNA isoform detection and genome annotation🧬

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Darío Lupiáñez @dariloops.bsky.social · 20d

4️⃣ Fourth day of the CNG 2025 by @segenetica.bsky.social and Conexion Genoma.

☀️Morning talks by @mamartirenom.bsky.social @cnag-eu.bsky.social on structural genomics, and @radaiglesiaslab.bsky.social @univcantabria.bsky.social on long-range gene regulation

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Darío Lupiáñez @dariloops.bsky.social · 20d

How digits evolved ✋

Equivalent deletions of Hoxd regulatory domains in 🐟 and 🐭 revealed an ancestral cloacal function, suggesting that distal limb (digit) regulation was co-opted 🤯

👏Kudos @aurhin.bsky.social @chasebolt.bsky.social @homeobox.bsky.social @denisduboule.bsky.social and collab!

Aurelie Hintermann @aurhin.bsky.social · 21d

Are digits modified fins, or evolutionary innovations? Read how we tackled this old question from a new angle🧪
A story with @chasebolt.bsky.social, @homeobox.bsky.social and myself, coordinated by @denisduboule.bsky.social from @college-de-france.fr and published in @nature.com today!
#InHoxWeTrust

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Darío Lupiáñez @dariloops.bsky.social · 21d

And some truffle eggs for dinner 😅

Darío Lupiáñez @dariloops.bsky.social · 21d

And some truffle eggs for dinner 😅

Darío Lupiáñez @dariloops.bsky.social · 21d

🔚 Ending with short presentation from our talented participants on their current projects

Darío Lupiáñez @dariloops.bsky.social · 21d

🔅Noon session with @gonzalezlabbcn.bsky.social from IBB @csic.es on transposable elements, and @aruizherrera.bsky.social from UAB on 3D chromatin organization

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Darío Lupiáñez @dariloops.bsky.social · 21d

🌅 Morning session features talks by Nuria Flames @ibv-csic.bsky.social on the combinatorial action of Transcription Factors, and Mafalda Dias @crg.eu on deep learning approaches to study human variation

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Darío Lupiáñez @dariloops.bsky.social · 21d

🥉Third day of #CNG2025 by @segenetica.bsky.social and Conexion Genoma @csic.es

A pleasure to organize this with the great @aruizherrera.bsky.social

Besides great science🔬, we are enjoying sunny weather ☀️ at the mountains of Madrid 🏔️ (some participants even tried the swimming pool at the lodge)

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Darío Lupiáñez @dariloops.bsky.social · 22d

🕛 The afternoon session goes on with @romangp.bsky.social @cabimer.bsky.social on proteomic approaches, and @bombarelya.bsky.social @ibmcp.bsky.social on genome assembly and annotation ✏️

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Darío Lupiáñez @dariloops.bsky.social · 22d

✌️2nd day of the National Genetics Course by @segenetica.bsky.social and Conexion Genoma🧬

☀️Morning session with @marcguellc.bsky.social @upf.edu on genome engineering and synthetic evolution, and @miguel-torres-1963.bsky.social from CNIC on transgenic animal models.

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Darío Lupiáñez @dariloops.bsky.social · 23d

We continue this afternoon with talks by @maitehuartelab.bsky.social from CIMA_univ on lncRNAs and by @obog.bsky.social @cabd-upo-csic.bsky.social on DNA methylation 🤓

Darío Lupiáñez @dariloops.bsky.social · 23d

This morning, talks by @sblancolab.bsky.social @ciccancer.bsky.social on the epitranscriptome in cancer and @tmarquesbonet.bsky.social @ibe-barcelona.bsky.social on primate genomics

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Darío Lupiáñez @dariloops.bsky.social · 23d

⚽Kick-of of the X National Course of Genetics organized by the @segenetica.bsky.social & Conexion Genoma @csic.es with @aruizherrera.bsky.social and myself as coordinators.

One week discovering strategies to read, interpret and edit genomes 🧬

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