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David Shaywitz @dshaywitz.bsky.social · 8h

Yes and - I really think everyone has lost patience with reading almost anything, esp when it's so easy to find pithy distillates in a range of forms. Even most actual essays seem to exist mostly to serve as the basis for podcasts and soc med posts.

David Shaywitz @dshaywitz.bsky.social · 9h

TFW it sinks in that no one actually reads anything. Not when you cognitively recognize this, but when you viscerally understand it and know it to be true.

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David Shaywitz @dshaywitz.bsky.social · 2d

Finally got out three new TR pieces I've been working on:
1. Consumer Health's Digital Convergence - And What's Still Missing: timmermanreport.com/2025/10/cons...
2. Discussion of "Food Intelligence" book timmermanreport.com/2025/10/food...
3. AI Implementation: timmermanreport.com/2025/10/sili...

Consumer Health’s Digital Convergence – And What’s Still Missing - TimmermanReport.com

Consumers are taking increased ownership of their health. As Laura Landro recently described in the Wall Street Journal, this trend is driven in part by necessity — specifically by “a shortage of doct...

timmermanreport.com

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David Shaywitz @dshaywitz.bsky.social · 3d

My latest TR column, discussing progress+ambition in consumer health-esp convergence around "personal health OS." Excited about much of this work, but disappointed by continued reductionist view of health as metric optimization timmermanreport.com/2025/10/consum… @alicecallahan.bsky.social

https://timmermanreport.com/2025/10/consum…

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David Shaywitz @dshaywitz.bsky.social · 9d

I will never forget the day - actually the late evening- they traded Seaver to Reds just before midnight. Devastating.

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Reposted by David Shaywitz

Amanda Carpenter @amandacarpenter.bsky.social · 19d

Each of these companies should be free to fire employees for performance. That can be subjective! No one is entitled to million-dollar paychecks for big news & entertainment jobs.

But when decisions are made to hire and fire to appease a vengeful ruler that’s different. That’s autocracy at work.

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David Shaywitz @dshaywitz.bsky.social · 20d

In addition to whatever this says about wellness, it also speaks to where the audience is perceived to be - it looks like if you want to reach most people impactfully, you need high impact video clips; suspect @zekeemanuel.bsky.social will likely add Youtube, also some kind of podcast...

David Shaywitz @dshaywitz.bsky.social · 20d

Move over Peter Attia and @hubermanlab.com -- looks like @zekeemanuel.bsky.social is leaping (energetically...) into the wellness influencer space! LI announcement ->
linkedin.com/posts/zeke-e...
cc @erictopol.bsky.social @alicecallahan.bsky.social @euanashley.bsky.social

David Shaywitz @dshaywitz.bsky.social · 20d

Move over Peter Attia and @hubermanlab.com -- looks like @zekeemanuel.bsky.social is leaping (energetically...) into the wellness influencer space! LI announcement ->
linkedin.com/posts/zeke-e...
cc @erictopol.bsky.social @alicecallahan.bsky.social @euanashley.bsky.social

David Shaywitz @dshaywitz.bsky.social · 20d

@jvl.bsky.social Quite possibly the only non-shitty thing I've seen all day/week/etc. cc @sonnybunch.bsky.social

Chris Washington 🧛‍♂️ @cwashington.bsky.social · 20d

Japan has a wrestling camp for kids where at the end they have a show match in front of their parents to show off what they learned.

Thought you'd enjoy this.

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Reposted by David Shaywitz

Dr. Lucky Tran @luckytran.com · 20d

IT'S OFFICIAL: Connecticut, Maine, Massachusetts, New Jersey, New York State, Pennsylvania, Rhode Island and New York City have formed the Northeast Public Health Collaborative.

The collaborative will issue their own vaccine recommendations and coordinate public health efforts.

Map of Regional Public Health Coalitions

Northeast Public Health Collaborative (Blue)

West Coast Health Alliance (Yellow)

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David Shaywitz @dshaywitz.bsky.social · 21d

For anyone who, like me, grew up on Woody Allen (and can place lines like "The moose...mingled" & characters like Virgil Starkwell, his interview with Bari Weiss on @thefp.com Honestly pcast will prove, like so many of his films, irresistible - www.thefp.com/p/woody-alle... .

Woody Allen on Life and Death

The film director talks about Soon-Yi, Trump, the Knicks, and why he doesn’t care what you think of him.

www.thefp.com

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Reposted by David Shaywitz

Chris Morrison @chrismorrison.bsky.social · 21d

Yeah but it'll be like $29/share with the fees bsky.app/profile/tech...

Techmeme @techmeme.com · 21d

Sources: StubHub is pricing its US IPO at $23.50/share after marketing a range of $22-$25, giving it an $8.6B market cap, and will trade under the ticker STUB (Bloomberg)

Main Link | Techmeme Permalink

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David Shaywitz @dshaywitz.bsky.social · 21d

Loved this reflective @thebulwark.com essay, “right piece, wrong puzzle” by @jvl.bsky.social. open.substack.com/pub/thebulwa... Connects to themes of contingency I discussed here timmermanreport.com/2024/08/two-... & persisting amid contingency (MCU origin) here timmermanreport.com/2024/05/succ...

Right Piece, Wrong Puzzle

A story about life.

open.substack.com

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David Shaywitz @dshaywitz.bsky.social · 22d

Wisdom bombs on AI and informatics from the inimitable Zak Kohane @harvardmed.bsky.social - always elevating, often sobering, invariably humane.

David Shaywitz @dshaywitz.bsky.social · 22d

Another nice @bostonglobe.com article by @bethteitell.bsky.social, this time about the protein maximizing craze -> www.bostonglobe.com/2025/09/15/l.... Excellent perspective on the science (or lack..) from @erictopol.bsky.social , here: open.substack.com/pub/erictopo... . This, too, will pass…

Protein mania: Why everyone’s eating like a linebacker now - The Boston Globe

Chasing 100 grams a day (or way more), Americans are blending, chugging, and chewing their way through protein-enhanced everything. But at what cost?

www.bostonglobe.com

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David Shaywitz @dshaywitz.bsky.social · 22d

... I'm not sure it's always so obvious to predict which projects are "most promising" - a fact that tends to reveal itself with narrative elegance only after the fact.

David Shaywitz @dshaywitz.bsky.social · 22d

... I would note that there's a very long traditional of exceptional startups being birthed during terrible economic times for the industry the startup is in, and perhaps even oppy to concentrate v best talent around most promising projects... although, as you know if you read my stuff...

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David Shaywitz @dshaywitz.bsky.social · 22d

What's especially maddening about all this is that the underlying science is *amazingly promising* - there have never been more powerful tools better suited to tackling terrible diseases - but like the quote from Right Stuff goes, "No bucks, no Buck Rodgers." That said...

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David Shaywitz @dshaywitz.bsky.social · 22d

and I also worry about impact on attracting future talent to the industry, as noted here

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David Shaywitz @dshaywitz.bsky.social · 22d

Can't tell you how often I'm hearing this...

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David Shaywitz @dshaywitz.bsky.social · 22d

Ofc not perfect comparison, & presumably knowledge workers in lifescience still have options that, while perhaps not ideal, are still more than what seems to be available to many who have lost blue-collar jobs. Also: should be "pointy-head" not "pointed-head" elites. No idea where phrase comes from.

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David Shaywitz @dshaywitz.bsky.social · 22d

@simonbayly.bsky.social while I wouldn't want to carry comparison too far, in some ways (& perhaps this is intentional from an Administration keen to punish pointed-head elites) this feels like white collar version of blue collar despair Springsteen & others describe-just change a few words...

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David Shaywitz @dshaywitz.bsky.social · 22d

It sounds like UK suffered a few recent, acute hits; situation in Boston is portrayed w bleak accuracy in Globe article you link to below - not just the downsizing that's documented, but perhaps more concerning: the massive hit to the usual sense of optimism here - all despite v promising science.

Simon Bayly @simonbayly.bsky.social · 22d

This puts discussions of the London biotech ecosystem into context. Boston is really suffering.

Stephanie @stephy.bsky.social · 22d

“In August, pharmaceutical companies laid off 19,000 people, more than any other sector — up a stunning 142 percent from August 2024”

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Reposted by David Shaywitz

Ensembl @ensembl.org · 23d

Ensembl Beta 13 is live!
Check it out to see if your favourite species made the list-mine did! The Mountain Clouded Yellow was just added (beta.ensembl.org/species/fbf7...)
#Genomics #OpenAccessData

Photo of butterfly, mountain clouded yellow

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Reposted by David Shaywitz

Jonathan Eisen @phylogenomics.bsky.social · 23d

White tailed kite (Elanus leucurus) at #YoloBypass this AM. #birds

White tailed kite perched on a thin bare tree brach. Wings slightly raised. Tail slightly raised. Facing to the right. Blue sky background.

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