Dutch Society for Mass Spectrometry
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denvms.bsky.social
Dutch Society for Mass Spectrometry
@denvms.bsky.social
The Dutch Society for Mass Spectrometry (NVMS) aims to connect scientists from various fields of mass spectrometry and foster interactions among members from academia and industry, bridging the gap between young and experienced mass spectrometrists.
Reposted by Dutch Society for Mass Spectrometry
From Identification to Insight: Making Full Use of the Diagnostic Potential of MS/MS Proteotyping in Clinical Microbiology Using Efficient Bioinformatics pubs.acs.org/doi/10....

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#proteomics #prot-paper
October 29, 2025 at 4:20 PM
Reposted by Dutch Society for Mass Spectrometry
For those who perform thermal proteome profiling (TPP) experiments, you might find this new data analysis approach (and open source Python software) useful. Developed by postdoc @jfhevler.bsky.social 🙏

arxiv.org/abs/2508.096...
Thermal Tracks: A Gaussian process-based framework for universal melting curve analysis enabling unconstrained hit identification in thermal proteome profiling experiments
Thermal Tracks is a Python-based statistical framework for analyzing protein thermal stability data that overcomes key limitations of existing thermal proteome profiling (TPP) work-flows. Unlike stand...
arxiv.org
October 24, 2025 at 10:18 PM
We are excited to share the final program for the NVMS Fall Meeting on November 19, 2025, at the House of Connections in Groningen. Download the program here: www.nvms.nl/index.php/nv...

See you all there! 😀🧪✨

#NVMS #MassSpec #RUG #Science
NVMS Fall Meeting 2025 – Program Announced! - NVMS
We are pleased to share the full program for the upcoming NVMS Fall Meeting, taking place on Wednesday, November 19, 2025, at the House of Connections in Groningen.
www.nvms.nl
October 30, 2025 at 3:46 PM
Reposted by Dutch Society for Mass Spectrometry
Hey #TeamMassSpec,

Many non-human proteomics studies still search against taxon-filtered FASTAs.

❌ Redundant sequences
❌ Inflated search space
✅ Reference proteomes cut redundancy, improve annotation, and make results comparable.

👉 Time to move beyond taxon filters. #proteomics #massspec #uniprot
September 30, 2025 at 2:21 PM
Reposted by Dutch Society for Mass Spectrometry
Breaking barriers in the sensitive and accurate mass determination of large DNA plasmids by mass photometry: Molecular Therapy Nucleic Acids www.cell.com/molecular-th.... Even visualizing > 10 million Da plasmids by the incredible Eduard Ebberink
Breaking barriers in the sensitive and accurate mass determination of large DNA plasmids by mass photometry
Heck and colleagues developed a mass photometry-based method for accurate and fast mass determination of plasmid DNA. Conventional mass photometry methods are not applicable for large DNA particles; h...
www.cell.com
September 19, 2025 at 10:21 AM
Reposted by Dutch Society for Mass Spectrometry
Excited to share Modanovo, our transformer-based method for de novo peptide sequencing, which supports a broad range of post-translational modifications (PTMs)!
www.biorxiv.org/content/10.1...
#proteomics #massspectrometry #PTM
Modanovo: A Unified Model for Post-Translational Modification-Aware de Novo Sequencing Using Experimental Spectra from In Vivo and Synthetic Peptides
Post-translational modifications (PTMs) play a central role in cellular regulation and are implicated in numerous diseases. Database searching remains the standard for identifying modified peptides fr...
www.biorxiv.org
September 18, 2025 at 7:59 AM
Reposted by Dutch Society for Mass Spectrometry
Molecular Characterization of Natural Organic Matter Using Complementary Liquid Chromatography–Mass Spectrometry and Gas Chromatography–Mass Spectrometry Techniques #JChromA www.sciencedirect.com/science/arti...
Molecular Characterization of Natural Organic Matter Using Complementary Liquid Chromatography–Mass Spectrometry and Gas Chromatography–Mass Spectrometry Techniques
Given the impact of natural organic matter (NOM) on water quality and treatment, understanding its properties is essential in water chemistry. However…
www.sciencedirect.com
September 30, 2025 at 5:59 PM
Reposted by Dutch Society for Mass Spectrometry
What does a language model know about proteins? www.nature.com/artic...

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#proteomics #prot-paper
September 30, 2025 at 6:40 PM
Great news! 🎉 The abstract deadline is extended to Oct 7, 2025! Don’t miss your chance to share your work 🚀 #NVMS #MassSpec
Join us for the NVMS Fall Meeting 2025 with the Dutch Mass Spec community!!!🧪✨😀

📅 19 November 2025
📍 House of Connections, Groningen

🎤 Present your research! Submit an abstract for a poster or oral presentation: www.nvms.nl/index.php/re...

Your NVMS Board

#NVMS2025 #MassSpec
www.nvms.nl
September 30, 2025 at 10:07 PM
Join us for the NVMS Fall Meeting 2025 with the Dutch Mass Spec community!!!🧪✨😀

📅 19 November 2025
📍 House of Connections, Groningen

🎤 Present your research! Submit an abstract for a poster or oral presentation: www.nvms.nl/index.php/re...

Your NVMS Board

#NVMS2025 #MassSpec
www.nvms.nl
September 8, 2025 at 9:43 AM
Reposted by Dutch Society for Mass Spectrometry
🕷️Spiders in your blood? Don’t worry, these are protein molecules of C4BP protein, part of your immune system. Just like real spiders, they grab prey with their “legs.” Watch them in action! Intrigued, check the paper of @tkadava.bsky.social doi.org/10.1016/j.mc... @bijvoet-centre.bsky.social
September 4, 2025 at 2:27 PM
Reposted by Dutch Society for Mass Spectrometry
New paper online:

Ångström-resolution imaging of cell-surface glycans.

The molecular organization of sugars in the native #glycocalyx has been resolved at 9 ångström using bioorthogonal metabolic labeling and #superresolution imaging of DNA barcodes.

#Glycotime

www.nature.com/articles/s41...
Ångström-resolution imaging of cell-surface glycans - Nature Nanotechnology
By combining bioorthogonal metabolic labelling and resolution enhancement through sequential imaging of DNA barcodes, the molecular organization of individual sugars in the native glycocalyx has been ...
www.nature.com
July 28, 2025 at 9:44 AM
Reposted by Dutch Society for Mass Spectrometry
Boosting Orbitrap MS/MS speed to ∼70 Hz? 🚀

Read how we did it in our latest paper 👇

pubs.acs.org/doi/10.1021/...
Enhancing Tandem MS Sensitivity and Peptide Identification via Ion Preaccumulation in an Orbitrap Mass Spectrometer
High-throughput mass spectrometry-based proteomics has gained increasing interest for both academic and industrial applications. As implementation of faster gradients has facilitated higher sample thr...
pubs.acs.org
July 1, 2025 at 12:29 PM
Reposted by Dutch Society for Mass Spectrometry
We’re excited to announce the publication of Cascadia, our new de novo sequencing model designed for DIA data. By extending the transformer architecture to fully capture the complexities of DIA data, we achieve state-of-the-art performance.

www.nature.com/articles/s41...
A transformer model for de novo sequencing of data-independent acquisition mass spectrometry data - Nature Methods
Cascadia is a mass spectrometry-based de novo sequencing model that uses a transformer architecture to handle data-independent acquisition data and achieves substantially improved performance across a...
www.nature.com
July 3, 2025 at 1:34 AM
Reposted by Dutch Society for Mass Spectrometry
Are you looking forward to attending #EuPA2025 in beautiful Saint-Malo? Get ready for an enriching experience in extraordinary #proteomics!

🗓️ Mark your calendar for the SCIEX lunch symposium, taking place on Wednesday, June 18!

🔗 Full show agenda 👉 bit.ly/3HcA6Hw

#SkepticsWelcome #ZenoTOF8600
June 16, 2025 at 8:54 PM
Reposted by Dutch Society for Mass Spectrometry
Free structural MS hands-on workshop @ BIOCEV (CZ)

📅 Sept 15–19, 2025

For PhDs, postdocs & undergrads (CZ/SK)

HDX-MS, native MS, cross-linking, high-res MS, data processing

Apply by July 31 → bit.ly/3HNyzIg

@spidocs.bsky.social @mbuavcr.bsky.social @ciisbinstructcz.bsky.social
June 25, 2025 at 9:14 AM
🌞Wishing everyone in the mass spec community a fantastic summer break!

Whether you are kicking back with the NVMS summer newsletter 👉 www.nvms.nl/index.php/nv... or diving into fresh data, wishing you sunshine, fun, and great results! 😄

#MassSpec #NVMS
July 17, 2025 at 2:48 PM
Reposted by Dutch Society for Mass Spectrometry
We explored the Excedion Pro Mass Analyzer with faster & more efficient EThcD capabilities, launched @asms.org, to more efficiently convert MS2 spectra to PSMs, as quality & unambiguous identification are more important parameters than peptide numbers. www.biorxiv.org/content/10.1...
Increased EThcD efficiency on the hybrid Orbitrap Excedion Pro Mass Analyzer extends the depth in identification and sequence coverage of HLA class I immunopeptidomes
Gaining a complete and unbiased understanding of the non-tryptic peptide repertoire presented by HLA-I complexes by LC-MS/MS is indispensable for therapy design for cancer, autoimmunity and infectious...
www.biorxiv.org
June 2, 2025 at 6:04 AM
Reposted by Dutch Society for Mass Spectrometry
Couldn’t find and forgot to tag @lperezpaneda.bsky.social on this, she did awesome work analyzing the data!
These new archaeal proteases are great for de novo antibody sequencing by mass spec. Great work by @tshamorkina.bsky.social , Laura and @tkadava.bsky.social together with @hecklab.bsky.social.

www.biorxiv.org/content/10.1...
June 2, 2025 at 7:55 AM
Reposted by Dutch Society for Mass Spectrometry
📢Conference alert📢

Only one week left to register for the Engineering Life 2025 Symposium at Dresden September 1-3. This year's edition focuses on the function of mechanical forces in biology.

engineering-life-dresden.de
Engineering Life 2025: ORIGIN AND FUNCTION OF MECHANICAL FORCES IN BIOLOGY
Engineering Life 2025, biological forces, force spectroscopy, measuring forces, developmental forces, molecular motors, forces in morphogenesis, cytoskeleton, DNA mechanics, bionanotechnology
engineering-life-dresden.de
June 22, 2025 at 9:12 AM
Reposted by Dutch Society for Mass Spectrometry
Assessment of false discovery rate control in tandem mass spectrometry analysis using entrapment www.nature.com/artic...

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#proteomics #prot-paper
June 22, 2025 at 12:40 PM
Reposted by Dutch Society for Mass Spectrometry
NVMS Spring Meeting 2025 - 1/3 📢
What a fantastic NVMS Spring Meeting at Sanquin Research in Amsterdam! The day was packed with cutting-edge mass spec talks, and a great atmosphere for networking. A big thank you to all speakers, attendees, and sponsors who made it such a success! 👍👏
www.nvms.nl
NVMS
Nederlandse Vereniging voor Massaspectrometrie
www.nvms.nl
May 31, 2025 at 12:21 AM