Adriano Bolondi
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adrianobolondi.bsky.social
Adriano Bolondi
@adrianobolondi.bsky.social
Researcher @crg.eu, previous MeissnerLab @molgen.mpg.de. Interested in how cells and genes make embryos. #EMBO & #MSCA fellow
Reposted by Adriano Bolondi
Outstanding PhD fellowship call OPEN for excellent students.

lacaixafoundation.org/en/doctoral-...

This is for students incoming from outside Spain. And it is VERY well supported (ie at European levels).

If you’re interested in doing a PhD in our lab @irbbarcelona.org, reach out!!!!
Doctoral INPhINIT fellowships - Incoming Call 2026
We grant 30 fellowships for researchers of any nationality who wish to pursue a doctorate in a STEM discipline at research centres of excellence in Spain or Portugal.
www.google.com
November 26, 2025 at 7:43 AM
Reposted by Adriano Bolondi
popEVE is out in Nature Genetics! 🎉
We built a proteome-wide model that combines cross-species and human population variation to rank missense variants by disease severity and help diagnose rare genetic disorders.
rdcu.be/eRu7K
Proteome-wide model for human disease genetics
Nature Genetics - popEVE is a proteome-wide deep generative model to identify and predict pathogenicity of missense mutations causing genetic disorders.
rdcu.be
November 24, 2025 at 1:35 PM
Happy to see Atsuhiro Taguchi's work on genes involved in liver zonation published in Dev @cellpress.bsky.social. Kudos to all authors at @molgen.mpg.de #MeissnerLab #HniszLab. Grateful for the opportunity to help!

www.sciencedirect.com/science/arti...
Single-cell activation screen identifies hepatic maturation regulators with zonal resolution
The maturation of lineage-committed embryonic hepatocytes requires both the timed activation of metabolic gene regulatory networks (GRNs) and silencin…
www.sciencedirect.com
November 21, 2025 at 10:45 AM
Reposted by Adriano Bolondi
check out my journal club on the seminal discovery of local translation in neurons (Kang & Schuman. 1996), and more recently, its activity in neocortex neurodevelopment (Pilaz...Silver. 2023).

cheers to the @erin-schuman.bsky.social & @debbysilver.bsky.social labs!

www.nature.com/articles/s41...
The on-site, on-demand, neuronal gene machine - Nature Reviews Neuroscience
In this Journal Club, Matthew Kraushar discusses a study published in 1996 that found a role for local protein translation in hippocampal synaptic plasticity.
www.nature.com
November 18, 2025 at 6:35 PM
Reposted by Adriano Bolondi
Happy to present the final version of our Cadherin and gastruloid manuscript, online at @cp-cellreports.bsky.social.
www.cell.com/cell-reports...
Initially in BiorXiv (www.biorxiv.org/content/10.1...) 1/12
Cadherins modulate the self-organizing potential of pseudo-embryos
Gastruloids derived from ES cells mimic embryonic patterning through robust self-organization. Mayran et al. uncover that this competence depends on a cadherin switch regulated by Snai1-driven E-cadhe...
www.cell.com
November 17, 2025 at 10:37 AM
Reposted by Adriano Bolondi
"His secret weapons were an unquenchable curiosity and continuing hands-on experimentation at the bench with his beautiful frog embryos and oocytes".

A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
November 7, 2025 at 9:12 PM
Reposted by Adriano Bolondi
@campaslab.bsky.social @jesseveenvliet.bsky.social labs use #gastruloids to explore axial extension in mammalian embryos
www.biorxiv.org/content/10.1...
They find novel mechanisms involving and interplay of proliferation and mechanical constraining.
#NotInTheGenes #CellsRUs
November 6, 2025 at 6:40 AM
Reposted by Adriano Bolondi
Really excited to present the results of a fantastic collaboration with Jesse Veenvliet @jesseveenvliet.bsky.social @mpi-cbg.de @poldresden.bsky.social 🤩

We find a unique mechanism for body axis elongation in mammals, different from other vertebrate species

➡️ www.biorxiv.org/content/10.1...
October 28, 2025 at 8:25 AM
Reposted by Adriano Bolondi
Oh wow - pre-made templates :) - EB
I am happy to present our latest research at the ISSCR 2026 Annual Meeting, taking place in Montréal, Canada on 8-11 July 2026. #ISSCR2026 invt.io/1bxb7uh48oo @isscr.org
I'm speaking at ISSCR 2026 Annual Meeting, join me
Register now
invt.io
October 27, 2025 at 8:15 PM
Reposted by Adriano Bolondi
Wouldn’t it be cool to leverage the throughput of single-cell data to study splicing regulation even when we lack exon resolution? 😀

Here’s the peer-reviewed version of our paper on how we can measure changes in splicing factor activity in virtually any single-cell dataset: doi.org/10.1093/nar/...
Using single-cell perturbation screens to decode the regulatory architecture of splicing factor programs
Abstract. Splicing factors shape the isoform pool of most transcribed genes, playing a critical role in cellular physiology. Their dysregulation is a hallm
doi.org
October 25, 2025 at 2:16 PM
Reposted by Adriano Bolondi
Fully-funded 4-year PhD Opportunities available at the @crick.ac.uk , including a project in our lab on human #embryomodels Feel free to share with anyone interested, and apply through the online portal before 5th November! 👏

www.crick.ac.uk/careers-stud...
Moris Lab | Investigating human trunk development using stem cell-based embryo models
www.crick.ac.uk
October 6, 2025 at 12:03 PM
Reposted by Adriano Bolondi
Two positions available (start Jan/Feb 2026):
- Research Assistant: surl.li/atndnv
- Master Student: surl.li/kgwrni
Deadline: Nov 1st

Please reach out to me ([email protected]) if you want to join us in sunny Barcelona!☀️
October 2, 2025 at 11:00 AM
Reposted by Adriano Bolondi
🚨JOB ALERT🚨

FRIENDS PLEASE SPREAD and RT

We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.

See below 2 calls👇
October 2, 2025 at 11:00 AM
Reposted by Adriano Bolondi
yo scientists awesome opportunity! ⬇️🔥
🚨JOB ALERT🚨

FRIENDS PLEASE SPREAD and RT

We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.

See below 2 calls👇
October 2, 2025 at 11:39 AM
Reposted by Adriano Bolondi
I think everybody knows but Adri is awesome!
🚨JOB ALERT🚨

FRIENDS PLEASE SPREAD and RT

We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.

See below 2 calls👇
October 2, 2025 at 12:34 PM
🚨JOB ALERT🚨

FRIENDS PLEASE SPREAD and RT

We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.

See below 2 calls👇
October 2, 2025 at 11:00 AM
Reposted by Adriano Bolondi
Stay Connected with VGZT Season 7 🌍

From Oct 2025–July 2026, join our online seminar series featuring cutting-edge developmental biology across diverse model organisms. Hear from senior PhD students, postdocs, and PIs as they share their latest discoveries with a global audience.
September 25, 2025 at 8:59 AM
Reposted by Adriano Bolondi
THANK YOU for many years of friendship, support and for sharing your great Science
La Pedrera #Barcelona
#NotInTheGenes #CellsRUs #Cambridge
September 22, 2025 at 9:01 PM
Reposted by Adriano Bolondi
Last days to apply! Cool project, cool cities! :-)

(Please repost! 🙏)
🚨🚨🚨

Please RT!

We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets.

Deadline: 30/09/25👇
www.upf.edu
September 22, 2025 at 7:04 AM
Reposted by Adriano Bolondi
With the group that came together @upf.edu in #Barcelona, celebrating 5 years of exploring, dreaming and discovering. Grateful #NotInTheGenes #CellsRUs
September 22, 2025 at 2:40 PM
Reposted by Adriano Bolondi
Excited to post my first #JobOffer! I am looking for a research technician to help me build new projects from the grounds up at @cabd-upo-csic.bsky.social
We will use medaka to study how organs can be reprogrammed!
Details on how to apply below 👇
#JobOffer #ScienceJobs #EvoDevo #GeneRegulation
September 19, 2025 at 8:53 AM
Reposted by Adriano Bolondi
Ever wondered how to get a gastruloid to grow a head?

The Bulut-Karslioğlu lab figured out that by growing different stem cell aggregates in high and low oxygen and later assembling them, you can get gastruloids with a fully formed neural tube. Check out our "In preprints": doi.org/10.1242/dev....
In preprints: gastruloids get (a)head
A major breakthrough in the field of mammalian embryology is the development of stem-cell based embryo models. Derived from pluripotent stem cells, such as embryonic stem cells or induced pluripotent ...
doi.org
September 16, 2025 at 8:31 AM
Reposted by Adriano Bolondi
🚀 Looking for a Bioinformatician / Data Scientist to join our crew and explore regeneration through single-cell genomics & evolutionary biology! @mpi-bio-fml.bsky.social
📩 Questions? Contact us ✉️
🔗 Apply here: www.mpg.de/25243280/bio...
Bioinformatician / Data Scientist (m/f/d)
Bioinformatician / Data scientist position in the Aztekin Lab focusing on Structural Regeneration and support the working group together with the other members
www.mpg.de
September 15, 2025 at 6:58 AM
Reposted by Adriano Bolondi
🚨 Job Alert: we seek a Lab Manager for @juliabatki.bsky.social's new group (start Mar 2026), which will study cell fate regulation during organ development. Join the Batki's group to drive experiments & lab operations! Apply at: www.fmi.ch/education-ca...
September 2, 2025 at 9:03 AM
Reposted by Adriano Bolondi
I am excited to announce that we are looking for a Lab Manager @fmiscience.bsky.social in Basel. If you want to be part of a growing team investigating development and tissue formation, and are enthusiastic about helping set up a new lab, please check out the role:

www.fmi.ch/education-ca...
September 14, 2025 at 11:46 AM