Lightnews — Scholar-powered news

Farshid Guilak @farsh-g.bsky.social · Aug 5

Thanks for all your participation in the session!

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Farshid Guilak @farsh-g.bsky.social · Jul 21

Thanks so much @ardemp.bskyverified.social!

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Reposted by Farshid Guilak

Ardem Patapoutian @ardemp.bskyverified.social · Jul 21

Exciting new study on the role of PIEZOs in Chondrocytes! Relevance to arthritis and pain. From: @farsh-g.bsky.social & @kelseyhcollins.bsky.social
arthritis-research.biomedcentral.com/articles/10....

Chondrocyte-specific knockout of Piezo1 and Piezo2 protects against post-traumatic osteoarthritis structural damage and pain in mice - Arthritis Research & Therapy

Background Osteoarthritis (OA) is a debilitating joint disease characterized by cartilage degeneration, synovial inflammation, and bone remodeling, with limited therapeutic options targeting the under...

arthritis-research.biomedcentral.com

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Farshid Guilak @farsh-g.bsky.social · Jun 23

Congrats to Amanda Cimino and team on her latest paper in @JCRnEDITORS - she developed new synthetic chronogenetic gene circuits that allow controlled drug delivery at precise times day using various elements of the circadian clock! doi.org/10.1016/j.jc...

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Farshid Guilak @farsh-g.bsky.social · Jun 11

Huge congrats to Dr. Amanda Cimino for an outstanding presentation and defense - her committee said it was time for a "PhD+" degree. Amazing work!

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Farshid Guilak @farsh-g.bsky.social · Jun 3

Chronotherapy in Rheumatoid Arthritis Treatment: Tantalizing but Understudied
www.medscape.com/viewarticle/...

Chronotherapy in RA Treatment: Tantalizing but Understudied

Research is evaluating chronotherapy to target drugs to reduce morning stiffness and flares in rheumatoid arthritis, but it has a long way to go before it reaches the clinic.

www.medscape.com

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Reposted by Farshid Guilak

Stand Up for Science! @standupforscience.bsky.social · May 22

We don’t always know what questions will change the world.

But public science has a way of answering them anyway.

Federal science funding isn’t just lines in a budget. It’s a vote for progress, for possibility.

www.nytimes.com/2025/05/16/s...

9 Federally Funded Scientific Breakthroughs That Changed Everything

www.nytimes.com

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Farshid Guilak @farsh-g.bsky.social · May 22

Most studies of cartilage mechanobiology study the upregulation of chondrocyte gene expression and biosynthesis with mechanical loading. Check out our recent paper where Daniel Palmer studied the down-regulated "mechanome" with Piezo1 or TRPV4 activation. www.tandfonline.com/doi/full/10....

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Reposted by Farshid Guilak

FASEB @faseborg.bsky.social · May 22

Your research on Ion Channel Regulation might be the next watershed discovery! Join FASEB for the latest findings at #ICRSRC with keynote speaker @farsh-g.bsky.social
and organizers @roseedixon.bsky.social and Jonathan Silva. Submit your abstract by June 8 and save your space now! buff.ly/A3wmAbp

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Farshid Guilak @farsh-g.bsky.social · May 20

Congrats to Amanda Cimino for her latest paper creating a chronogenetic gene circuit that automatically delivers anti-inflammatory biologic drugs in response to inflammation or circadian signal! jbioleng.biomedcentral.com/articles/10....

Farshid Guilak @farsh-g.bsky.social · May 13

Lots of celebrations this month in the Guilak Lab! Congrats to Xinyi Melissa Li and Katelyn Lipa for passing their qualifying exams with flying colors!

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Reposted by Farshid Guilak

Satanik Mukherjee @satanikm.bsky.social · May 8

🚨 Big updates!
✅ Successfully defended my PhD thesis:
“Multiscale Modeling of Chondrocyte Mechanobiology: Insights into Degeneration and Regeneration”
✅ Joined the lab of @farsh-g.bsky.social at WashU St Louis as a Rita Levi-Montalcini Postdoc Fellow in regenerative medicine!
Grateful & excited !

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Reposted by Farshid Guilak

American Institute for Medical & Biological Engineering (AIMBE) @aimbe-official.bsky.social · May 5

Please widely share these 3 new advocacy letter templates with your colleagues.

@lolauic.bsky.social @orssociety.bsky.social @bmes-cmbe.bsky.social @aapmhq.bsky.social @acadrad.bsky.social @ceschmidt2024.bsky.social @settonlab.bsky.social @tejaladesai.bsky.social @farsh-g.bsky.social

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Reposted by Farshid Guilak

Anne-Marie Malfait @jointsintheworld.bsky.social · May 2

Join us for our quarterly C-COMP journal club, featuring this exciting new paper by the team of @kelseyhcollins.bsky.social and @farsh-g.bsky.social Monday May 12th 10 am CST- ask us how to register!

www.science.org/doi/full/10....

Adipose-derived leptin and complement factor D mediate osteoarthritis severity and pain

Osteoarthritis and knee joint pain are driven by systemic leptin and complement factor D secreted by adipose tissue.

www.science.org

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Farshid Guilak @farsh-g.bsky.social · May 1

Congrats to Sophie Paradi on a fantastic Master's thesis and defense! Amazing work and collaboration with Erica Ely and many others in the Guilak Lab

Reposted by Farshid Guilak

FASEB @faseborg.bsky.social · Apr 28

Ion channel research can have major consequences for cancer and cardiovascular disease treatments. Join FASEB at #ICRSRC for the latest findings with keynote speaker @farsh-g.bsky.social and organizer @roseedixon.bsky.social. Check out the full program and save your space: buff.ly/d213NE1

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Farshid Guilak @farsh-g.bsky.social · Apr 25

Congrats ‪@kelseyhcollins.bsky.social‬ on another tour de force, shedding further light into the relationship between obesity and OA! The more we learn, the more complex it gets... Fantastic collaboration with the June lab and WashU Rheumatology!

Kelsey H. Collins @kelseyhcollins.bsky.social · Apr 25

Excited to share the latest chapter of our work on fat-joint interorgan crosstalk in knee OA, featuring the role of complement factor D secreted by fat in knee pain. Link here: bit.ly/42Og5hJ

Thanks to @farsh-g.bsky.social for all of your support - @thehopefulscie1.bsky.social and all coauthors!

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Farshid Guilak @farsh-g.bsky.social · Apr 24

put me in, coach...

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Farshid Guilak @farsh-g.bsky.social · Apr 24

Join us today for our AOC Thought Leaders Webinar: Managing the Research Enterprise — for anyone navigating the evolving landscape of academic orthopaedics.

April 24 | 4:00 PM ET
Register Here: lnkd.in/eTrzEem6

Joint the AOC at myaocconnect.com!

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Farshid Guilak @farsh-g.bsky.social · Apr 10

Congrats Dr. Jackie Garcia on an amazing dissertation on defense "Characterizing PIEZO1 Mechanotransduction in Articular Chondrocytes"!

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Farshid Guilak @farsh-g.bsky.social · Apr 7

Excited for our most recent publication mapping macrophage populations in the synovium with knee injury and obesity! Great work by @nharasymowicz.bsky.social and team!

Natalia Harasymowicz @nharasymowicz.bsky.social · Apr 7

Obesity has a distinct impact on the progression of OA. We showed significant loss of protective synovial lining macrophages in the synovium 3 days after joint injury, with a significant restoration in normal-weight but not in obese mice @farsh-g.bsky.social
ard.eular.org/article/S000...

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Farshid Guilak @farsh-g.bsky.social · Mar 24

Congrats Hope!

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Farshid Guilak @farsh-g.bsky.social · Mar 18

www.menshealth.com/health/a6375...

A Definitive Guide to Racquet Sports, From Tennis to Pickleball to Padel

There are so many racquet sports with varying levels of difficulty, benefits, and #vibes. Find the one that's right for you here.

www.menshealth.com

Reposted by Farshid Guilak

American Institute for Medical & Biological Engineering (AIMBE) @aimbe-official.bsky.social · Mar 11

The 3/14 deadline to finalize the FY2025 budget is fast approaching! ⌛

AIMBE has developed a new advocacy letter (<1 min to send) for the scientific community to urge Congress to support our federal science agencies, including NIH, NSF, FDA, ARPA-H, CDMRP, and more 👇

takeaction.io/aimbe/suppor...

Support Strong FY25 Funding for Biomedical Research by March 14

Use AIMBE's letter template below, edit as needed, or create your own message to your Members of Congress on issues that matter. Enter your contact information on the left, and your letter will be rou...

takeaction.io

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Farshid Guilak @farsh-g.bsky.social · Mar 7

Engineered stem cells automatically deliver arthritis drugs at prescribed times of day
apnews.com/press-releas...
www.nature.com/articles/s41...

Engineered stem cells automatically deliver arthritis drugs at prescribed times of day

“This technology has the potential to change a lot of lives.

apnews.com

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