What role does myelination play in the development of parvalbumin-positive (PV) interneurons in the prefrontal cortex? This study shows that juvenile demyelination disrupts PV interneuron firing and s...

Reliable measuring the voltage dynamics of individual neurons in the intact brain is significantly challenging. Here authors developed an all-optical method combining two-photon voltage imaging and optogenetics to measure and induce synaptic plasticity in vivo, revealing LTP of inhibition in cerebellar circuits and providing a blueprint to link synaptic changes to learning.

Neuronal firing patterns are the consequence of precise variations in neuronal membrane potential, which are themselves shaped by multiple ionic cu...

Jupyter notebook templates for processing and analyzing neuroscience data. - dav1dcg/neuro-notebook-templates

Abstract figure legend Summary of the study where simulated recordings (left) were used to characterise the effect of incomplete detection on mini (mPSC) analysis. Recording noise levels (red) determ...

Over the past decade and a half, a new understanding has emerged of the role of vision during the critical period in the primary visual cortex. Rather than driving competition for cortical space, visi...

Neural activity in awake organisms shows widespread and spatiotemporally diverse correlations with behavioral and physiological measurements. We propose that this covariation reflects in part the dyna...

Information transfer in mammalian cerebral cortex is dependent on GABAergic interneuron circuits that are widely assumed to be uniform across the neoc…

Garcia et al. present RESPAN, a pipeline that enables automated dendritic spine analysis through seamless integration of deep learning image restoration and segmentation capabilities with comprehensiv...

— Last updated on September 8, 2024 — The mouse (Mus musculus) is currently the most commonly used animal model in neuroscience research, followed by rats (post), zebrafish (post), Drosophila (post…

The use of complementary, alternative and integrative medicine (CAIM) is highly prevalent among autistic individuals. This umbrella review finds that there is no high-quality evidence to support the e...

The International Brain Laboratory presents a brain-wide electrophysiological map obtained from pooling data from 12 laboratories that performed the same standardized perceptual decision-making task i...

Synaptic transmission has long been thought to regulate neuronal wiring during postnatal development, but this assumption remains largely untested....

Transcranial electrical stimulation (tES) encompasses non-invasive neuromodulation techniques, such as transcranial direct and alternating current stimulation, which modulate the central nervous syste...

Noninvasive brain stimulation (NIBS) methods can modulate brain plasticity, the fundamental process by which synaptic connections are strengthened or weakened in response to synaptic activity or exter...