davidjlynn.bsky.social
David Lynn
@davidjlynn.bsky.social
70 followers 97 following 7 posts
Professor and Group Leader at SAHMRI and Flinders University. Scientific Director SA Genomics Centre. Research interests in systems immunology; host-microbe interactions; genomics, cancer systems biology.
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davidjlynn.bsky.social
David Lynn @davidjlynn.bsky.social · 27d
I'm looking forward to speaking at this exciting conference next year. If you're interested in the latest in microbiome research please check it out.
eventswcs.bsky.social
Wellcome Connecting Science Learning and Training @eventswcs.bsky.social · 29d
Bursaries to support your participation at our Microbiome research conference! #Microbiome26

Get up to 50% off the conference registration fee - apply by 24 November 📩

Join us to explore the latest tools and approaches driving advances in the field.

📎bit.ly/4kttBOX
#MicrobiomeSky #AcademicSky
Wellcome Connecting Science hybrid conference Microbiome Interactions in Health and Disease Conference dates: 2-4 March 2026 Location: Hinxton Hall Conference Centre, Wellcome Genome Campus, UK and online Bursary and abstract deadline: 24 November 2025 Registration deadline In person: 2 February Virtual: 14 February
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davidjlynn.bsky.social
David Lynn @davidjlynn.bsky.social · Apr 28
www.the-scientist.com/early-life-a...
Early Life Antibiotics Put Vaccine Response at Risk
While antibiotics given in the first week of life reduce vaccine responses at 15 months, probiotics might counteract these effects.
www.the-scientist.com
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davidjlynn.bsky.social
David Lynn @davidjlynn.bsky.social · Apr 25
Thanks @natrevimmunol.bsky.social for highlighting our recent @nature.com paper! @flindersuniversity.bsky.social @sahmri.bsky.social
natrevimmunol.nature.com
Nature Reviews Immunology @natrevimmunol.nature.com · Apr 23
NEW Highlight of @nature.com paper by @davidjlynn.bsky.social and colleagues @sahmri.bsky.social reporting a prospective observational study of human immune responses to #vaccination after early-life #antibiotic exposure.
#immunology #immunosky #medsky #IDsky #pedsky #publichealth
Neonatal antibiotics impair infant vaccine responses - Nature Reviews Immunology
A prospective observational study of human immune responses to vaccination after early-life antibiotic exposure shows that neonatal exposure reduces the immune response to several vaccine antigens and...
www.nature.com
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davidjlynn.bsky.social
David Lynn @davidjlynn.bsky.social · Apr 2
Based on these findings we will soon start a randomised controlled trial to determine if a probiotic intervention can boost vaccine responses in infants that received antibiotics in the neonatal period. Funded by
@WCHFoundation
davidjlynn.bsky.social
David Lynn @davidjlynn.bsky.social · Apr 2
Very grateful to all our collaborators especially @HelenSMarshall and her team, the infants and their parents who participated in our study, our facilities incl @SA_genomics and the @sahmri.bsky.social
germ-free and flow facilities and our funders @nhmrc.bsky.social and the WCH Foundation
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davidjlynn.bsky.social
David Lynn @davidjlynn.bsky.social · Apr 2
Neonates who received antibiotics had significantly lower antibody titres to multiple different vaccine antigens especially polysaccharides in the PCV13 vaccine.
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davidjlynn.bsky.social
David Lynn @davidjlynn.bsky.social · Apr 2
Our paper out today in @nature.com shows the important role Bifidobacteria in the infant gut microbiota play in mediating optimal responses to vaccination.
nature.com.web.brid.gy
Nature @nature.com.web.brid.gy · Apr 2
Bifidobacteria support optimal infant vaccine responses
Nature, Published online: 02 April 2025; doi:10.1038/s41586-025-08796-4 Neonatal antibiotic use is shown to reduce immune response to infant vaccines, accompanied by reduced abundance of Bifidobacteria in the gut microbiota, with experiments in mice indicating that probiotic therapy could be beneficial.
www.nature.com
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