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André Dias

@dias-andre.bsky.social

150 followers 220 following 7 posts

Developmental biologist @AMAlab @upf. Playing with cells & genes to understand the role of signalling during mammalian gastrulation. PhD @IGCiencia

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André Dias @dias-andre.bsky.social · Jan 13

www.biorxiv.org/content/10.1...

Here we explore the role of #Wnt and #Nodal signalling during mammalian gastrulation using #gastruloids. Building on the work of many labs, we propose that antagonistic signalling-dependent #modularity in the PS establishes the early mammalian body plan.

A temporal coordination between Nodal and Wnt signalling governs the emergence of the mammalian body plan

Nodal and Wnt signalling play an important role in the emergence of the mammalian body plan, primarily by orchestrating gastrulation and primitive streak formation. While the literature suggests that ...

www.biorxiv.org

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Reposted by André Dias

Adriano Bolondi @adrianobolondi.bsky.social · 9d

🚨JOB ALERT🚨

FRIENDS PLEASE SPREAD and RT

We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.

See below 2 calls👇

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Reposted by André Dias

Alfonso Martinez Arias @amartinezarias.bsky.social · 18d

THANK YOU for many years of friendship, support and for sharing your great Science
La Pedrera #Barcelona
#NotInTheGenes #CellsRUs #Cambridge

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Ian Scott @icscott.bsky.social · Jul 27

Great opportunity to join the vibrant developmental biology in Toronto (and boss around me and @wbderry.bsky.social).

jobs.sciencecareers.org/job/673968/p...

Program Head – Developmental, Stem Cell, and Cancer Biology - Toronto (Region), Ontario (CA) job with The Hospital for Sick Children (SickKids) Research Institute | 673968

Provide leadership and mentorship to members of the Developmental, Stem Cell & Cancer and influence the scientific direction of the Research Institute

jobs.sciencecareers.org

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the Node @the-node.bsky.social · Jul 14

Catch up on Development presents… July webinar on early embryogenesis

Featuring talks from @lakshmib02.bsky.social, @dias-andre.bsky.social ‬and @nikhil-mishra.bsky.social

🎥 thenode.biologists.com/catch-up-on-...

@dev-journal.bsky.social #DevBio

Catch up on Development presents… July webinar on early embryogenesis - the Node

Catch up on the Development presents... May webinar, featuring talks from the first authors of Development's 2024 outstanding paper prize finalists.

thenode.biologists.com

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André Dias @dias-andre.bsky.social · Jul 8

Tune in tomorrow if you are interested in understanding how stem cells can be used to make different parts of our body

the Node @the-node.bsky.social · Jul 4

Sign up to attend our next Development presents... webinar on early #embryogenesis, featuring talks from @lakshmib02.bsky.social, @dias-andre.bsky.social ‬and @nikhil-mishra.bsky.social

📅Wed 9 July 15:00BST (UTC+1)

Register here: us02web.zoom.us/webinar/regi...

#DevBio @dev-journal.bsky.social

Development presents... Wednesday 9 July 15:00 BST, chaired by Alex Eve.

Talk 1: Lakshmi Balasubramaniam (Gurdon Institute)
‘Tissue spreading couples matrix remodelling during avian gastrulation’

Talk 2: André Dias (Universitat Pompeu Fabra)
‘Opposing Nodal and Wnt signalling activities govern the emergence of the mammalian body plan’

Talk 3: Nikhil Mishra (Institute of Science and Technology Austria)
‘Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo’

Reposted by André Dias

the Node @the-node.bsky.social · Jun 23

Sign up to attend our next Development presents... webinar on early #embryogenesis, featuring talks from @lakshmib02.bsky.social‬, @dias-andre.bsky.social ‬and @nikhil-mishra.bsky.social.

📅Wed 9 July 15:00BST (UTC+1)

Register here: us02web.zoom.us/webinar/regi...

#DevBio @dev-journal.bsky.social

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Alfonso Martinez Arias @amartinezarias.bsky.social · May 23

In which we discuss the homologies between amphibian and mammalian organizers from the perspective of #gastruloids with special relevance to recently described A and C gastruloids as containing Spemann/Mangold and Trunk/Tail organizers www.sciencedirect.com/science/arti...

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Berta Verd @bertaverd.bsky.social · May 19

Experimental embryology postdoc available in my lab at the @biology.ox.ac.uk @ox.ac.uk working on the evolution of vertebral counts. Reach out if you’re passionate about EvoDevo, enjoy lab work and microscopy and are into or could get into cichlid fishes. Deadline on the 16th June. Please share!

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André Dias @dias-andre.bsky.social · May 16

We've just updated our manuscript to a more 'publishable' version!
www.biorxiv.org/content/10.1...
New details about the role of Wnt in suppressing neural differentiation and fostering a posterior epiblast state, and the temporal effect of Nodal signalling in driving mesendodermal fates

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André Dias @dias-andre.bsky.social · May 16

Great work from Alexandra and Sebastian et al showing how gastrulation is governed downstream of Wnt and Nodal. Two competing transcriptional modules - two opposing signalling activities - orchestrate the emergence of the mammalian body plan.
moving forward, together

Alfonso Martinez Arias @amartinezarias.bsky.social · May 9

Two transcriptional modules that control mammalian #gastrulation that are functionally linked through their GRNs www.biorxiv.org/content/10.1... and paced by interactions between Wnt and Nodal signalling
Great collaboration with S Arnold and K McDole's labs #gastruloids

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Alfonso Martinez Arias @amartinezarias.bsky.social · Mar 21

Difficult to believe that such a community has emerged @ #gastruloids as a model system to explore many aspects of #DevBio. Great to see a room so full of people, curiosity and good Science @prbb.org @upf.edu Thank you to all that have made this possible & of course to the participants

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Alfonso Martinez Arias @amartinezarias.bsky.social · Mar 19

There's increasing evidence that in organoid/embryoids conditions of cells at start of experiments is crucial/ determines outcome. Much to be learnt still. Taking advantage of mouse #gastruloids, two groups explore this here. Important work to calibrate the field www.biorxiv.org/content/10.1...

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bioRxiv Developmental Biology @biorxiv-devbio.bsky.social · Mar 17

N2B27 media formulations influence gastruloid development https://www.biorxiv.org/content/10.1101/2025.03.15.643474v1

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André Dias @dias-andre.bsky.social · Mar 17

Fun collaboration! All the nitty-gritty about N2B27 and gastruloids. Kudos to all the authors, particularly Tina Balayo (¡que va de primero!)

David Turner @gastruloids.bsky.social · Mar 17

New Gastruloid preprint just landed... nice collaboration between our lab, @dias-andre.bsky.social, and @amartinezarias.bsky.social www.biorxiv.org/content/10.1...

N2B27 media formulations influence gastruloid development

Gastruloids are 3D aggregates of pluripotent stem cells grown in suspension culture that mimic many aspects of gastrulation and early axial elongation. The N2B27 basal medium in which mouse gastruloid...

www.biorxiv.org

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Naomi Moris @nmoris.bsky.social · Feb 20

🧫Looking for a PhD to start Autumn 2025? We're recruiting! 🧪

The project will focus on using #embryomodels to explore #development & could cover a range of specific questions. Please RT! 🙏

Apply via the portal, and get more details here: www.crick.ac.uk/careers-stud...

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fredriklanner.bsky.social @fredriklanner.bsky.social · Feb 20

The Lanner lab is recruiting a postdoctoral fellow to continue developing our strategy to generate pluripotent stem cell derived photoreceptors for treatment of blindness. Looking for talented colleague to join our team.
@ki.se
ki.varbi.com/what:job/job...

Postdoktor för framställning av fotoreceptorer från pluripotenta stamceller

Vill du bidra till medicinsk forskning av toppkvalitet? Lanner labbet som tillhör institutionen för klinisk vetenskap, intervention och teknik har utvecklat en metod att producera retinala pigment e

ki.varbi.com

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Development @dev-journal.bsky.social · Feb 13

We are looking for a new Executive Editor on the journal, with @katherine-brown.bsky.social taking on a new role at @biologists.bsky.social. If you're an experienced editor with a love of developmental biology and its community, this could be the job for you. Full details in the link below.

www.biologists.com

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Berta Verd @bertaverd.bsky.social · Feb 5

I am recruiting an #ERC funded PostDoc to work on the evolution of vertebral counts in cichlids. This is an experimental project & will be looking for candidates with experience generating reporter lines, live-imaging and experimental embryology.
Application deadline: 25th Feb.
tinyurl.com/33jbu8fa

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Masaya Hagiwara @masayah.bsky.social · Feb 4

Job Alert!
We are recruiting a postdoc for organoid technology at RIKEN BDR, Japan.

This is a valuable opportunity to work in collaboration with multiple labs, aiming for an advanced integration of developmental biology and engineering.
Please contact!

www.riken.jp/en/careers/r...

Seeking a Research Scientist or Postdoctoral Researcher at Human Biomimetic System RIKEN Hakubi Research Team (K24101)

www.riken.jp

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International Society of Developmental Biology @isdb.bsky.social · Jan 29

‼️The Cell and Developmental Biology Department at UCL is looking for potential candidates for their Research Career Development Fellowships with a potential for tenure-track‼️
And believe it or not, UK Research Councils are not frozen🤗 Please spread the words! www.nature.com/naturecareer...

Research Career Development Fellowships - England job with University College London (UCL) | 12835240

About us Research Career Development Fellowships in the Department of Cell and Developmental Biology, UCL: Expression of Interest for 2024 DEADLI...

www.nature.com

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BaCell3D @bacell3d.bsky.social · Feb 4

We are proud to announce the #BaCell3D Science Bridging Program (SBP)!

SBP aims to connect #organoid researchers around the globe to the Basel community. We offer financial support to selected applicants who can demonstrate motivation for participation and lack of alternative funding sources ⬇️

BaCell 3D | Organoid conference

BaCell 3D is the essential meeting point for researchers and industry professionals dedicated to transforming developmental and biomedical science through cutting-edge in-vitro multicellular systems.

www.bacell3d.com

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Warmflash lab @warmflashlab.bsky.social · Feb 4

Thrilled to share our new preprint from Ye Zhu in the lab. www.biorxiv.org/content/10.1... . We look at the cell fate potential and degree of cadherin switching of human ES cells differentiated to different primitive streak coordinates.

Dependence of cell fate potential and cadherin switching on primitive streak coordinate during differentiation of human pluripotent stem cells

During gastrulation, the primitive streak (PS) forms and begins to differentiate into mesendodermal subtypes. This process involves an epithelial-mesenchymal transition (EMT), which is marked by cadhe...

www.biorxiv.org

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John Wallingford @jbwallingford.bsky.social · Feb 4

Birth defects are the #1 cause of death in the first year of life (🧵). Birth defects kill more than twice as many children as cancer. Birth defects are diseases of developmental biology. Here are CDC statistics for 2021. 1/5

wisqars.cdc.gov/pdfs/leading...

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FMI science @fmiscience.bsky.social · Dec 16

📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...

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Jérôme Gros @jeromegros.bsky.social · Jan 28

Announcing this upcoming conference:

GASTRULATION RELOADED:
Developing, engineering, and evolving the body plan

Join us as we explore the latest research on gastrulation and axis formation/elongation, featuring common, exotic, and synthetic embryos!

📅 14–17 October 2025
📍 Paris, France

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