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Endocrine-Related Cancer @endocancer.bsky.social · 9d

New research by Di Sun et al. investigates the long-term efficacy of anlotinib in patients with progressive RAIR-DTC and explores the predictive potential of PET/CT parameters.

🔗 Subscribers of Endocrine-Related Cancer can read the full article: doi.org/10.1530/ERC-25-0027

$NEW RESEARCH: Anlotinib in progressive RAI-refractory differentiated thyroid cancer: long-term results and PET/CT prognostic markers in Endocrine-Related Cancer. By Di Sun et al. Published by Bioscientifica. Society for Endocrinology.$

Endocrine-Related Cancer @endocancer.bsky.social · 13d

New retrospective cohort study by Branislav Klimacek et al. explores the non-operative management of initially asymptomatic patients diagnosed with small intestine neuroendocrine tumors, raising questions about current guidelines.

Read the full study here #OpenAccess: doi.org/10.1530/ERC-25-0205

Locoregional progression and surgical indications in stage IV asymptomatic SI-NETs in Endocrine-Related Cancer. By Branislav Klimácek et al.
Figure 2. Kaplan−Meier estimates of time to symptom onset in initially asymptomatic patients. A full color version of this figure is available at https://doi.org/10.1530/ERC-25-0205. Citation: Endocrine-Related Cancer 32, 8; 10.1530/ERC-25-0205
Published by Bioscientifica. Society for Endocrinology.

Endocrine-Related Cancer @endocancer.bsky.social · 15d

Be part of the global #neuroendocrinecancer research conversation in Boston, November 17-19.

The NETRF (@netrf.org) Annual Research Symposium brings together expert researchers to share leading-edge science and learn from each other.

Register now: bit.ly/4nQ9goU

#NETresearch #cancerresearch

Register Now! 2025 Margie & Robert E. Petersen. Neuroendocrine Tumor Research Symposium. Breakthroughs today, cures tomorrow.
Location: Boston, Massachusetts. Date: November 17-19.

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Reposted by Endocrine-Related Cancer

OncLive @onclive.bsky.social · 21d

Neoadjuvant Palbociclib Plus Endocrine Therapy Does Not Improve PEPI Scores in Resectable HR+ Breast Cancer
#BreastCancer #BCSM @endocancer.bsky.social
www.onclive.com/view/neoadju...

Neoadjuvant Palbociclib Plus Endocrine Therapy Does Not Improve PEPI Scores in Resectable HR+ Breast Cancer | OncLive

Neoadjuvant palbociclib plus endocrine therapy did not improved PEPI scores in operable hormone receptor–positive breast cancer.

www.onclive.com

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Reposted by Endocrine-Related Cancer

Neuroendocrine Tumor Research Foundation @netrf.org · 22d

Explore the latest in #pheochromocytoma & #paraganglioma research with Endocrine-Related Cancer’s (@endocancer.bsky.social) special collection, featuring recent advances in genetics, metabolomics, nuclear medicine & more.
Explore the collection: erc.bioscientifica.com/page/PPGL

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Endocrine-Related Cancer @endocancer.bsky.social · 22d

🔬 Discovery of a novel sodium iodide symporter regulatory pathway in breast cancer cells.

Vikki L Poole et al. opens new therapeutic avenues in #BreastCancer by mapping sodium iodide symporter regulation & pinpointing targets to boost radioiodide avidity.

Read #OpenAccess: doi.org/10.1530/ERC-...

New Research: Targeting Src tyrosine kinase to enhance radioiodide uptake in breast cancer in Endocrine-Related Cancer. By Vikki L Poole et al. Published by Bioscientifica. Society for Endocrinology.
Figure 1. Phosphorylated PBF represses RAIU in breast cancer cells. (A) Left – schematic of the interaction between NIS and PBF proteins tagged at the C-terminus with the NanoLuc luciferase subunits LgBiT and SmBiT, respectively. In close proximity, LgBiT and SmBiT form a functional enzyme that uses the substrate furimazine to produce a high-intensity, luminescent signal. Created using Alphafold (59, 60) and BioRender. Right – NanoBiT analysis of NIS:PBF interaction in MCF-7 cells, with bar graph showing results at 20 min post-addition of Nano-Glo live cell assay substrate. (B) Co-immunoprecipitation assay showing PBF-HA and NIS-MYC interaction in MCF-7 breast cancer cells. (C) Schematic of PBF highlighting the overlapping phosphorylation site and endocytosis motif at the C-terminus, and the PBF-Y174A and E170_N172delinsAAA (PBF-EEN MUT) mutants. (D) Western blot showing the phosphorylation status of PBF-Y174A and PBF-EEN MUT compared with PBF-WT in MCF-7 cells. (E) Immunofluorescent images showing PBF-WT, PBF-Y174A and PBF-EEN MUT localisation in MCF-7 cells. (F) Immunofluorescent images showing subcellular localisation following the co-transfection of NIS-MYC (green) with VO, PBF-WT, PBF-Y174A or PBF-EEN MUT (red) in MCF-7 cells. Co-localisation is seen in yellow. (G) The effect of PBF and phosphomutants (Y174A/EEN-MUT) on RAIU in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. (H) The effect of PBF and phosphomutants (Y174A/EEN-MUT) on RAIU in MCF-7 cells treated with ATRA and dexamethasone. VO = vector only control. Bars = 10 μm. n = 3 for all experiments. Error bars = SEM. Significance shown compared with VO unless otherwise shown...Endocrine-Related Cancer 32, 8; 10.1530/ERC-24-0312

Endocrine-Related Cancer @endocancer.bsky.social · 29d

New research by Exequiel Gonzalo Alonso et al. uncovers a protumor role for HO-1 in thyroid cancer by enhancing proliferation, migration & cell cycle progression. 🔎

🎯Could HO-1 be a therapeutic target?

Subscribers can read the research: doi.org/10.1530/ERC-25-0177

#ThyroidCancer #CancerResearch

New Research: Heme-oxygenase-1: a key player in thyroid carcinoma development in Endocrine-Related Cancer. By Exequiel Gonzalo Alonso et al.

Graphical Abstract.

Published by Bioscientifica. Society for Endocrinology.

Endocrine-Related Cancer @endocancer.bsky.social · Sep 5

🧠Contribute to Endocrine-Related Cancer's new Special Collection on pituitary tumours!

We welcome basic, translational & clinical studies that advance understanding & showcase innovations in the field.

📩Submit your proposal to: [email protected]
🌐More info: bit.ly/4mUXslc

Special Collection: Pituitary Tumours: Scientific Discoveries, Clinical Advances and Contested Paradigms.
Endocrine-Related Cancer.
Collection Editors:
Dr. Sunita M. C. De Sousa, MD, PhD
Dr. Frederic Castinetti, MD, PhD
Dr. Henriett Butz, MD, PhD
Dr. Adrian F. Daly, MD, PhD

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Endocrine-Related Cancer @endocancer.bsky.social · Sep 3

🎯Targeting RET in medullary thyroid cancer has played a key role in therapeutic strategies in the past decade.

A new review by Kate Newbold and Leslie Cheng explores targeted and selective RET therapies, and highlights the challenge of resistance.

🔗 doi.org/10.1530/ERC-24-0291

Targeting RET in medullary thyroid cancer in Endocrine-Related Cancer. By Kate Newbold and Leslie Cheng.

This paper forms part of the themed collection RET@Thirty: Three Decades of Remarkable Progress. The Guest Editors for this collection were Tom Kurzawinski, Neil McDonald and Kate Newbold.

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Endocrine-Related Cancer @endocancer.bsky.social · Aug 29

🌱Endocrine-Related Cancer is officially on LinkedIn!

Follow our new profile to stay up to date with the latest articles, special collections and updates from the journal.

🌐 linkedin.com/company/endocrine-related-cancer/

#MedSky #CancerResearch #EndocrineOncology #HormoneCancers

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Endocrine-Related Cancer @endocancer.bsky.social · Aug 26

✨ Systems biology approaches are reshaping our understanding of cancer.

Latest review by Michael V Orman et al. (@cupharmacology.bsky.social‬) highlights the successes & potential of these approaches in bettering our understanding of prostate cancer.

👉 #OpenAccess - doi.org/10.1530/ERC-25-0067

Endocrine-Related Cancer. Themed Collection: Systems Biology Approaches in Hormone Dependent Cancer Research.

New Review: Systems biology successes and areas for opportunity in prostate cancer in Endocrine-Related Cancer. By Michael V Orman et al.

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Endocrine-Related Cancer @endocancer.bsky.social · Aug 20

🌟We are delighted to announce that Prof. Alfred Lam, Professor of Pathology at Griffith University, has joined Endocrine-Related Cancer's editorial board as an Associate Editor.

👉 Explore his recent research article on the rising incidence of thyroid cancer: doi.org/10.1530/ERC-24-0326

Endocrine-Related Cancer. New Associate Editor. Professor Alfred Lam. Professor of Pathology, Griffith University, Australia.

Latest Research: Rising incidence of follicular thyroid carcinoma and oncocytic carcinoma of the thyroid. By Steven Weller, Cordia Chu, and Alfred King-yin Lam

Endocrine-Related Cancer @endocancer.bsky.social · Aug 18

Sponsored by @netrf.org, this $100,000 grant is designed to help an early-career, basic or clinical scientist conduct novel and innovative #NETs research.

Learn more: mierf.org/to-apply/

#neuroendocrinecancer #earlycareerresearcher

Endocrine-Related Cancer @endocancer.bsky.social · Aug 12

🎯Could DNA-PKcs be a potential target for differentiated thyroid cancer therapy?

Recent preclinical research by Shu-Fu Lin et al. reveals that M3814, a DNA-PKcs inhibitor, has significant potential in treating DTC.

🔗Explore the results: doi.org/10.1530/ERC-25-0031

New Research: DNA-PKcs inhibition as a therapeutic approach for differentiated thyroid cancer in Endocrine-Related Cancer. By Shu-Fu Lin et al.

Society for Endocrinology. Published by bioscientifica.

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Endocrine-Related Cancer @endocancer.bsky.social · Aug 7

How do treatments for neuroendocrine neoplasms impact quality of life?

A new review explores the impact of existing therapies such as somatostatin analogs, radioligand therapy, multikinase inhibitors & chemotherapy on quality of life in #NEN survivors.

📖 Read more: doi.org/10.1530/ERC-24-0303

New Review in Emerging Leaders 2025 Special Collection.
Impact of treatment on quality of life in neuroendocrine neoplasm survivors in Endocrine-Related Cancer. By Roberta Modica et al.
Endocrine-Related Cancer.

Endocrine-Related Cancer @endocancer.bsky.social · Jul 29

✨We are thrilled to welcome Dr. Karel Pacak as the incoming Editor-in-Chief of Endocrine-Related Cancer!

Dr. Pacak's term begins on 1st January 2026.

We are excited for this next chapter, driven by his expertise and vision 🚀

Endocrine-Related Cancer. Incoming Editor-in-Chief, Dr Karel Pacak.

"It is a great honor to assume the role of Editor-in-Chief of Endocrine-Related Cancer, a journal fully committed to raising awareness of endocrine cancers among healthcare providers by supporting excellence in basic and clinical research, high-quality studies, and evidence-based guidelines."

Published by Bioscientifica. Society for Endocrinology.

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Reposted by Endocrine-Related Cancer

Deborah Marsh @djmarsh24.bsky.social · Jul 22

The special collection in @endocancer.bsky.social - "From Discovery Science to the Clinic - Heritable Endocrine Cancers and Related Disorders" is open & calling for contributions. Edited by myself, Lois Mulligan & Joanne Ngeow in memory of Prof Charis Eng erc.bioscientifica.com/page/heritab... 🧪

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Endocrine-Related Cancer @endocancer.bsky.social · Jul 21

🧪New research by Jinheng Xiao et al. explores the distinct metabolic profiles of parathyroid carcinoma and parathyroid adenoma, identifying promising biomarkers for preoperative diagnosis of parathyroid carcinoma.

Read the full article #OpenAccess: doi.org/10.1530/ERC-24-0192

Endocrine-Related Cancer. New Open-Access Research: Plasma metabolomics for the preoperative diagnosis of parathyroid carcinoma. By Jinheng Xiao et al.

Published by Bioscientifica. Society for Endocrinology.

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Endocrine-Related Cancer @endocancer.bsky.social · Jul 12

Attending #ENDO2025? Come and visit the Bioscientifica booth, 803, to learn more about publishing in Endocrine-Related Cancer and pick up a booklet of recently published research 🤩🙌

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Reposted by Endocrine-Related Cancer

Society for Endocrinology @socendocrinology.bsky.social · Jul 4

Have you read the summer issue of The #Endocrinologist yet? 📰

Here are our editorial board’s picks of the ‘hot’ papers from the Society's journals and beyond. @joendocrinology.bsky.social @endocancer.bsky.social @natmetabolism.nature.com

Dive into the latest hot topics here 👉 bit.ly/3TTIn6f

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Endocrine-Related Cancer @endocancer.bsky.social · Jul 3

🧬New research by Mina Sattari et al. identifies 85 metastatic castration-resistant prostate cancer-associated genes, spotlighting TMEM18 as a promising prognostic biomarker in early prostate cancer.

👉 Explore the full article #OpenAccess: doi.org/10.1530/ERC-25-0070

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Reposted by Endocrine-Related Cancer

Deborah Marsh @djmarsh24.bsky.social · Jul 1

So happy to see @endocancer.bsky.social has newly joined Bluesky! Of all the editorial boards I've been on, this one is a highlight for dedicated academics creating a platform for strong research in this field. Q1 in the recent journal citation reports. Great home for endocrine cancer research 🧪

Endocrine-Related Cancer @endocancer.bsky.social · Jun 27

👋We are thrilled to join the @bsky.app community!

We spotlight novel research on endocrine neoplasias & hormone-dependent cancers.

Follow us for the latest articles, themed collections & developments in endocrine oncology.

🧬Explore: erc.bioscientifica.com

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Endocrine-Related Cancer @endocancer.bsky.social · Jun 27

👋We are thrilled to join the @bsky.app community!

We spotlight novel research on endocrine neoplasias & hormone-dependent cancers.

Follow us for the latest articles, themed collections & developments in endocrine oncology.

🧬Explore: erc.bioscientifica.com

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