David Darrow
@drdaviddarrow.bsky.social
76 followers 49 following 10 posts
Stereotactic functional #neurosurgeon scientist at the University of Minnesota working to translate #neuromodulation into therapies for #pain #neurologic and #psychiatric #diseases
Posts Media Videos Starter Packs
drdaviddarrow.bsky.social
electrodes can stay forever though like anything they can slowly degrade over time! We have some patients with electrodes in their brain for more than 20 years!
drdaviddarrow.bsky.social
And it isn't just about invasive stimulation. It is a tool that we have amongst many and has its uses. But at the same time it sets the stage for validating noninvasive stimulation approaches. We can do invasive stimulation for those who truly need it. #depression
drdaviddarrow.bsky.social
This is the future. The reality of biological #psychiatry. We listen to the patient, create a personalized map of their brain, use algorithms to disrupt stuck networks, and adapt the stimulation over time while continuing our quest to understand those networks.
drdamienfair.bsky.social
Now with PFM, prior cortical stim work by @ziad-nahas.bsky.social for depression could be patient specific.

We developed the end-to-end minimally invasive PACE used by @drdaviddarrow.bsky.social to place electrodes directly on Mike's salience, default, fronto-parietal, and action mode networks.
drdaviddarrow.bsky.social
What is really interesting is that these networks are embedded in the same networks that play a role in executive function and working memory as well as emotional regulation. @alexanderbherman.bsky.social
drdaviddarrow.bsky.social
We have always known that there is the possibility of top-down modulation of pain circuits potentiating the endogenous analgesia network. The question has been how do we even think about trying to target. PFM seems to be a giant leap forward with @drdamienfair.bsky.social @ndosenbach.bsky.social
drdaviddarrow.bsky.social
These patients and many others suffer from central neuropathic pain that often is due to #stroke or #multiplesclerosis or treatment of #trigeminalneuralgia resulting in #anesthesiadolorosa. These are some of the worst pain syndromes on earth!
Reposted by David Darrow
drdamienfair.bsky.social
Alert!!!!

“An Action Networks Model for Pain”

We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it.

👉 thread below 🧵

osf.io/preprints/ps...
drdaviddarrow.bsky.social
Thrilled to drop this with @drdamienfair! Chronic neuropathic pain still disables millions despite meds & implants. We think the answer lies in action circuits
drdaviddarrow.bsky.social
We bid farewell to our amazing postdoc @xinyuanyan.bsky.social and congratulations on her new position with @benhayden.bsky.social @bcmhouston.bsky.social
drdaviddarrow.bsky.social
Congratulations to our new #neurosurgery interns at the #universityofminnesota !
drdaviddarrow.bsky.social
With a thousand people essentially choosing between slot machines, we were able to figure out that anxiety traits and apathy traits provide counterbalance pushing us to either search for better options or stick with what is working, guiding our decisions #universityofminnesota
xinyuanyan.bsky.social
Anxious people tended to explore more, viewing their environment as rapidly changing. In contrast, apathetic individuals explored less and saw changes as random.
check our new paper on BPCNNI 🫰https://sciencedirect.com/science/article/pii/S2451902225000278