Fee-Fi-Fo-Fum

Keyword: Dudes? I would love to see more non-men (including women, non-binary, intersex, etc scientists) receive the top prize.

Congrats! I would love to talk with you one on one about what it's like to do research in Poland! Sent you a message on LinkedIn!

🔍How do we test for biomarkers?
Usually through blood samples - looking for proteins, cytokines, or other molecules.

It's still early days in the pain field, but blood-based biomarkers may one day help personalize pain treatments.

#HealthResearch #ChronicPain

This! If you read the paper they also were able to ID potential therapeutics based on the biomarkers. Spoiler, the therapeutics were not traditional analgesics. Though something like this is years (maybe even decades) from the clinic, this is huge first step!

3/ DRG are where sensory neurons, including nociceptors, send their signals to the spinal cord.

2/ Here is what the human spinal cord and real DRG look like in humans! Image from human donor and our journal cover in www.jpain.org/article/S152.... White arrows show the DRG, the same clusters shown in the cartoon above.

6 📖 Read the full study here! www.jci.org/articles/vie...

5/ 💡 Toward personalized care:

The study shows that inflammation is the earliest shift in diabetic nerve damage.

Controlling it early may prevent the cascade.

This opens a window for preventive intervention.

4/ 🧠 Why it matters:
This work reveals a progressive cascade:
🧱 Perineurial disruption →
🔥 Immune infiltration →
🧵 Fibrotic remodeling →
📉 Schwann cell loss
Each stage offers a window for intervention.