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dukegenomics.bsky.social
Duke Genomics
@dukegenomics.bsky.social
47 followers 49 following 22 posts
The Precision Genomics Collaboratory brings together all of the units in Duke focused on genomics research to create a multi-disciplinary community able to tackle challenges in the ever-evolving genomics landscape.
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dukegenomics.bsky.social
Gene therapy is rapidly changes with new technologies and abilities. An article in Nature goes through some of these updates, including work by our own Charlie Gersbach:
www.nature.com/articles/d41...
#genetics #genetherapy #DukeUniversity
From one to many gene therapies
Instead of making one-off treatments, industrialized gene therapy might be able to treat multiple diseases.
www.nature.com
July 7, 2025 at 3:09 PM
dukegenomics.bsky.social
A life well lived. Thank you, David Murdock, for all you have given to Duke University and the MURDOCK Study.
ctsi.duke.edu/news/north-c...
North Carolina Businessman and Philanthropist David Murdock Dies at 102
The Duke Clinical and Translational Science Institute (CTSI) and Duke Health mourn the passing of David H. Murdock, a visionary philanthropist and the namesake of the MURDOCK Study, who died at the ag...
ctsi.duke.edu
June 18, 2025 at 5:52 PM
dukegenomics.bsky.social
Returning research results to clinical study participants has not been the norm, even for those with abnormal findings. The paradigm, though, is shifting, with #ROR becoming not only a scientific responsibility but also an ethical imperative.
medschool.duke.edu/news/data-de...
From Data to Decisions: A Model for Returning Individual Results to Research Participants
Duke researchers have developed a model for how to effectively communicate research results to patients and help empower them towards their health and medical choices.
medschool.duke.edu
June 2, 2025 at 6:31 PM
dukegenomics.bsky.social
Congratulations to Anne West on being awarded a distinguished professorship.
Dr. West is now the George Barth Geller Distinguished Professor of Neurobiology.
today.duke.edu/2025/03/duke...
May 28, 2025 at 8:31 PM
dukegenomics.bsky.social
Congratulations to Greg Crawford on being awarded a distinguished professorship.
Dr. Crawford is the Wilburt C. Davison Distinguished Professor in Pediatrics
today.duke.edu/2025/03/duke...
May 28, 2025 at 8:31 PM
dukegenomics.bsky.social
Congratulations to Gregory Wray for receiving the Gordon G. Hammes Faculty Teaching Award
medschool.duke.edu/news/duke-un...
May 28, 2025 at 8:14 PM
dukegenomics.bsky.social
Shelley Hwang was named on this year's TIME100 Health 2025 List for Cancer Innovators as a pioneer for less invasive treatments for early-stage breast cancer, challenging traditional approaches to surgery and radiation.
oncodaily.com/blog/time100...
Celebrating TIME100 Health 2025’s Most Influential Leaders in Oncology - OncoDaily
Celebrating TIME100 Health 2025’s Most Influential Leaders in Oncology / Abasi Ene-Obong, AmirAli Talasaz, Andre Esteva, Andrea Cercek, Arianna Huffington,
oncodaily.com
May 15, 2025 at 1:38 PM
dukegenomics.bsky.social
Sequencing & Genomic Technologies director Devjanee Swain Lenz will join QIAGEN for a live webinar on May 12 at 11 AM to discuss how to set up your microRNA sequencing project for success.
duke.is/2/3rky
#RNA #sequencing #miRNA
duke.is
May 7, 2025 at 6:41 PM
dukegenomics.bsky.social
The OneDukeGen research study is working to build a healthier future for everyone. By studying blood or saliva for #genetic material collected from 150,000 people, researchers can better understand how our #genes affect our #health.
www.youtube.com/watch?v=9gwD...
OneDukeGen Overview
YouTube video by Duke Center for Precision Health
www.youtube.com
April 30, 2025 at 11:57 AM
dukegenomics.bsky.social
A great opportunity!
dukeopsd.bsky.social Duke OPSD @dukeopsd.bsky.social · Apr 23
Join us for the OPSD Mini Symposium in 1 week!
dukeopsd.bsky.social Duke OPSD @dukeopsd.bsky.social · Apr 2
Join us to recognize 2024 OPSD awardees in person on April 30th from 4-6 PM with remarks from @dukemedschool.bsky.social Dean Mary Klotman and @dukectsi.bsky.social Director Susanna Naggie. All #Duke #PhysicianScientist trainees and faculty are welcome. Food+Drinks duke.qualtrics.com/jfe/form/SV_...
April 23, 2025 at 4:07 PM
dukegenomics.bsky.social
To date, we've given out nearly 100 student pilot grants. Here's how some of them have used these funds to enhance their educational and professional experiences: medschool.duke.edu/blog/pgc-pil...
PGC Pilot Grants Invest in the Future of Science
The Precision Genomics Collaboratory (PGC) is committed to supporting graduate students in scientific and educational efforts that bolster their graduate training experiences.
medschool.duke.edu
April 22, 2025 at 7:39 PM
Reposted by Duke Genomics
dukemedschool.bsky.social
Duke is one of the largest biomedical research enterprises in the country. A cut of this magnitude (15%cap on F&As) would result in thousands of lost jobs at Duke & potentially tens of thousands across NC.
Sources: medschool.duke.edu/about-us/fac... & www.unitedformedicalresearch.org/nih-pdf/?sta...
“This is seismic. Think of a car being built. The direct portion of any NIH grant goes toward the car components, but the indirect payments pay for the assembly line — the facilities, the specialty equipment, the IT structures, and the people. The F&A payments are essential; they are required to do the work.” Colin S. Duckett, PhD, Executive Vice Dean for Basic and Preclinical Science, Duke University School of Medicine, on the devastating effects of the NIH’s cap on indirect grant payments.
February 21, 2025 at 5:00 PM
dukegenomics.bsky.social
Jennifer Cohen helped develop a treatable fetal findings list that uses genetic testing results during pregnancy to treat in utero or prepare to treat immediately following birth. This may improve care for mothers and babies and help deliver more healthy babies.

ctsi.duke.edu/blog/advanci...
Advancing Prenatal, Postnatal Care Through Early Genetic Insight
Pregnancy is exciting and terrifying. Expectant mothers picture their lives when they are finally able to hold the baby growing inside of them in their own arms. But many also worry about making sure ...
ctsi.duke.edu
April 16, 2025 at 4:28 PM
dukegenomics.bsky.social
Congrats to all of the newest distinguished professors at Duke, especially the 4 in the Precision Genomics Collaboratory.
medschool.duke.edu/blog/pgc-fac...
PGC Faculty Among Those Awarded Distinguished Professorships
Duke University has awarded distinguished professorships to 31 faculty members and will recognize them in a ceremony at the Washington Duke Inn on May 14. Among those awarded are four Precision Genomi...
medschool.duke.edu
March 28, 2025 at 6:15 PM
dukegenomics.bsky.social
Join leading experts for a deep dive into the intersection of proteomics, transcriptomics, & Alzheimer’s drug discovery. This webinar explores the data pipeline fueling breakthroughs in personalized medicine, accelerating efficiency, & enhancing accuracy in dementia research.
zoom.us/webinar/regi...
March 26, 2025 at 11:33 AM
dukegenomics.bsky.social
Precision Genomics Collaboratory Director Svati Shah was part of a team that found resting heart rate measured with an investigational watch worn during the Project Baseline Health Study strongly correlated with electrocardiography (ECG), considered the gold standard.
ctsi.duke.edu/news/project...
Project Baseline Study Watch Resting Heart Rate Correlates with ECG
A study found that resting heart rate measured with an investigational watch worn during the Project Baseline Health Study correlated strongly with electrocardiography (ECG), considered the gold stand...
ctsi.duke.edu
March 19, 2025 at 4:31 PM
Reposted by Duke Genomics
natmicrobiol.nature.com
📢Excited to announce a new collection open for submission - The Clinical Microbiome. 💉🦠
Led by @naturecomms.bsky.social with participation from @naturemedicine.bsky.social, @naturemicrobiol.bsky.social, and @commsmed.bsky.social
Details:
www.nature.com/collections/...

#Microsky #MicrobiomeSky
The Clinical Microbiome
This joint Collection invites submissions of cutting-edge translational and clinical research, including microbiome-based diagnostics, therapeutics, ...
www.nature.com
March 11, 2025 at 1:10 PM
Reposted by Duke Genomics
scottsoderling.bsky.social
Excited to share exciting new work from my former postdoc, Il Hwan Kim. His study reveals that SHANK3, an ASD-risk gene, is expressed in brain endothelial cells and plays a crucial role in maintaining tight junction integrity at the blood-brain barrier.

www.nature.com/articles/s41...
Endothelial SHANK3 regulates tight junctions in the neonatal mouse blood-brain barrier through β-Catenin signaling - Nature Communications
This study reveals that SHANK3 deficiency in brain endothelial cells disrupts BBB function during the neonatal period through β-Catenin imbalance, leading to ASD-related neuronal and behavioral abnorm...
www.nature.com
March 11, 2025 at 11:45 PM
Reposted by Duke Genomics
springernature.com
This blog commemorates today's #RareDiseaseDay with a selection of articles, collections, clinical study registrations and blog posts chosen by our publishers: http://spklr.io/633282U5e
A colorful gradient background featuring shades of blue, green, and pink. At the top left, there is a logo for Rare Disease Day. The text in the center reads "I SUPPORT RARE DISEASE DAY" in bold white letters. Below, the date "28 FEB 2025" is displayed, along with a link to learn more at rare diseasesday.org and the hashtag "#RareDiseaseDay" .
February 28, 2025 at 12:45 PM
dukegenomics.bsky.social
Congratulations to Drs. Olabisi and Souma for being elected into the American Society for Clinical Investigation!

medicine.duke.edu/news/two-duk...
Two Duke Nephrologists Elected to American Society for Clinical Investigation
Two Duke Department of Medicine faculty members, physician-scientists Opeyemi A. Olabisi, MD, PhD, and Tomokazu Souma, MD, PhD, are among the 2025 researchers elected to the American Society for Clini...
medicine.duke.edu
February 26, 2025 at 1:13 PM
dukegenomics.bsky.social
Pulse oximetry monitors oxygen levels in patients, but for those with darker skin tones, the equipment isn't always reliable. A. Ian Wong and team received a $3.4M to develop methods and technology to improve the accuracy of pulse oximetry. ctsi.duke.edu/blog/new-gra...
New Grant to Address Hidden Hypoxemia
Pulse oximetry has long been trusted as a key diagnostic tool. However, for patients with darker skin tones, this technology may not be accurate. A new grant aims to fix that.
ctsi.duke.edu
February 26, 2025 at 12:38 PM
dukegenomics.bsky.social
Researchers find a master #epigenetic switch that activates silenced genes to compensate for their missing counterparts in a rare genetic disease called #Prader-Willi syndrome
pratt.duke.edu/news/crispr-...
#epigenome #genomics #CRISPR
Activating Complex Regions of the Genome to Treat Rare Diseases | Duke Pratt School of Engineering
Researchers find a master epigenetic switch that activates silenced genes to compensate for their missing counterparts in a rare genetic disease called Prader-Willi syndrome
pratt.duke.edu
February 18, 2025 at 11:56 AM
dukegenomics.bsky.social
Genomics and Precision Health, in the words of PGC Director, Svati Shah:
"That’s my dream: Instead of the trial-and-error way we currently practice medicine, we’ll have a much more precise way that we deliver care and, hopefully, prevent disease entirely." medschool.duke.edu/news/what-co...
What Comes Next: Genomics and Precision Health
Dr. Svati Shah, a leader in cardiovascular genetics at Duke, directs the OneDukeGen program, aiming to sequence 150,000 patients to identify actionable genetic variants. Her vision is a future where g...
medschool.duke.edu
January 29, 2025 at 11:38 AM
dukegenomics.bsky.social
An artificial womb holds promise for helping premature babies face less health risks. New research from Duke and CHOP show that in animal models, the EXTEND artificial womb model is both safe and effective. Read more: medschool.duke.edu/blog/extendi...
EXTENDing Hope: Artificial Wombs for Safer Neonatal Development
For expectant mothers, going into labor early can be terrifying. Premature babies are at an increased risk for serious health problems. The earlier a baby is born, the higher risk of health challenges...
medschool.duke.edu
January 16, 2025 at 2:32 PM
dukegenomics.bsky.social
Early in her career, surgical oncologist Shelley Hwang questioned the practice of treating patients diagnosed with certain breast cancer with mastectomies or lumpectomies. Now, she's showing less aggressive alternatives may be available
medschool.duke.edu/stories/reac...
Reaching New Heights in Cancer Care
Patients with ductal carcinoma in situ (DCIS) are usually treated with surgery and radiation, even though it may not develop into invasive breast cancer. Dr. Shelley Hwang recently presented a study s...
medschool.duke.edu
January 13, 2025 at 5:55 PM