Faria Tryps Lab
@fariatrypslab.bsky.social
The Faria Lab is based at University of York and studies nuclear architecture, genome organisation and biomolecular condensates in the context of gene expression regulation in trypanosomatids
Merci Philippe 😊
February 4, 2026 at 1:17 PM
Merci Philippe 😊
5/5 PS: More to come on the ever-growing ‘ESB molecular consortium’ and a new layer of post-transcriptional regulation through specialised RNA decay. Stay tuned for an update on our preprint!
February 4, 2026 at 11:25 AM
5/5 PS: More to come on the ever-growing ‘ESB molecular consortium’ and a new layer of post-transcriptional regulation through specialised RNA decay. Stay tuned for an update on our preprint!
4/5 Science is better together. We hope these insights into ESBX open new doors for understanding immune evasion and fundamental principles of gene regulation.
Full paper here: doi.org/10.1073/pnas...
Full paper here: doi.org/10.1073/pnas...
A factor integrating transcription and repression of surface antigen genes in African trypanosomes | PNAS
Antigenic variation in Trypanosoma brucei (T. brucei) requires monoallelic expression
of one variant surface glycoprotein (VSG) from one of the sub...
doi.org
February 4, 2026 at 11:25 AM
4/5 Science is better together. We hope these insights into ESBX open new doors for understanding immune evasion and fundamental principles of gene regulation.
Full paper here: doi.org/10.1073/pnas...
Full paper here: doi.org/10.1073/pnas...
3/5 After the loss of Prof. Gloria Rudenko @imperialcollegeldn.bsky.social the UK scientific community stepped up. Guided by Prof. Keith Gull, multiple labs collaborated to cross the finish line. Pleasure to collaborate with Sunter, @zephyris-science.bsky.social & @tiengwe-tryplab.bsky.social Labs
February 4, 2026 at 11:25 AM
3/5 After the loss of Prof. Gloria Rudenko @imperialcollegeldn.bsky.social the UK scientific community stepped up. Guided by Prof. Keith Gull, multiple labs collaborated to cross the finish line. Pleasure to collaborate with Sunter, @zephyris-science.bsky.social & @tiengwe-tryplab.bsky.social Labs
2/5 Using trypanosomes as a model, we found that ESBX coordinates activation and repression of surface antigen genes. This "monoallelic expression" is a fundamental mystery in biology.
February 4, 2026 at 11:25 AM
2/5 Using trypanosomes as a model, we found that ESBX coordinates activation and repression of surface antigen genes. This "monoallelic expression" is a fundamental mystery in biology.
Jobs - The University of York
jobs.york.ac.uk
January 28, 2026 at 12:32 PM
Jobs - The University of York
jobs.york.ac.uk
January 28, 2026 at 12:32 PM
Great collaborators at University of Warwick and @ipmontevideo.bsky.social @carlos-robello.bsky.social Huge thanks to our funders BBSRC
January 28, 2026 at 12:32 PM
Great collaborators at University of Warwick and @ipmontevideo.bsky.social @carlos-robello.bsky.social Huge thanks to our funders BBSRC
So excited to have Alex joining us!!
November 10, 2025 at 6:19 PM
So excited to have Alex joining us!!