DZNE research center
@dzne.science
Dedicated to advancing the scientific understanding of neurodegenerative diseases - from mechanisms to diagnosis, therapy, and prevention (such as AD, PD or ALS).
🔗 Imprint: https://dzne.de/en/imprint
🔗 Data Protection: https://dzne.de/en/data-protection/
🔗 Imprint: https://dzne.de/en/imprint
🔗 Data Protection: https://dzne.de/en/data-protection/
New paper out: Krankheitsmodifizierende Therapie mit Lecanemab bei früher Alzheimer-Demenz | Disease-modifying therapy with lecanemab for early Alzheimer's dementia: Hansen, Niels; Wiltfang, Jens
Fortschritte der Neurologie, Psychiatrie Vol. 93, no. 11, p. 453 -… | Thanks for sharing #dzne #papers
Fortschritte der Neurologie, Psychiatrie Vol. 93, no. 11, p. 453 -… | Thanks for sharing #dzne #papers
Krankheitsmodifizierende Therapie mit Lecanemab bei früher Alzheimer-Demenz | Disease-modifying therapy with lecanemab for early Alzheimer's dementia
Hansen, Niels; Wiltfang, Jens
Fortschritte der Neurologie, Psychiatrie Vol. 93, no. 11, p. 453 - 460
dlvr.it
November 29, 2025 at 11:55 AM
New paper out: Progression to Parkinson's dementia is not modulated by genetic risk variants for Alzheimer's or Parkinson's disease.: Parveen, Kayenat; Ross, J Alexander; van der Wurp, Hendrik; et al.
Journal of Parkinson's Disease Vol. 15, no. 7, p. 1304 - 1311 | Thanks for sharing #dzne #papers
Journal of Parkinson's Disease Vol. 15, no. 7, p. 1304 - 1311 | Thanks for sharing #dzne #papers
Progression to Parkinson's dementia is not modulated by genetic risk variants for Alzheimer's or Parkinson's disease.
Parveen, Kayenat; Ross, J Alexander; van der Wurp, Hendrik; et al.
Journal of Parkinson's Disease Vol. 15, no. 7, p. 1304 - 1311
dlvr.it
November 29, 2025 at 11:55 AM
New paper out: The E193K LRRK2 mutation interferes with the autophagosome processing through the impairment of the LRRK2-Dynein-1 complex.: Redl, Stefan; Zweydorf, Felix; Gloeckner, Christian J; et al.
Scientific reports Vol. 15, no. 1, p. 39117 | Thanks for sharing #dzne #papers
Scientific reports Vol. 15, no. 1, p. 39117 | Thanks for sharing #dzne #papers
The E193K LRRK2 mutation interferes with the autophagosome processing through the impairment of the LRRK2-Dynein-1 complex.
Redl, Stefan; Zweydorf, Felix; Gloeckner, Christian J; et al.
Scientific reports Vol. 15, no. 1, p. 39117
dlvr.it
November 29, 2025 at 11:55 AM
New paper out: [18F]SiTATE-PET/CT for detection of pheochromocytomas and paragangliomas: comparison of biochemical secretion, genotype and imaging metrics.: Onkes, Meike; Dahlmann, Paul; Gesenhues, Alena; et al.
European journal of nuclear medicine and molecular… | Thanks for sharing #dzne #papers
European journal of nuclear medicine and molecular… | Thanks for sharing #dzne #papers
[18F]SiTATE-PET/CT for detection of pheochromocytomas and paragangliomas: comparison of biochemical secretion, genotype and imaging metrics.
Onkes, Meike; Dahlmann, Paul; Gesenhues, Alena; et al.
European journal of nuclear medicine and molecular imaging Vol. 52, no. 13, p. 5175 - 5188
dlvr.it
November 28, 2025 at 11:58 AM
New paper out: Assessing a Stimulator Modification for Simultaneous Noninvasive Auricular Vagus Nerve Stimulation and MRI.: Teckentrup, Vanessa; Ludwig, Mareike; Seibt, Janis; et al.
Journal of neuroimaging Vol. 35, no. 6, p. e70098 | Thanks for sharing #dzne #papers
Journal of neuroimaging Vol. 35, no. 6, p. e70098 | Thanks for sharing #dzne #papers
Assessing a Stimulator Modification for Simultaneous Noninvasive Auricular Vagus Nerve Stimulation and MRI.
Teckentrup, Vanessa; Ludwig, Mareike; Seibt, Janis; et al.
Journal of neuroimaging Vol. 35, no. 6, p. e70098
dlvr.it
November 28, 2025 at 11:58 AM
New paper out: Neues zur Blutbiomarker gestützten Frühdiagnostik der Vorstufen einer Alzheimer-Demenz | News on blood biomarker-based early diagnosis of the preliminary stages of Alzheimer's dementia: Hansen, Niels; Wiltfang, Jens
Fortschritte der Neurologie,… | Thanks for sharing #dzne #papers
Fortschritte der Neurologie,… | Thanks for sharing #dzne #papers
Neues zur Blutbiomarker gestützten Frühdiagnostik der Vorstufen einer Alzheimer-Demenz | News on blood biomarker-based early diagnosis of the preliminary stages of Alzheimer's dementia
Hansen, Niels; Wiltfang, Jens
Fortschritte der Neurologie, Psychiatrie Vol. 93, no. 11, p. 446 - 452
dlvr.it
November 28, 2025 at 11:58 AM
Neurons that dampen electrical brain activity influence emotional memories more than expected.
DZNE's @sabinekrabbe.bsky.social and colleagues report in @nature.com Communications that these cells are key for how memories form - offering new clues to anxiety and PTSD.
👉 www.dzne.de/en/im-fokus/...
DZNE's @sabinekrabbe.bsky.social and colleagues report in @nature.com Communications that these cells are key for how memories form - offering new clues to anxiety and PTSD.
👉 www.dzne.de/en/im-fokus/...
November 28, 2025 at 10:23 AM
Neurons that dampen electrical brain activity influence emotional memories more than expected.
DZNE's @sabinekrabbe.bsky.social and colleagues report in @nature.com Communications that these cells are key for how memories form - offering new clues to anxiety and PTSD.
👉 www.dzne.de/en/im-fokus/...
DZNE's @sabinekrabbe.bsky.social and colleagues report in @nature.com Communications that these cells are key for how memories form - offering new clues to anxiety and PTSD.
👉 www.dzne.de/en/im-fokus/...
You'd better be quick about this one.
Join us for BonnBrain 2026!
The official deadline for abstract submission is December 15th, but we only have a few slots left and might be sold out before the deadline.
Apply quickly 👉 bonnbrain.de to be considered by our Scientific Committee!
The official deadline for abstract submission is December 15th, but we only have a few slots left and might be sold out before the deadline.
Apply quickly 👉 bonnbrain.de to be considered by our Scientific Committee!
November 27, 2025 at 7:51 AM
You'd better be quick about this one.
🏆 Congrats Lars Lannfelt! The Swedish #Alzheimer’s researcher, who paved the way for the drug #Lecanemab has received the "Hartwig Piepenbrock-DZNE Prize". The award recognizes exceptional research on neurodegenerative diseases.
👉 www.linkedin.com/posts/dzne_d...
👉 www.linkedin.com/posts/dzne_d...
November 20, 2025 at 8:02 PM
🏆 Congrats Lars Lannfelt! The Swedish #Alzheimer’s researcher, who paved the way for the drug #Lecanemab has received the "Hartwig Piepenbrock-DZNE Prize". The award recognizes exceptional research on neurodegenerative diseases.
👉 www.linkedin.com/posts/dzne_d...
👉 www.linkedin.com/posts/dzne_d...
New paper out: Region-specific drivers of CSF mobility measured with MRI in humans.: Hirschler, Lydiane; Runderkamp, Bobby A; Decker, Andreas; et al.
Nature neuroscience Vol. 28, no. 11, p. 2392 - 2401 Thanks for sharing! #dzne #papers
Nature neuroscience Vol. 28, no. 11, p. 2392 - 2401 Thanks for sharing! #dzne #papers
Region-specific drivers of CSF mobility measured with MRI in humans.
Hirschler, Lydiane; Runderkamp, Bobby A; Decker, Andreas; et al.
Nature neuroscience Vol. 28, no. 11, p. 2392 - 2401
dlvr.it
November 19, 2025 at 12:26 PM
New paper out: Amyloid‐β Seeds in Alzheimer's Disease: Research Challenges and Implications: Beschorner, Natalie; Xu, Ying; Jucker, Mathias; et al.
Journal of neurochemistry Vol. 169, no. 11, p. e70267 Thanks for sharing! #dzne #papers
Journal of neurochemistry Vol. 169, no. 11, p. e70267 Thanks for sharing! #dzne #papers
Amyloid‐β Seeds in Alzheimer's Disease: Research Challenges and Implications
Beschorner, Natalie; Xu, Ying; Jucker, Mathias; et al.
Journal of neurochemistry Vol. 169, no. 11, p. e70267
dlvr.it
November 19, 2025 at 12:26 PM
New paper out: Compound Muscle Action Potential (CMAP) Amplitude Trajectories and Pattern in Adults with 5q-Spinal Muscular Atrophy Receiving Nusinersen Therapy: A Multicenter, Binational Observational Study.: Bjelica, Bogdan; Wohnrade, Camilla; Osmanovic, Alma; et… Thanks for sharing! #dzne #papers
Compound Muscle Action Potential (CMAP) Amplitude Trajectories and Pattern in Adults with 5q-Spinal Muscular Atrophy Receiving Nusinersen Therapy: A Multicenter, Binational Observational Study.
Bjelica, Bogdan; Wohnrade, Camilla; Osmanovic, Alma; et al.
European journal of neurology Vol. 32, no. 11, p. e70405
dlvr.it
November 19, 2025 at 12:26 PM
New paper out: Compound Muscle Action Potential (CMAP) Amplitude Trajectories and Pattern in Adults with 5q-Spinal Muscular Atrophy Receiving Nusinersen Therapy: A Multicenter, Binational Observational Study.: Bjelica, Bogdan; Wohnrade, Camilla; Osmanovic, Alma; et… Thanks for sharing! #dzne #papers
New paper out: Cognitive performance in patients with ischemic stroke and additional myocardial injury - results from the multicenter prospective observational PRAISE study.: von Rennenberg, Regina; Litmeier, Simon; Szabo, Kristina; et al.
Neurological research and… Thanks for sharing! #dzne #papers
Neurological research and… Thanks for sharing! #dzne #papers
Cognitive performance in patients with ischemic stroke and additional myocardial injury - results from the multicenter prospective observational PRAISE study.
von Rennenberg, Regina; Litmeier, Simon; Szabo, Kristina; et al.
Neurological research and practice Vol. 7, no. 1, p. 84
dlvr.it
November 18, 2025 at 12:28 PM
New paper out: VGF AQEE- and GGEE-peptides differentiate between dementia types.: Noli, B.; Muqaku, B.; Gouda, M.; et al.
Journal of neurology Vol. 272, no. 11, p. 745 Thanks for sharing! #dzne #papers
Journal of neurology Vol. 272, no. 11, p. 745 Thanks for sharing! #dzne #papers
VGF AQEE- and GGEE-peptides differentiate between dementia types.
Noli, B.; Muqaku, B.; Gouda, M.; et al.
Journal of neurology Vol. 272, no. 11, p. 745
dlvr.it
November 18, 2025 at 12:28 PM
New paper out: Modeling Alzheimer's disease: Bayesian copula graphical model from demographic, cognitive, and neuroimaging data.: Vogels, Lucas; Mohammadi, Reza; Schoonhoven, Marit; et al.
Journal of Alzheimer's disease Vol. 108, no. 1_suppl Thanks for sharing! #dzne #papers
Journal of Alzheimer's disease Vol. 108, no. 1_suppl Thanks for sharing! #dzne #papers
Modeling Alzheimer's disease: Bayesian copula graphical model from demographic, cognitive, and neuroimaging data.
Vogels, Lucas; Mohammadi, Reza; Schoonhoven, Marit; et al.
Journal of Alzheimer's disease Vol. 108, no. 1_suppl
dlvr.it
November 17, 2025 at 12:32 PM
New paper out: A computational ontology framework for the synthesis of multi-level pathology reports from brain MRI scans.: Singh, Devesh; Grazia, Alice; Reiz, Achim; et al.
Journal of Alzheimer's disease Vol. 108, no. 1_suppl Thanks for sharing! #dzne #papers
Journal of Alzheimer's disease Vol. 108, no. 1_suppl Thanks for sharing! #dzne #papers
A computational ontology framework for the synthesis of multi-level pathology reports from brain MRI scans.
Singh, Devesh; Grazia, Alice; Reiz, Achim; et al.
Journal of Alzheimer's disease Vol. 108, no. 1_suppl
dlvr.it
November 17, 2025 at 12:32 PM
New paper out: How can Alzheimer's disease blood-based biomarkers reach clinical practice?: Perneczky, Robert; Quevenco, Frances-Catherine; Hendrix, James; et al.
Alzheimer's & dementia / Diagnosis, assessment & disease monitoring Vol. 17, no. 4, p. e70207 Thanks for sharing! #dzne #papers
Alzheimer's & dementia / Diagnosis, assessment & disease monitoring Vol. 17, no. 4, p. e70207 Thanks for sharing! #dzne #papers
How can Alzheimer's disease blood-based biomarkers reach clinical practice?
Perneczky, Robert; Quevenco, Frances-Catherine; Hendrix, James; et al.
Alzheimer's & dementia / Diagnosis, assessment & disease monitoring Vol. 17, no. 4, p. e70207
dlvr.it
November 17, 2025 at 12:32 PM
New paper out: Heterogeneous plasticity of amygdala interneurons in associative learning and extinction: Favila, Natalia; Capece Marsico, Jessica; Pacheco, Catarina M.; et al.
Nature Communications Vol. 16, no. 1, p. 9926
Nature Communications Vol. 16, no. 1, p. 9926
Heterogeneous plasticity of amygdala interneurons in associative learning and extinction
Favila, Natalia; Capece Marsico, Jessica; Pacheco, Catarina M.; et al.
Nature Communications Vol. 16, no. 1, p. 9926
pub.dzne.de
November 14, 2025 at 12:32 PM
New paper out: Heterogeneous plasticity of amygdala interneurons in associative learning and extinction: Favila, Natalia; Capece Marsico, Jessica; Pacheco, Catarina M.; et al.
Nature Communications Vol. 16, no. 1, p. 9926
Nature Communications Vol. 16, no. 1, p. 9926
🥂 Congrats to Marie Homeyer (RG Harald Prüß) on receiving the Felgenhauer Research Award 2025! Her dissertation at DZNE and Charité provides important insights for further development of autoantibody-specific NMDAR-CAAR T-cell therapy and offers valuable insights for current immunotherapy research.
Congratulations to Marie Alice Homeyer on winning the Felgenhauer Research Award 2025! With her dissertation at @dzne.science and #Charité Berlin, she made an essential contribution to the development of autoantibody-specific NMDAR-CAAR T-cell therapy. #dgnkongress2025 #neuroskyence 📷Claudius Pflug
November 14, 2025 at 8:42 AM
🥂 Congrats to Marie Homeyer (RG Harald Prüß) on receiving the Felgenhauer Research Award 2025! Her dissertation at DZNE and Charité provides important insights for further development of autoantibody-specific NMDAR-CAAR T-cell therapy and offers valuable insights for current immunotherapy research.
Reposted by DZNE research center
🎉🏅We congratulate 🌟Zeynep Dokuzluoglu🌟 (German Center for #Neurodegenerative Diseases, #DZNE, Dresden) on winning the FEBS Letters #PosterPrize at the EMBO/EMBL Symposium on #organoids, held in Heidelberg, Germany!
#EESOrgan
@events.embl.org
#EESOrgan
@events.embl.org
November 13, 2025 at 12:17 PM
🎉🏅We congratulate 🌟Zeynep Dokuzluoglu🌟 (German Center for #Neurodegenerative Diseases, #DZNE, Dresden) on winning the FEBS Letters #PosterPrize at the EMBO/EMBL Symposium on #organoids, held in Heidelberg, Germany!
#EESOrgan
@events.embl.org
#EESOrgan
@events.embl.org
Congratulations to DZNE’s Martin Dichgans, Brit Mollenhauer, @joachimschultze.bsky.social and Mikael Simons for their notable scientific impact and ongoing contributions to advancing our understanding of neurodegenerative diseases.
They are listed as Highly Cited Researchers 2025 by @clarivate.com
They are listed as Highly Cited Researchers 2025 by @clarivate.com
November 13, 2025 at 9:12 AM
Congratulations to DZNE’s Martin Dichgans, Brit Mollenhauer, @joachimschultze.bsky.social and Mikael Simons for their notable scientific impact and ongoing contributions to advancing our understanding of neurodegenerative diseases.
They are listed as Highly Cited Researchers 2025 by @clarivate.com
They are listed as Highly Cited Researchers 2025 by @clarivate.com
Reposted by DZNE research center
Out now: Favila, Capece Marsico et al. 2025, Nature Communications: Using longitudinal deep-brain imaging, we report that amygdala interneurons exhibit complex and heterogeneous plasticity during associative learning, at both the single-cell and population level.
👉 www.nature.com/articles/s41...
👉 www.nature.com/articles/s41...
Heterogeneous plasticity of amygdala interneurons in associative learning and extinction - Nature Communications
In this study, the authors uncover how diverse inhibitory interneurons in the amygdala flexibly contribute to fear and safety learning, revealing a key role for inhibition in emotional memory and adap...
www.nature.com
November 12, 2025 at 6:55 PM
Out now: Favila, Capece Marsico et al. 2025, Nature Communications: Using longitudinal deep-brain imaging, we report that amygdala interneurons exhibit complex and heterogeneous plasticity during associative learning, at both the single-cell and population level.
👉 www.nature.com/articles/s41...
👉 www.nature.com/articles/s41...
Reposted by DZNE research center
Latest from the lab: Laura Haetzel finds that excitatory transmission from auditory thalamus to tail of striatum is accompanied by a sparse inhibitory projection. This allows for state-dependent control of striatal output.
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
Inhibitory inputs from thalamus promote resilient spiking in tail of striatum
Neuroscience; Sensory neuroscience
www.cell.com
November 11, 2025 at 3:04 PM
Latest from the lab: Laura Haetzel finds that excitatory transmission from auditory thalamus to tail of striatum is accompanied by a sparse inhibitory projection. This allows for state-dependent control of striatal output.
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
Reposted by DZNE research center
Join us for 𝗦𝘁𝗲𝗺 𝗖𝗲𝗹𝗹𝘀 𝗶𝗻 𝗡𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲, 𝟮𝟱𝘁𝗵-𝟮𝟳𝘁𝗵 𝗼𝗳 𝗙𝗲𝗯𝗿𝘂𝗮𝗿𝘆, 𝟮𝟬𝟮𝟲 in Tübingen, Germany.
Register here until 30th of November:
👉 www.stemcelltuebingen.com 👈
Please repost and spread the news!
@dzne.science
@hih-tuebingen.bsky.social
@tueneurocampus.bsky.social
@unituebingen.bsky.social
Register here until 30th of November:
👉 www.stemcelltuebingen.com 👈
Please repost and spread the news!
@dzne.science
@hih-tuebingen.bsky.social
@tueneurocampus.bsky.social
@unituebingen.bsky.social
November 6, 2025 at 7:31 AM
Join us for 𝗦𝘁𝗲𝗺 𝗖𝗲𝗹𝗹𝘀 𝗶𝗻 𝗡𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲, 𝟮𝟱𝘁𝗵-𝟮𝟳𝘁𝗵 𝗼𝗳 𝗙𝗲𝗯𝗿𝘂𝗮𝗿𝘆, 𝟮𝟬𝟮𝟲 in Tübingen, Germany.
Register here until 30th of November:
👉 www.stemcelltuebingen.com 👈
Please repost and spread the news!
@dzne.science
@hih-tuebingen.bsky.social
@tueneurocampus.bsky.social
@unituebingen.bsky.social
Register here until 30th of November:
👉 www.stemcelltuebingen.com 👈
Please repost and spread the news!
@dzne.science
@hih-tuebingen.bsky.social
@tueneurocampus.bsky.social
@unituebingen.bsky.social
Congratulations to Dr Dr Ahmad Aziz, who has been appointed to a joint professorship at the @unibonn.bsky.social and the DZNE! The appointment was made within the framework of the “Jülich Model”, which enables joint professorial appointments across institutions.
More 👉 www.dzne.de/en/im-fokus/...
More 👉 www.dzne.de/en/im-fokus/...
November 5, 2025 at 1:38 PM
Congratulations to Dr Dr Ahmad Aziz, who has been appointed to a joint professorship at the @unibonn.bsky.social and the DZNE! The appointment was made within the framework of the “Jülich Model”, which enables joint professorial appointments across institutions.
More 👉 www.dzne.de/en/im-fokus/...
More 👉 www.dzne.de/en/im-fokus/...