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derekkaknes.bsky.social
@derekkaknes.bsky.social
Reposted
SURMOUNT-5 Among participants with #obesity but without diabetes, treatment with tirzepatide was superior to treatment with semaglutide with respect to reduction in body weight and waist circumference at week 72 www.nejm.org/doi/full/10....
Tirzepatide as Compared with Semaglutide for the Treatment of Obesity | NEJM
Tirzepatide and semaglutide are highly effective medications for obesity management. The efficacy and safety of tirzepatide as compared with semaglutide in adults with obesity but without type 2 di...
www.nejm.org
May 11, 2025 at 10:39 PM
Somebody explain to me why the NBA needs to play an 82 game season and then have this Grizzlies team get beat by 50. Rule should be that only teams that finish within ten games of the conference leader get a chance at the playoffs.
April 20, 2025 at 6:56 PM
Reposted
More preclinical data highlighting that biased agonism is a strong predictor of in vivo efficacy for GLP-1R agonists independent of factors like intrinsic cAMP potency or pharmacokinetics #weightloss www.sciencedirect.com/science/arti...
March 27, 2025 at 8:33 PM
The SGLT2i class might be the most egregious example of this. Bexagliflozin is available for $47 on CostPlusDrugs, yet the two drugs with 95% market share retail for $500.
February 17, 2025 at 8:49 PM
@mikeduncan.bsky.social loving your series on the Martian Revolution, but I keep getting confused on the dates. When do the revolutionaries introduce the revolutionary calendar and start marking dates by Martian solar years instead of earth years? Or are you skipping that part for sanity’s sake?
February 11, 2025 at 11:39 AM