Lightnews — Scholar-powered news

Reposted by Fabian Blombach

The Daum Lab @daumlab.bsky.social · 1d

We have an exciting PhD opportunity to study ribosome hibernation in archaea using cryo-electron microscopy, tomography, microfluidics, omics, and confocal imaging. @daumlab.bsky.social,
@lsiexeter.bsky.social
Apply via:
www.exeter.ac.uk/study/fundin...
Any questions, IM me.

4 5

Reposted by Fabian Blombach

Sonja-Verena Albers @archaellum.bsky.social · 23d

Happy to share that our story on the bacterial archaellum was published today in @natmicrobiol.nature.com
www.nature.com/articles/s41...

Congrats to the authors: @sshamphavi.bsky.social @loumollat.bsky.social @mariejoest.bsky.social Najwa Taib and @sgribaldo.bsky.social

7 58 120

Reposted by Fabian Blombach

Mukund Thattai @thattai.bsky.social · Aug 4

I set out to review the evolution of eukaryotic intracellular traffic, but along the way a new hypothesis came into focus: maybe the earliest membrane carriers were tubules, not coated vesicles!

New preprint: ecoevorxiv.org/repository/v...

Here’s the idea. 🧵

A schematic showing two models for the evolution of the eukaryotic cell plan starting from an archaeal ancestor. The "inside-out" and "outside-in" models both lead to an intermediate stage with internal and plasma membranes connected by tubules. The sequence continues through the formation of an endomembrane lumen, followed by the emergence of membrane contact sites and tubular carriers, and finally coated vesicles and stable compartments.

5 15 41

Reposted by Fabian Blombach

Sternberg Lab @sternberglab.bsky.social · Jul 24

1/16 New pre-print from the Sternberg Lab!
We uncover how temperate phages can use RNA-guided transcription factors to remodel the flagellar composition of their bacterial host and enhance their fitness.
Find the preprint and full story here: tinyurl.com/mshwjd77

3 35 71

Reposted by Fabian Blombach

Daniela Barillà @danielabarilla.bsky.social · Jul 22

And the story is published now!🍾
www.nature.com/articles/s41...

Open access link: rdcu.be/exnOc

Many years in the making, great collaboration with @archaellum.bsky.social & @tunglejic.bsky.social

Thanks @ukri.org BBSRC & @leverhulme.ac.uk for funding, reviewers & editor!! 🙏
#microsky #archaeasky

4 33 84

Reposted by Fabian Blombach

Miguel Gómez-Raya @miguelgrv.bsky.social · Jul 1

Elated to have our pre-print now published in @natcomms.nature.com #ArchaeaSky #Microbiology #MEvoSky
rdcu.be/euila
Our main results stay the same: S. islandicus follows a cell cycle akin to that of some eukaryotes, like the budding yeast, with cellular processes cycling similarly.
old🧵cited below👇

1 17 30

Reposted by Fabian Blombach

Dame lab at Leiden University @damelab.bsky.social · Jun 30

A must-read for histone afficionados: our new review on 'Histone-mediated chromatin organization in prokaryotes and viruses' www.cell.com/trends/bioch... @samuelschwab.bsky.social @vikramalva.bsky.social

Histone-mediated chromatin organization in prokaryotes and viruses

Histones are fundamental chromatin-organizing proteins in eukaryotes and archaea, where they assemble into (hyper)nucleosomes that wrap DNA. Recent studies have expanded the known repertoire of histon...

www.cell.com

16 42

Reposted by Fabian Blombach

Svetlana Dodonova @dodonova-sveta.bsky.social · May 26

We’ve uncovered Asgard chromatin structures formed by a Hodarchaeal histone : closed hypernucleosome conserved in archaea and an open form resembling the H3-H4 eukaryotic octasome. Fantastic work by @harshranawat.bsky.social!
www.biorxiv.org/content/10.1...
#Chromatin #Asgard #Archaea #cryoEM

13 100 240

Reposted by Fabian Blombach

Dina Grohmann @curiousdina.bsky.social · May 1

In this new publication, we took #archaea for a walk in the chemical garden 😉. The abiotic hydrogen produced in this setting can fuel M. jannaschii’s metabolism. Great interdisciplinary collaboration with the Orsi lab who initiated and led this study. More here www.nature.com/articles/s41...

Simulated early Earth geochemistry fuels a hydrogen-dependent primordial metabolism - Nature Ecology & Evolution

In an iron-sulfide chemical garden experiment that mimics the kind of hydrothermal vents that might have occurred in the early Archaean, mackinawite and greigite are precipitated and abiotic H2 is pro...

www.nature.com

10 28

Reposted by Fabian Blombach

Antoine Hocher @ahocher.bsky.social · Mar 22

The MIMIC lab is hiring a Postdoctoral Research Associate to join my team at @Cambridge_Uni!
Exploration and engineering DNA-mimicking proteins (wet-lab position.) 🧬
Details: www.jobs.cam.ac.uk/job/50652/
Please get in touch / circulate !

Research Associate (Fixed Term) - Job Opportunities - University of Cambridge

Research Associate (Fixed Term) in the Department of Genetics at the University of Cambridge.

www.jobs.cam.ac.uk

20 14

Reposted by Fabian Blombach

Malcolm White @mfwhite2.bsky.social · Mar 31

www.findaphd.com/phds/project...
A funded PhD studentship is available for a joint project between my lab and @andreashaag.bsky.social @uniofstandrews.bsky.social

Harnessing Bacterial Viruses to Combat Antibiotic-Resistant Infections at University of St Andrews on FindAPhD.com

PhD Project - Harnessing Bacterial Viruses to Combat Antibiotic-Resistant Infections at University of St Andrews, listed on FindAPhD.com

www.findaphd.com

12 5

Reposted by Fabian Blombach

Daniela Barillà @danielabarilla.bsky.social · Feb 9

New preprint from our lab!
Story started long ago that took many years in the making.

Great collaboration with @archaellum.bsky.social & @tunglejic.bsky.social groups.

Generously funded by BBSRC @ukri.org & @leverhulme.bsky.social

How do #archaea segregate their chromosome?
#microsky #archaeasky

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · Feb 9

Coupling chromosome organization to genome segregation in Archaea https://www.biorxiv.org/content/10.1101/2025.02.07.637068v1

1 18 44

Reposted by Fabian Blombach

Daniela Barillà @danielabarilla.bsky.social · Feb 6

📢 New round of PhD studentships.
Open to applicants worldwide.

📅 Deadline 14th March
www.findaphd.com/phds/project...

#microsky #archaeasky #chromosome 🧬🧬🧬
@steve-quinn-lab.bsky.social @georgerheath.bsky.social

Join us in beautiful York, UK!

Life pushed to extremes: probing the mechanisms of chromosome segregation in thermophilic Archaea at University of York on FindAPhD.com

PhD Project - Life pushed to extremes: probing the mechanisms of chromosome segregation in thermophilic Archaea at University of York, listed on FindAPhD.com

www.findaphd.com

13 12

Reposted by Fabian Blombach

Grainger Lab @graingerlab.bsky.social · Jan 21

If you're interested in chromosome biology (DNA folding, gene regulation, replication, polymer modelling and more) we're organising the below this autumn. It'd be great to see you there. Please share if you can. :-)

29 27

Fabian Blombach @fblombach.bsky.social · Jan 7

Structural biology focussed:
www.ucl.ac.uk/work-at-ucl/...

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

www.ucl.ac.uk

Fabian Blombach @fblombach.bsky.social · Jan 7

Molecular biology focussed:
www.ucl.ac.uk/work-at-ucl/...?
nPostingId=12427&nPostingTargetId=30932&id=Q1KFK026203F3VBQBLO8M8M07&LG=UK&languageSelect=UK&mask=ext

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

www.ucl.ac.uk

1

Fabian Blombach @fblombach.bsky.social · Jan 7

Functional genomics focussed:
www.ucl.ac.uk/work-at-ucl/...

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

www.ucl.ac.uk

1

Fabian Blombach @fblombach.bsky.social · Jan 7

Interested in the complexity of gene expression in Archaea? We have three open postdoc positions focussing on the coupling of transcription and translation using functional genomics, structural biology and molecular biology in Finn Werner's lab at UCL. Links below!

1 9 8