Deen Sun
@deensun3.bsky.social
Incoming assistant professor at Peking U | Postdoc in Kai Johnsson Lab at MPIMR Heidelberg | Ph.D in Xing Chen Lab at Peking U | Chemical biology, Expansion🔬, Molecular probes
scholar.google.co.kr/citations?user…
scholar.google.co.kr/citations?user…
🚨Excited to share this collaborative work with Ming-Ming. 🎉Check it out!▶️https://www.biorxiv.org/content/10.64898/2025.12.05.692539v1
New paper out!
We developed localizable chemigenetic fluorescent sensors for key metal ions (K⁺, Na⁺, Ca²⁺, Mg²⁺, Zn²⁺, etc.). Our K⁺ indicators work beautifully in live cells and neurons. Samples available on request.
Huge thanks to @deensun3.bsky.social and Kai @mpi-mr.bsky.social.
Link 👇
We developed localizable chemigenetic fluorescent sensors for key metal ions (K⁺, Na⁺, Ca²⁺, Mg²⁺, Zn²⁺, etc.). Our K⁺ indicators work beautifully in live cells and neurons. Samples available on request.
Huge thanks to @deensun3.bsky.social and Kai @mpi-mr.bsky.social.
Link 👇
Localizable fluorescent metal ion indicators with tunable colors
Elucidating the role of metal ion homeostasis in physiological and pathological processes requires detection tools with high sensitivity and selectivity, spectral versatility, and precise subcellular ...
www.biorxiv.org
December 8, 2025 at 10:01 PM
🚨Excited to share this collaborative work with Ming-Ming. 🎉Check it out!▶️https://www.biorxiv.org/content/10.64898/2025.12.05.692539v1
Reposted by Deen Sun
🎉🌟Big news! Our Director @kjohnsson.bsky.social has received an @erc.europa.eu Synergy Grant, together with teams from EPFL @sulianamanley.bsky.social and @unibe.ch! 👏They’ll explore how mitochondria communicate with other cell parts🔬 #ERCSyG #maxplanck #mpimr #science
www.mr.mpg.de/14662972/erc...
www.mr.mpg.de/14662972/erc...
ERC Synergy Grant for MPI Director Kai Johnsson
www.mr.mpg.de
November 6, 2025 at 11:41 AM
🎉🌟Big news! Our Director @kjohnsson.bsky.social has received an @erc.europa.eu Synergy Grant, together with teams from EPFL @sulianamanley.bsky.social and @unibe.ch! 👏They’ll explore how mitochondria communicate with other cell parts🔬 #ERCSyG #maxplanck #mpimr #science
www.mr.mpg.de/14662972/erc...
www.mr.mpg.de/14662972/erc...
Reposted by Deen Sun
😎 Back from our #scientificretreat 2025 in Neckarsulm, full of scientific exchange and #teamspirit! 🤩🌟One highlight was the tour of the Bildungscampus in Heilbronn, where two new departments of our institute will be established, and the Innovation Park for #AI #IPAI 🚀
#maxplanck #mpimr #letsmingle
#maxplanck #mpimr #letsmingle
September 18, 2025 at 1:54 PM
😎 Back from our #scientificretreat 2025 in Neckarsulm, full of scientific exchange and #teamspirit! 🤩🌟One highlight was the tour of the Bildungscampus in Heilbronn, where two new departments of our institute will be established, and the Innovation Park for #AI #IPAI 🚀
#maxplanck #mpimr #letsmingle
#maxplanck #mpimr #letsmingle
Reposted by Deen Sun
Recently I learnt that EMBL-EBI has a free online course about AlphaFold — how it works, strengths and limitations, how to use it — and it's very good!
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
AlphaFold - A practical guide
AlphaFold - A practical guide
www.ebi.ac.uk
July 21, 2025 at 3:33 PM
Recently I learnt that EMBL-EBI has a free online course about AlphaFold — how it works, strengths and limitations, how to use it — and it's very good!
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
Reposted by Deen Sun
#glycotime Legionella effector LtpM is found to recognize strict two-residue sequons for site-specific O-glucosylation with minimal perturbations to a target protein and is used to show that O-glucose can act as a constitutively active O-GlcNAc mimic
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Protein β-O-glucosylation by Legionella LtpM through short consensus sequons G-T/S and S-G - Nature Chemical Biology
Legionella effector LtpM is found to recognize short two-residue sequons, enabling site-specific O-glucosylation with minimal perturbations to a target protein, and is used to show that O-glucose can ...
www.nature.com
July 15, 2025 at 6:32 PM
#glycotime Legionella effector LtpM is found to recognize strict two-residue sequons for site-specific O-glucosylation with minimal perturbations to a target protein and is used to show that O-glucose can act as a constitutively active O-GlcNAc mimic
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Deen Sun
Finally out in Nature Chem Bio:
SNAP-tag2 for faster and brighter protein labeling
www.nature.com/articles/s41...
Thank you Steffi and Veselin.
SNAP-tag2 for faster and brighter protein labeling
www.nature.com/articles/s41...
Thank you Steffi and Veselin.
SNAP-tag2 for faster and brighter protein labeling - Nature Chemical Biology
SNAP-tag is a widespread tool for labeling protein for bioimaging. Now, Kühn et al. report SNAP-tag2 with increased labeling kinetics and brightness, which translates into a better performance in live...
www.nature.com
July 3, 2025 at 7:45 PM
Finally out in Nature Chem Bio:
SNAP-tag2 for faster and brighter protein labeling
www.nature.com/articles/s41...
Thank you Steffi and Veselin.
SNAP-tag2 for faster and brighter protein labeling
www.nature.com/articles/s41...
Thank you Steffi and Veselin.
Reposted by Deen Sun
Teaching an old bacterial protein new tricks: Fast, bright and reversible rhodamine tags for live-cell imaging:
www.biorxiv.org/content/10.1...
Congratulations to Julian Kompa and the entire team.
www.biorxiv.org/content/10.1...
Congratulations to Julian Kompa and the entire team.
Fast, Bright and Reversible Rhodamine Tags for Live-Cell Imaging
We present Rho-tag and SiR-tag, engineered protein tags derived from bacterial multidrug-resistance proteins that bind unsubstituted (silicon-) rhodamines with nanomolar affinity, enabling fast, rever...
www.biorxiv.org
July 9, 2025 at 7:58 PM
Teaching an old bacterial protein new tricks: Fast, bright and reversible rhodamine tags for live-cell imaging:
www.biorxiv.org/content/10.1...
Congratulations to Julian Kompa and the entire team.
www.biorxiv.org/content/10.1...
Congratulations to Julian Kompa and the entire team.
Reposted by Deen Sun
Molecular recording of cellular protein kinase activity with chemical labeling:
www.nature.com/articles/s41...
Congratulations to De-en Sun and the entire team.
www.nature.com/articles/s41...
Congratulations to De-en Sun and the entire team.
Molecular recording of cellular protein kinase activity with chemical labeling - Nature Chemical Biology
Molecular recorders based on kinase activity-dependent protein labeling track specific kinase activities to understand their link to cellular phenotypes in heterogeneous cell populations and in vivo.
www.nature.com
July 10, 2025 at 5:46 PM
Molecular recording of cellular protein kinase activity with chemical labeling:
www.nature.com/articles/s41...
Congratulations to De-en Sun and the entire team.
www.nature.com/articles/s41...
Congratulations to De-en Sun and the entire team.