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Dorien Pastoors

@dpastoors.bsky.social

1.5K followers 960 following 380 posts

Postdoc at DFCI, Boston, USA | molecular biology & hematology 🧫 | data visualization in #ggplot | swimming, running, baking | HemeSky feed

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Dorien Pastoors @dpastoors.bsky.social · Jan 6

Excited to share our preprint on #HemeSky: "MECOM is a master repressor of myeloid differentiation through dose control of CEBPA in acute myeloid leukemia"! @delwelruud.bsky.social and co-authors! www.biorxiv.org/content/10.1... [1/15]

MECOM is a master repressor of myeloid differentiation through dose control of CEBPA in acute myeloid leukemia

Enhancer translocations, due to 3q26 rearrangements, drive out-of-context MECOM expression in an aggressive subtype of acute myeloid leukemia (AML). Direct depletion of MECOM using an endogenous auxin...

www.biorxiv.org

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Dorien Pastoors @dpastoors.bsky.social · 18d

Thanks cansu!!

Dorien Pastoors @dpastoors.bsky.social · 18d

Excited to share that I started as a Postdoctoral Fellow in @tothovalab.bsky.social at @danafarber.bsky.social in Boston! Looking forward to the next years of molecular & myeloid biology in Boston 🤩🌇

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Dorien Pastoors @dpastoors.bsky.social · Jun 28

Thanks Ruben!! 🤩

Dorien Pastoors @dpastoors.bsky.social · Jun 28

Thanks Vijay!!

Dorien Pastoors @dpastoors.bsky.social · Jun 27

Yesterday I successfully defended my PhD thesis!!! It was a fantastic day where I got to celebrate with many colleagues, friends and family (this smile was on my face all day long)

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Dorien Pastoors @dpastoors.bsky.social · Jun 15

hm the last sentence is meant to mean: I hope it will be out soon

Dorien Pastoors @dpastoors.bsky.social · Jun 15

Thanks for the opportunity to present our work at the last day of #EHA2025 🤩 on MECOM as a repressor of CEBPA - also see our recent preprint: www.biorxiv.org/content/10.1... and I very much hope you can stay tuned for the final version soon-ish) #erasmusmcblood #hemesky

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Dorien Pastoors @dpastoors.bsky.social · Jun 14

Thank you!!

Dorien Pastoors @dpastoors.bsky.social · Jun 14

!!!! I am going to watch this before my layman talk - it sounds like i need this to make my thesis defense understandable to my relatives

Dorien Pastoors @dpastoors.bsky.social · Jun 14

My HemeSky feed is now also picking up #EHA2025! bsky.app/profile/dpas...

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Dorien Pastoors @dpastoors.bsky.social · Jun 14

Wait what am I looking at???😂

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Dorien Pastoors @dpastoors.bsky.social · Jun 14

Ahhh i missed this one... Will be joining the next on though !

Dorien Pastoors @dpastoors.bsky.social · Jun 13

🤣 🔥

HemaSphere Journal @hemasphere-journal.bsky.social · Jun 13

Sweaty or not, here we go day 2! The program is 🤩🤩🤩 today.
#EHA2025.

a woman sitting in a chair with the words melting behind her

ALT: a woman sitting in a chair with the words melting behind her

media.tenor.com

Dorien Pastoors @dpastoors.bsky.social · Jun 13

Check out poster 1115 on MBD4 deficiency to model clonal hematopoeisis ⬇️⬇️ #EHA2025 🩸🧪

Sanne Massaar @massaarsanne.bsky.social · Jun 13

This evening I'll be presenting our work on MBD4 knockout as a tool for modelling mutagenesis and clonal outgrowth at the poster session of #EHA2025. Come visit me at PF1115 if you're interested! #Hemesky 🩸🧪

Dorien Pastoors @dpastoors.bsky.social · Jun 13

Congratulations!! 🧪🩸

Erasmus MC Hemostasis and Thrombosis @clotterdam.bsky.social · Jun 13

Well deserved recognition for team Clotterdam's very own @mandylauw.bsky.social #YoungEHA Congratulations Mandy!

HemaSphere Journal @hemasphere-journal.bsky.social · Jun 12

We are HemaSphere proud at #EHA2025, where 2 of our editors received special EHA awards! Congrats to Jan Cools, Ed in Chief, for the education & mentoring award; and to Mandy Lauw, Scientific Ed, for the YoungEHA award. Well deserved 👏 @jancools.bsky.social @mandylauw.bsky.social

Dorien Pastoors @dpastoors.bsky.social · Jun 13

Really enjoying #EHA2025 so far. And also how many people list there BlueSky as social media!! Posts are collected on this HemeSky feed: 🩸🧪https://bsky.app/profile/dpastoors.bsky.social/feed/aaagr4h5mq62a

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Dorien Pastoors @dpastoors.bsky.social · Jun 12

Thank you Sophie !!! ❤️

Dorien Pastoors @dpastoors.bsky.social · Jun 12

Spotted fellow #erasmusmcblood PhD candidate @shordijk.bsky.social at the #EHA wall of fame for her Mobility grant 🤩🤩 Congratulations !! @clotterdam.bsky.social

EHA wall of fame zoomed in to Sophie Hordijk

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Dorien Pastoors @dpastoors.bsky.social · Jun 9

Thank you Duncan!!

Dorien Pastoors @dpastoors.bsky.social · Jun 9

Thank you Cansu!! 😀😀

Dorien Pastoors @dpastoors.bsky.social · Jun 8

Whooo thanks :D

Dorien Pastoors @dpastoors.bsky.social · Jun 8

Thank you Marlies !!

Dorien Pastoors @dpastoors.bsky.social · Jun 8

SUPER excited to share that I got my PhD thesis - thanks to a special delivery from @massaarsanne.bsky.social to Milan!! On the 26th of June, I will defend my thesis at 15:30 CET. You can follow online at eur.cloud.panopto.eu/Panopto/Page... #hemesky

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Dorien Pastoors @dpastoors.bsky.social · Jun 3

#erasmusmcblood #oncode #alpedhuzes #kwf If you would like to make a last-minute donation, anything is still super welcome at www.opgevenisgeenoptie.nl/fundraisers/...

Dorien Pastoors

Ik doe mee aan Alpe d’HuZes omdat ik geloof dat wij samen kunnen werken aan een wereld waarin je niet meer doodgaat aan kanker, wil jij mij steunen?

www.opgevenisgeenoptie.nl

Dorien Pastoors @dpastoors.bsky.social · Jun 3

The total number of participants is 5000 - I was very impressed to see and hear their commitment to raising money for cancer research. Especially in the past years with spreading of misinformation online and budget cuts for research.