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Fabian Theis @fabiantheis.bsky.social · 10d

🚀 Excited to share scPortrait! Led by Sophia Mädler & Niklas Schmacke w/ the Mann lab — a new @scverse tool for standardized single-cell image data. Enables ML-ready extraction, >1B cell processing, cross-omics, & cancer macrophage insights.
🔗 www.biorxiv.org/content/10.1...

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Fabian Theis @fabiantheis.bsky.social · 20d

not sure about competition only. think in current times EU needs sovereign AI for quite some fields right ..

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Fabian Theis @fabiantheis.bsky.social · 21d

Excited to speak today at the EC’s R&I Community event on RAISE – Building the Resource for AI Science in Europe.

We’ll discuss how pooling compute, data, talent & funding can supercharge AI-driven discovery across life sciences & health.

👉 stream: research-innovation-community.ec.europa.eu

The research and innovation community platform

The research and innovation community platform is a unique space bringing together researchers from the EU and beyond. Take part in events, access exclusive content, and widen your network.

research-innovation-community.ec.europa.eu

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Fabian Theis @fabiantheis.bsky.social · 27d

2nd day of our DLD Baiosphere conference starting out w aim to ‘put on some fairy dust’ (Yossi Vardi’s words) - w supermotivating Bohemian Rhapsody flashmob vid, watch it will make your day ☺️ youtu.be/jO2R_35HhiY

¡¡El Flashmob Bohemian Rhapsody más INCREÍBLE que jamás verás!!😍

youtu.be

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Fabian Theis @fabiantheis.bsky.social · 28d

Excited that our DLD Baiosphere conference on AI is starting now - with major political presence from Bavaria & great talks/panels from science and industry! MP Söder with strong commitment on academic freedom & local strength in AI to attract talents.

🚀https://dld-conference.com

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Fabian Theis @fabiantheis.bsky.social · Sep 8

New paper in @ScienceMagazine with Schoof & Porse labs: We chart early human hematopoiesis using single-cell proteomics, and amongst others developed a dynamic model linking RNA to protein levels, explaining more proteomic variation.

📄 www.science.org/doi/10.1126/...

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Fabian Theis @fabiantheis.bsky.social · Sep 3

Back from the SolvAI Retreat 2025 in Nice — amazing discussions on AI in science. Key themes: LMs alone won’t get us to scientific discovery, what makes a theory, and how AI can help us build them. Thanks to Eric Xing & Yann LeCun for organizing!

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Reposted by Fabian Theis

Bo Porse @porsebo.bsky.social · Aug 22

So excited to see it out in @science.org. See details below in the 🧵 from stellar former PhD student @bfurtwa.bsky.social.
Many thanks to all involved, especially Blueskyless Nil Uresin and Sabrina Richer and my co-PIs @fabiantheis.bsky.social and @erwinschoof.bsky.social

Benjamin Furtwängler @bfurtwa.bsky.social · Aug 22

We’re excited to present this integrative analysis of single-cell proteomics and transcriptomics of the human HSPC hierarchy. Now published in @science.org together with @fabiantheis.bsky.social, @erwinschoof.bsky.social, @porsebo.bsky.social.
www.science.org/doi/10.1126/...
🧵

Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics

Single-cell transcriptomics (scRNA-seq) has facilitated the characterization of cell state heterogeneity and recapitulation of differentiation trajectories. However, the exclusive use of mRNA measurem...

www.science.org

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Fabian Theis @fabiantheis.bsky.social · Jul 31

🚀 NSF just announced a $100M investment in National AI Research Institutes, with medicine & health applications listed first among priority areas, highlighting how biomedical impact continues to lead innovation and real-world benefit! www.nsf.gov/news/nsf-ann... 👩⚕️🔬 #AI #Health

NSF announces $100 million investment in National Artificial Intelligence Research Institutes awards to secure American leadership in AI

The investment will accelerate open innovation, empower an AI-ready workforce and strengthen U.S. global competitiveness...

www.nsf.gov

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Fabian Theis @fabiantheis.bsky.social · Jul 30

🚀 Exciting opportunity for scientists in the Bavarian AI ecosystem @bAIosphere!
Host your funded retreat or workshop at the beautiful, remote Speinshart Scientific Center for AI & SuperTech🤖.
👉 baiosphere.org/baiosphere-s...
👉 www.speinshart.ai
#AI #Bavaria #ScienceCommunity

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Fabian Theis @fabiantheis.bsky.social · Jul 28

Great to host Eric Xing, President & University Professor at MBZUAI, together with Dekyi Liang, Chief of Staff, at our Helmholtz Computational Health Center last Friday 🤖. Inspiring talk on “AI-driven Digital Organism” and engaging discussions with colleagues & PIs 🧬.

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Fabian Theis @fabiantheis.bsky.social · Jul 25

thanks Rob - also for staying until end of conference :). enjoyed the discussions a lot!

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Fabian Theis @fabiantheis.bsky.social · Jul 25

Very honored to receive the 2025 ISCB Innovator Award at #ISMBECCB2025 and present our lab’s journey—from mapping cells to modeling their future.

Thanks to my amazing team and collaborators—this is our award! 🙌

📽️ Keynote: Atlases, AI & virtual cells
📝 doi.org/10.1093/bioi...

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Reposted by Fabian Theis

Helmholtz Munich @helmholtzmunich.bsky.social · Jul 14

Three #ERC Proof of Concept Grants for #HelmholtzMunich 🚀

Projects by Marcus Conrad, Fabian Theis & André C. Stiel target cancer, AI-guided drug delivery & chip-based diagnostics.

👉 t1p.de/hz9x3

@erc.europa.eu
@fabiantheis.bsky.social

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Fabian Theis @fabiantheis.bsky.social · Jul 23

Laura Martens doing great job at presenting our work on deconvolution of spatial ATAC data at #ISMBECCB2025 at Liverpool - essentially: transcriptomic methods work here, too. academic.oup.com/bioinformati...

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Fabian Theis @fabiantheis.bsky.social · Jul 15

Interesting: www.nature.com/articles/d41... - low quality papers linking some seemingly random phenotypes eg in UKBiobank, "flooding" the literature. Exploring all possible combinatorial possibilities of phenotype combinations sounds like a science business model now...

Low-quality papers based on public health data are flooding the scientific literature

The appearance of thousands of formulaic biomedical studies has been linked to the rise of text-generating AI tools.

www.nature.com

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Fabian Theis @fabiantheis.bsky.social · Jul 10

Helmholtz Computational Health Center summer party! 🌞🎉 great people, great energy, and a reminder that science thrives with community! #TeamScience

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Fabian Theis @fabiantheis.bsky.social · Jul 9

This cancer organoid-based reference map will enable virtual cell modeling, supporting prediction of drug effects, resistance development, and identification of potential treatment targets. Looking forward to building powerful AI models on this to transform cancer therapy! #CancerAI #Plasticity

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Fabian Theis @fabiantheis.bsky.social · Jul 9

Thrilled to collaborate with Mathew Garnett @Sanger and Parse Biosciences on the new Cancer Plasticity Atlas – a hugely exciting single cell genomics resource to decode tumor adaptation. 🔗 helmholtz-munich.de/en/newsroom/news-all/artikel/cancer-plasticity-atlas-to-improve-cancer-therapies

Helmholtz Munich

Helmholtz Munich, is a member of the Helmholtz Association of German Research Centres

helmholtz-munich.de

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Reposted by Fabian Theis

Stegle Lab @steglelab.bsky.social · Jul 4

Join us for a series of presentations from leading data science experts, including @francescafinotello.bsky.social, @dominicgrun.bsky.social, Johanna Klughammer, Malte Lücken, @fabiantheis.bsky.social and @jwrth.genomic.social.ap.brid.gy.

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Reposted by Fabian Theis

Alex Kalinin @alxndrkalinin.bsky.social · Jul 8

🔬API-first feature extraction for image-based profiling workflows

If you need to obtain interpretable features from your segmented microscopy images, but want to do it in a fully automated way, we know the struggle.

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Fabian Theis @fabiantheis.bsky.social · Jul 4

🚀 Ewa Szczurek kicking off the AI for Health Symposium 2025 at Helmholtz Munich today! Excited to listen to local and international experts on how generative AI is transforming molecule discovery and health. 🌟 events.hifis.net/event/2015 #AIforHealth #GenAI #Helmholtz

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Reposted by Fabian Theis

Helmholtz Munich @helmholtzmunich.bsky.social · Jul 3

🏆 Helmholtz Munich wins the #m4Award2025 for SYNTRA, an #AI-powered #RNA delivery project. The pre-seed prize supports spin-offs in Bavaria. SYNTRA aims to safely deliver RNA to target cells, enabling new therapies for genetic & other diseases.

👉 t1p.de/6fyup

@fabiantheis.bsky.social
#BioM

m4 Award 2025 Goes to Helmholtz Munich for RNA Therapy Innovation

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Fabian Theis @fabiantheis.bsky.social · Jul 3

🚀 Yesterday marked kickoff of the *M1 Munich Medicine Alliance* – uniting LMU, TUM, and Helmholtz Munich to build Germany’s leading medical innovation hub. Major step twds translational excellence, AI-powered health, & better patient outcomes. Great!
🔗 m1.bayern

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Fabian Theis @fabiantheis.bsky.social · Jul 3

New OpenProblems paper out! 📝

Led by Malte Lücken with Smita Krishnaswamy, we present openproblems.bio – a community-driven platform benchmarking single-cell analysis methods.

Excited about transparent, evolving best practices for the field!

🔗 www.nature.com/articles/s41...

Defining and benchmarking open problems in single-cell analysis - Nature Biotechnology

Nature Biotechnology - Defining and benchmarking open problems in single-cell analysis

www.nature.com

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