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Laboratory of Exercise and Health - ETH Zürich @debocklab.bsky.social · 7d

1/10/2015-1/10/2025 🎂
10 years @ethz.ch #timeflies
10 years of great people and exciting science
thanks to all people who were part of the lab, who collaborated with us, and who made those years a fantastic time!

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Laboratory of Exercise and Health - ETH Zürich @debocklab.bsky.social · 7d

Good luck Emm! Sad to see you leaving us but hope to stay in touch. Enjoy Basel!

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Laboratory of Exercise and Health - ETH Zürich @debocklab.bsky.social · 10d

Unfortunately similar experience for me. I left X but Bluesky currently less than 10% of visibility…

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Laboratory of Exercise and Health - ETH Zürich @debocklab.bsky.social · 24d

Data can be freely explored at shiny.debocklab.hest.ethz.ch/Turiel-et-al/

Human PAD Portal

shiny.debocklab.hest.ethz.ch

Laboratory of Exercise and Health - ETH Zürich @debocklab.bsky.social · 24d

Great and unique resource for those who are interested in studying peripheral artery disease mechanisms 👇. Congratulations to Guillermo Turiel and huge thanks to all our collaborators @ethz.ch and Kantonsspital Baden. #PAD #endothelialcells #peripheralarterydisease
rdcu.be/eGpZI

Single-cell compendium of muscle microenvironment in peripheral artery disease reveals altered endothelial diversity and LYVE1+ macrophage activation

Nature Cardiovascular Research - Using single-cell and spatial transcriptomics on muscle samples from non-ischemic patients and patients with peripheral artery disease (PAD), Turiel et al. identify...

rdcu.be

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Laboratory of Exercise and Health - ETH Zürich @debocklab.bsky.social · 29d

On my way to #BeNeVBO, taking the train to Leuven as I have done for many years!

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Reposted by Laboratory of Exercise and Health - ETH Zürich

Ondine Cleaver @ondinecleaver.bsky.social · Aug 1

As scientists, we all need to speak up. Thanks, Guillermo Oliver and @labonnelab.bsky.social for all the science advocacy. 🔬

But we ALL need to be telling our friends, family, and neighbors how important science is. Educate them about the medical cures that came from basic discoveries.

#science

Society for Developmental Biology @socdevbio.bsky.social · Jul 31

Developmental biologist and former SDB board member Guillermo Oliver published a letter in Science 'US funding freeze threatens biomedical research' in which he highlights the effects of the federal funding freeze on Northwestern University & other institutions. www.science.org/doi/full/10....

Letters
US funding freeze threatens biomedical research
Guillermo Oliver, Northwestern University

Federal funding is crucial for producing cutting-edge scientific, technological, and clinical breakthroughs, allowing universities to cover salaries, purchase reagents and equipment, and enroll patients in clinical trials. Yet in April, funding freezes were enacted at that affect Harvard University, Columbia University, Princeton University, Brown University, University of Pennsylvania, and Northwestern University (1). At Northwestern, almost $800 million has been frozen, without official notification, updates, or recourse (2,3). University faculty and leadership must speak out to make the public and colleagues aware of the funding freeze and to emphasize the dire effects of this policy on research, patients, and public health (4).

The frozen funding corresponds to grants that have already been awarded after a stringent, competitive evaluation process that deemed them valuable. To earn a federal grant, basic and clinical researchers must generate and test their results in a laboratory or enroll patients in a long-term clinical trial. Next they must prepare a grant application and submit it to a government funding agency, where a panel of experts carefully reviews it. Only a small number of applications are funded, and it can take up to a year to receive the money.

Professors, postdocs, student, and laboratory technicians at US universities come from all over the world to contribute to research projects that could improve human health. Funding freezes with unspecified end dates are demoralizing and stressful, potentially depleting the current and future clinical workforce. Students and postdocs are questioning the viability of a scientific career (5,6), and job applications from domestic and international scientists are likely to decline.

These unprecedented, punitive measures against universities and medical schools put both research and patient welfare at risk.

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Laboratory of Exercise and Health - ETH Zürich @debocklab.bsky.social · Aug 1

Returning home from a fantastic gordon Research Confernce in #angiogenesis. Thanks @karinayaniv.bsky.social and @anne eichmann for the splendid organization! Couldn’t leaave the USA without a big hug to Gillian and Jing ❤️.

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Reposted by Laboratory of Exercise and Health - ETH Zürich

Daniel Drucker @danieljdrucker.bsky.social · Apr 28

The emerging vascular biology of GLP-1 medicines in people with #T2D and PAD dom-pubs.onlinelibrary.wiley.com/doi/full/10....

Liraglutide improves peripheral perfusion and markers of angiogenesis and inflammation in people with type 2 diabetes and peripheral artery disease: An 18‐month follow‐up of a randomized clinical trial

Aims In a six-month randomized clinical trial, improved peripheral perfusion has been shown with liraglutide, associated with favourable vascular effects in people with type 2 diabetes and periphera...

dom-pubs.onlinelibrary.wiley.com

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Laboratory of Exercise and Health - ETH Zürich @debocklab.bsky.social · Apr 28

Excited to be part of the first #Hi-TAC symposium in beautiful Heidelberg. Team efforts in angiocardioscience will make the difference!

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Reposted by Laboratory of Exercise and Health - ETH Zürich

Mariona Graupera @grauperalab.bsky.social · Feb 26

We are excited to share our work on Context-dependent response of endothelial cells to PIK3CA mutation. A tour the force of many; thank you all for your invaluable contribution. @aangulou.bsky.social @ruibenedito.bsky.social @debocklab.bsky.social @sandradcastillo.bsky.social
bit.ly/4blKSqa

Context-dependent response of endothelial cells to PIK3CA mutation

Cancer mutations in the PIK3CA gene cause congenital disorders. The endothelium is among the most frequently affected tissues in these disorders, displaying aberrant vascular overgrowth in the form of...

bit.ly

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Laboratory of Exercise and Health - ETH Zürich @debocklab.bsky.social · Feb 14

When you're working in an engineering school you end up talking about mechanics ;-). Together with Jess Snedeker-lab, we embarked on studying the molecular mechanisms underlying #tendinopathy. Currently revising the comments of the reviewers, but you can read it now:
www.biorxiv.org/content/10.1...

HIF1α gates tendon response to overload and drives tendinopathy independently of vascular recruitment

Tendons are mostly avascular dense connective tissues that link muscles to bones, withstanding some of the highest mechanical stresses in the body. Mechanical overload and tissue hypervascularity are ...

www.biorxiv.org

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Reposted by Laboratory of Exercise and Health - ETH Zürich

Thibaux Van der Stede @thibauxvanderstede.bsky.social · Feb 7

Cellular crosstalk in skeletal muscle? A surprising role for mast cells? Histamine as a signal transducer during exercise? Check out the story in @cp-cellmetabolism.bsky.social 🧵

@wimderave.bsky.social, @ugent-fge.bsky.social, @fwovlaanderen.bsky.social

www.sciencedirect.com/science/arti...

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Reposted by Laboratory of Exercise and Health - ETH Zürich

EVBO @evborg.bsky.social · Feb 6

#EVBOSummerSchool 2025: Please help spread the news!
10-11 June 2025 | Biomedicum Helsinki, Finland
Registration will open soon. Stay tuned!
The summer school will be preceded by the excellent and free-of-charge Wihuri Research Symposium on Cardiovascular Biology!

More info https://buff.ly/42I9fvY

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Laboratory of Exercise and Health - ETH Zürich @debocklab.bsky.social · Feb 6

Proud about this one! Together with EA Richter ending up twice in the same issue of @cp-cellmetabolism.bsky.social ! #luck or my lab is great ;-). Thanks @wimderave.bsky.social and Zelzer labs for the nice collaborations!
authors.elsevier.com/sd/article/S...
authors.elsevier.com/c/1kZR45WXUl...

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Laboratory of Exercise and Health - ETH Zürich @debocklab.bsky.social · Jan 7

Accepted only few days before the end of 2024, happy to share it at the start of 2025. Hoping for a happy, healthy and peaceful year for ALL!! #skeletalmuscle #FAPs #osteoarthritis and #worldpeace

rdcu.be/d5vnJ

Intramuscular fatty infiltration and its correlation with muscle composition and function in hip osteoarthritis | Skeletal Muscle

rdcu.be

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Laboratory of Exercise and Health - ETH Zürich @debocklab.bsky.social · Dec 17

We are recruiting a professor for integrative human physiology or pathophysiology! Topics ranging from exercise physiology to endocrinology and metabolism and beyond. Please share this amongst your network or apply ;-).
ethz.ch/en/the-eth-z...

Professor of Human Integrative (Patho)physiology

ethz.ch

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Laboratory of Exercise and Health - ETH Zürich @debocklab.bsky.social · Dec 16

#lifeofthescientist #sla #eth_eng getting ready for the annual Christmas karaoke!

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Laboratory of Exercise and Health - ETH Zürich @debocklab.bsky.social · Dec 7

Thanks Ulf Eriksson for the great two days in #KarolinskaInstitutet. First being the opponent of your last PhD student (my first time!), and today joining you to the #nobellectures2024 #microRNA

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