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Alex Dickson @dicksonlab.bsky.social · 2d

Just gonna leave this here.. youtube.com/shorts/rx3SZ...

The moment that brought Rogers Centre to its feet 🇨🇦

YouTube video by MLB

youtube.com

Alex Dickson @dicksonlab.bsky.social · 7d

Today I asked someone "what shape is your loss?" and I think that could really be a question for everybody

Alex Dickson @dicksonlab.bsky.social · 14d

BatchNorm is evil. Pure Satan spawn sent to destroy us and our projects 👿

Alex Dickson @dicksonlab.bsky.social · Aug 17

I was so proud that I found it 💔. Get it together nyt!

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Reposted by Alex Dickson

acscomp.bsky.social @acscomp.bsky.social · Aug 17

🚨 PLEASE RT 🚨

Are you a comp chem trainee attending Fall ACS in Washington DC? Would you like to expand your network with mentors in industry & academia at the COMP Mentor Lunch?

Fill out this form if you are interested in attending!

forms.gle/dkozpTx3RyK8...

ACS Fall 2025 COMP Mentor Lunch

Please fill out this form if you are a student that would like to come to the COMP Mentor Lunch on Tuesday August 19th at 12:30pm. You will hear back from us with confirmation of your attendance by en...

forms.gle

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Alex Dickson @dicksonlab.bsky.social · Aug 1

A watched model never trains

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Reposted by Alex Dickson

Guillem Simeon @guillemsimeon.bsky.social · Jul 28

Hi network, I am looking for a job in London! Can anyone help me? 😊

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Reposted by Alex Dickson

Heidi Klem @drklemistry.bsky.social · Jul 2

The Klem Lab at LSU is hiring a postdoctoral researcher in computational biochemistry!
Application info: klem-research-group.github.io/join/
♻️ Please share with anyone who might be interested! #chemjobs #postdoc #compchem #biochemistry #enzymes

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Alex Dickson @dicksonlab.bsky.social · Jun 23

Toady Hawk Pro Karter

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Reposted by Alex Dickson

Ed Sherer @hartreefocker.bsky.social · Jun 7

Very excited to be recruiting for an Associate Principal Scientist: Molecular Modeling, Analytical Research & Develop. Our Digital Sciences team is seeing many requests related to influencing formulation design, especially for biologics. #chemjobs #compchem #chemsky jobs.merck.com/us/en/job/R3...

Associate Principal Scientist: Molecular Modeling, Analytical Research & Development job in Rahway, New Jersey, United States of America | jobs at Merck migration

Apply for Associate Principal Scientist: Molecular Modeling, Analytical Research & Development job with Merck migration in Rahway, New Jersey, United States of America. Browse and apply for the jobs a...

jobs.merck.com

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Alex Dickson @dicksonlab.bsky.social · Jun 6

This band has a bright future I can sense it youtu.be/CJ54eImz88w?...

Talking Heads - Psycho Killer (Official Video)

YouTube video by Talking Heads

youtu.be

Reposted by Alex Dickson

Christoph Dellago @chhdellago.bsky.social · Jun 2

Lyapunov instability of a system of WCA disks. Initially, the two systems (blue and red) differ only by 10^-12 in the x-velocities of two particles. The exponential divergence of the trajectories, probed by the configuration space distance, is shown on the right.

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Alex Dickson @dicksonlab.bsky.social · May 21

Our Flexible topology pocket explorer paper is up on ChemRxiv! doi.org/10.26434/che... We run simulations in the B2AR receptor and show that the Flexible Topology particles capture aspects of known B2AR ligands. We also show how FT frames can be used for screening to find new hits!

Flexible topology molecular dynamics uses a set of particles with dynamic charges and sizes to model many ligands in a binding pocket over the course of an MD simulation. This helps consistently model ligand-induced conformational changes in the binding pocket during screening. Individual frames from these simulations can be used as queries to perform virtual screening on databases such as ZINC or HMDB.

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Alex Dickson @dicksonlab.bsky.social · May 19

Lead is sweeter in the short term but you might regret it later..

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Alex Dickson @dicksonlab.bsky.social · May 18

I asked my kids to sing the Canadian national anthem, and they started off to the tune of "O Christmas Tree" 😬

Reposted by Alex Dickson

Ceren Kilinc @cerenkilinc.bsky.social · Apr 8

The latest work from Dickson Lab (@dicksonlab.bsky.social) in collaboration with Pioszak Lab is out!

Check it out for novel insights into the characterization of the two-domain binding mechanism of CGRP and a high-affinity variant ssCGRP to the CGRP receptor:

doi.org/10.1021/acs....

#compchem

Characterization of the Two-Domain Peptide Binding Mechanism of the Human CGRP Receptor for CGRP and the Ultrahigh Affinity ssCGRP Variant

Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide that functions in pain signaling and neuroimmune communication. The CGRP receptor, CGRPR, is a class B GPCR that is a drug target...

doi.org

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Alex Dickson @dicksonlab.bsky.social · Apr 8

Flexing some old vector geometry muscles 😅

Alex Dickson @dicksonlab.bsky.social · Mar 22

🥳

Alex Dickson @dicksonlab.bsky.social · Mar 22

⬆️ ⬆️ Still looking for people who want to work at the intersection of MD and cryo-EM! The position also happens to be privately funded by an alumni donor and guaranteed for 4 years, which sadly, seems important to mention these days. Apply by March 28! (and please share!)

Alex Dickson @dicksonlab.bsky.social · Mar 22

When you find the perfect photo..

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Alex Dickson @dicksonlab.bsky.social · Mar 19

Had a really great time presenting our Flexible Topology work to the folks at Qubit! @qubit-pharma.bsky.social
vimeo.com/992123602

Flexible Topology pocket explorer

A group of ghost particles explore the binding pocket of the beta-2 adrenergic receptor, revealing key features that can be used for virtual screening. Flexible…

vimeo.com

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Reposted by Alex Dickson

Jeremy Berg @jeremymberg.bsky.social · Mar 11

I have confirmation from several sources now that all T32s, many F30s and F31s, and most or all Center awards (P30, P50) have been terminated at Columbia.

This is quite damaging to research and to individuals.

This is pure terrorism and cannot be legal. But litigation will take time...

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Alex Dickson @dicksonlab.bsky.social · Mar 11

I finally did it! 10k unread emails! Wow. What can I say?.. I couldn't have done this alone. It's been a long road. There's so many people I'd like to thank...

A partial screenshot showing exactly 10,000 unread emails on the Mail app. A dramatic failure of communication in the modern era.

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Alex Dickson @dicksonlab.bsky.social · Mar 10

I must be growing as a person, since I just managed to register for the ACS COMP social more than two hours ahead of time. Hope to see you there! urldefense.com/v3/__https:/...

Spring 2025 ACS Comp Social

Join us for our Saturday Social at City Tacos with your fellow ACS COMP members. Don't miss out on this chance to network and socialize with some great food and great company! You must be a registered...

urldefense.com

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Alex Dickson @dicksonlab.bsky.social · Mar 9

Just came across this thread and appreciate all the recs! Already found some great stuff. Thanks!

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