Lightnews — Scholar-powered news

Emmajay Sutherland @emmajays.bsky.social · 12d

Hi Jochen! Using Glycounter (from RRG), we can classify MS/MS scans as 'likely glyco' from the presence of >8 oxonium ions. Here, NP+MAX yields around 60% of MS/MS scans with oxonium ions whereas neat plasma (NP0) has 4%.

4

Emmajay Sutherland @emmajays.bsky.social · 15d

Can nanoparticles help us probe the glycoproteome?

The new pre-print from @riley-research.bsky.social seeks to answer this question using the Proteograph technology from Seer Inc.

Check out this lovely study on glycoproteins NP-enriched from biofluids here: chemrxiv.org/engage/chemr...

3 9

Reposted by Emmajay Sutherland

Nick Riley @nmriley.bsky.social · Jul 23

@riley-research.bsky.social had a great time catching up with local research at the Cascadia Proteomics Symposium last week. The lineup featured talks from Katie Kothlow and Haley Schramm, and a lightning talk/poster from @emmajays.bsky.social

Congrats to Emmajay for her 2nd-place poster award too!

3 12

Emmajay Sutherland @emmajays.bsky.social · Jun 3

It was great to meet you yesterday! 😊 It was nice, if unexpected, to hear a friendly familiar accent

1

Emmajay Sutherland @emmajays.bsky.social · Mar 29

Had an amazing time at the Glycobiology Gordon Research Seminar and Conference in Italy! 🇮🇹 As a first-time attendee, I appreciated meeting so many incredible scientists from across the world. We spent the days talking about carbohydrates, and the nights eating them. 🍝 #Glycobiology #Glycotime

2 12

Reposted by Emmajay Sutherland

Nick Riley @nmriley.bsky.social · Mar 26

GlyCounter (and pre-print) from the @riley-research.bsky.social is now out to help inspect raw MS data for glycan-specific ions.

Congrats to first author Katie Kothlow for leading this and to all RRG members who helped test GlyCounter's utility for numerous datasets! This was a great team effort.

bioRxivpreprint @biorxivpreprint.bsky.social · Mar 25

Extracting informative glycan-specific ions from glycopeptide MS/MS spectra with GlyCounter https://www.biorxiv.org/content/10.1101/2025.03.24.645139v1

3 7 18

Emmajay Sutherland @emmajays.bsky.social · Mar 23

Great talk yesterday!! 👏

1

Reposted by Emmajay Sutherland

ELIXIR-Netherlands @elixir-nl.bsky.social · Mar 11

Today we celebrate the 100th birthday of Margaret Dayhoff, founder of bioinformatics and creator of the first sequence databases. Her legacy inspires generations of scientists in bioinformatics, proteomics, and computational biology.

bit.ly/4hmTdLl

#WomenInScience #Bioinformatics #Proteomics

A Special Software Issue in Celebration of Margaret Dayhoff’s 100th Birthday

pubs.acs.org

22 31

Reposted by Emmajay Sutherland

Science Friday @scifri.bsky.social · Mar 11

A recent study found that cervical cancer deaths in young women have plummeted since the introduction of the human papillomavirus vaccine.

As Cervical Cancer Deaths Plummet, Experts Credit HPV Vaccine

HPV can cause a variety of cancers, including cervical. New mortality data for women under 25 point to the success of the HPV vaccine.

buff.ly

360 4.1K 19K

Reposted by Emmajay Sutherland

Katie Mack @astrokatie.com · Mar 11

The erosion of trust in science & scientists — sometimes due to complex social/historical factors but often deliberately perpetrated by charlatans — has tragic, deadly consequences, and, if unchecked, is an existential threat to society.

The Atlantic @theatlantic.com · Mar 11

"The vaccination has stuff we don't trust," said the father of the 6-year-old girl who died from measles at the end of last month. Tom Bartlett visited with a family confronting an unthinkable tragedy:

The Texas Girl Who Died From Measles

Her father tells her story.

www.theatlantic.com

42 370 1.6K

Reposted by Emmajay Sutherland

Nick Riley @nmriley.bsky.social · Mar 6

Nick Riley @nmriley.bsky.social · Mar 1

The Stand Up for Science rally has been scheduled for March 7th from 12-3PM at Seattle Center (by the mural amphitheater).

6 7

Reposted by Emmajay Sutherland

Nick Riley @nmriley.bsky.social · Mar 5

I am excited to discuss our efforts in @riley-research.bsky.social to help streamline glycoproteomics methods at the @glygen.bsky.social webinar next week!

SfG @sfglycobiology.bsky.social · Feb 26

Exciting @glygen.bsky.social webinar coming up! On March 11th, 2025, 10 ET @nmriley.bsky.social will present his research and progress in the development of tools to explore complex glycoproteomics data. Info on the flyer and in the link below ⬇️ 👍

wiki.glygen.org/GlyGen_Webin...

Screenshot of the GlyGen Webinar flyer adertising Dr Nicholas Riley's (in the photo) webinar on Mar 11th 2025

5 16

Reposted by Emmajay Sutherland

Nick Riley @nmriley.bsky.social · Mar 2

Despite current events, @riley-research.bsky.social enjoyed @us-hupo.bsky.social last week!

Connecting w/ colleagues was an antidote for the frustration that occupies a lot of my brain space these days

Thanks for the continual motivation to pursue good science and support scientists however we can

1 4 21

Reposted by Emmajay Sutherland

Amanda Smythers @amandalsmythers.bsky.social · Feb 25

My favorite takeaway from #USHUPO2025 so far?! Building a business is not too different from building a lab. Huge thanks to @lindsaykpino.com & @nmriley.bsky.social for hosting a phenomenal workshop on the business of starting a lab!!!

4 21

Reposted by Emmajay Sutherland

Jaclyn A. Siegel, PhD @jacasiegel.bsky.social · Feb 11

Happy International Day of Women in Science. The National Science Foundation’s list of flagged words includes both “Women” and “Female.”

29 1K 2.3K

Emmajay Sutherland @emmajays.bsky.social · Jan 24

The final chapter of my PhD thesis is officially published!😄 It's a true reflection of collaborative research and I can't thank my PhD supervisor, Clarissa Melo Czekster, enough. Of course, the figures feature the most amount of pink probably seen in a research journal so please enjoy! rdcu.be/d7owS

2

Reposted by Emmajay Sutherland

Nikolai Slavov @slavov-n.bsky.social · Jan 2

The heterogeneity of HeLa cell-lines undermines reproducibility.

HeLa cells were obtained without informed consent.

==> Researchers should avoid using HeLa cells unless required by a special justification.

1 3 11

Emmajay Sutherland @emmajays.bsky.social · Dec 20

Curious about artificial deamidation? Check out our updated preprint! tinyurl.com/ms6fz3sn
Now with PBS as a 6th buffer + new K562 data + N-terminal Q -> pyro-Glu investigations.

Take home message: Zwitterionic buffers like HEPES minimize unwanted artifacts!

@riley-research.bsky.social

1 2

Reposted by Emmajay Sutherland

Science News @scinews.bsky.social · Dec 19

Just let me be a scientist:
The experienced, highly qualified postdoc is a valuable resource.

PDF download
www.embopress.org/doi/epdf/10....

4 17 83

Reposted by Emmajay Sutherland

Bluesky @bsky.app · Dec 3

Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪

Altmetric @altmetric.com · Dec 3

There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research.

A Place of Joy.

‘A place of joy’: why scientists are joining the rush to Bluesky
Researchers say the social-media platform — an alternative to X — offers more control over the content they see and the people they engage with.: https://www.nature.com/articles/d41586-024-03784-6

460 5.1K 30K

Reposted by Emmajay Sutherland

Riley Research Group @riley-research.bsky.social · Dec 2

Check out this UW highlight of RRG member @jacobrussell02.bsky.social and his path to graduate school as a first-generation student! Way to go, Jacob!

artsci.washington.edu/news/firstge...

We are First-Generation: College of Arts & Sciences Students and Alumni | UW College of Arts & Sciences

In the College of Arts & Sciences, we are proud to celebrate our first-generation community through a collection of stories! We honor our students and alumni, and their many contributions to our unive...

artsci.washington.edu

5 10

Reposted by Emmajay Sutherland

Johanna Joyce @johannajoyce.bsky.social · Nov 25

Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️

So how can we ever achieve #gender #equality?

We discuss various strategies in this #Cell Commentary

#WomeninSTEM

www.cell.com/cell/fulltex...
🧵 1/

35 600 1.2K

Reposted by Emmajay Sutherland

Verena Resch | 🧪🖥️ @verenaresch.bsky.social · Nov 25

I sometimes forget how flexible proteins are. It becomes really apparent when you use NMR states for an animation. That poor cofactor is getting pushed around a lot 😅

#sciart #blender3d #biocatalysis

13 83 480

Reposted by Emmajay Sutherland

Riley Research Group @riley-research.bsky.social · Nov 23

We updated some conferences of interest on the Useful Links page on our website:

www.riley-research.com/useful-links

We have yet to really advertise it, but it is a complication of resources we frequent for #TeamMassSpec, #glycotime, conferences, and more.

Hopefully others can find it useful too!

Riley Research Group at UW - Useful Links

Riley Research Group GitHub University of Washington's Proteomics Resource (UWPR) Human Glycoproteomics Initiative (HGI) via HUPO News in Proteomics Research blog by Dr. Ben Orsburn Inclusion in Chemi...

www.riley-research.com

1 1 9