Dina Grohmann
@curiousdina.bsky.social
Curious scientist and fan of single molecules, RNA and Archaea
Reposted by Dina Grohmann
An archaeal genetic code with all TAG codons as pyrrolysine www.science.org/doi/abs/10.1... #jcampubs
An archaeal genetic code with all TAG codons as pyrrolysine
Multiple genetic codes developed during the evolution of eukaryotes and bacteria, yet no alternative genetic code is known for archaea. We used proteomics to confirm our prediction that certain archae...
www.science.org
November 21, 2025 at 4:20 PM
An archaeal genetic code with all TAG codons as pyrrolysine www.science.org/doi/abs/10.1... #jcampubs
I like to show the evolution of this classification to the students to highlight the fantastic bioinformatics work of Kira and Eugene and co-authors but also to illustrate the rapid development in the field ☺️.
November 7, 2025 at 2:25 PM
I like to show the evolution of this classification to the students to highlight the fantastic bioinformatics work of Kira and Eugene and co-authors but also to illustrate the rapid development in the field ☺️.
True!
Scientists feel that the pressure to publish is rising, but that the time and resources they have to do the necessary research are falling, according to a survey of 3,200 researchers
go.nature.com/4hNDvuN
go.nature.com/4hNDvuN
Pressure to publish is rising as research time shrinks, finds survey of scientists
Researchers feel that pressures to publish are increasing, but the time and resources available to do research are decreasing, according to a survey by Elsevier.
go.nature.com
November 7, 2025 at 2:19 PM
True!
Reposted by Dina Grohmann
Heute noch mal
November 2, 2025 at 10:43 AM
Heute noch mal
Reposted by Dina Grohmann
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
October 28, 2025 at 3:07 PM
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
How to become a "hot RNA" 🌡️? The answers were kindly provided by hyperthermophilic archaea: rRNA modifications are key! Check out this new publication presenting pan-modification profiling of the epitranscriptome. www.cell.com/cell/fulltex.... (1/3)
Pan-modification profiling facilitates a cross-evolutionary dissection of the thermoregulated ribosomal epitranscriptome
Pan-Mod-seq enables systematic, multi-modification mapping of rRNA across life. Applying
it to diverse organisms reveals that hyperthermophiles dynamically install stabilizing
modifications to support...
www.cell.com
October 27, 2025 at 1:19 PM
How to become a "hot RNA" 🌡️? The answers were kindly provided by hyperthermophilic archaea: rRNA modifications are key! Check out this new publication presenting pan-modification profiling of the epitranscriptome. www.cell.com/cell/fulltex.... (1/3)
Reposted by Dina Grohmann
We are hiring…position suitable for PhD student with interest in ribosomes, antibiotics and cryoEM…
www.uni-hamburg.de/en/stellenan...
www.uni-hamburg.de/en/stellenan...
Job advertisement
www.uni-hamburg.de
October 16, 2025 at 4:02 PM
We are hiring…position suitable for PhD student with interest in ribosomes, antibiotics and cryoEM…
www.uni-hamburg.de/en/stellenan...
www.uni-hamburg.de/en/stellenan...
Reposted by Dina Grohmann
ribosomologists take note 👇
archaeal ribosome hibernation factors aRDF, Dri, ...and now: Hib (see ALT)
#Archaea #ArchaeaSky
archaeal ribosome hibernation factors aRDF, Dri, ...and now: Hib (see ALT)
#Archaea #ArchaeaSky
October 12, 2025 at 7:13 PM
ribosomologists take note 👇
archaeal ribosome hibernation factors aRDF, Dri, ...and now: Hib (see ALT)
#Archaea #ArchaeaSky
archaeal ribosome hibernation factors aRDF, Dri, ...and now: Hib (see ALT)
#Archaea #ArchaeaSky
Reposted by Dina Grohmann
Are you interested in Biomolecular Condensates and looking for a PhD training? Check out the 12 (!) open PhD positions (also 1 on smFRET & condensates 🙃) in Dresden @rtg3120.bsky.social @tudresden.bsky.social starting April 2026. Apply latest by 24 Oct 2025 here: dresdencondensates.org/join-us/
Join Us – RTG 3120 Biomolecular Condensates
dresdencondensates.org
October 7, 2025 at 12:46 PM
Are you interested in Biomolecular Condensates and looking for a PhD training? Check out the 12 (!) open PhD positions (also 1 on smFRET & condensates 🙃) in Dresden @rtg3120.bsky.social @tudresden.bsky.social starting April 2026. Apply latest by 24 Oct 2025 here: dresdencondensates.org/join-us/
Reposted by Dina Grohmann
You can get MSAs directly from AlphaFold DB now (alphafold.ebi.ac.uk). I also missed the FoldSeek implementation, which lets you search for structurally similar proteins direktly.
This saves some clicking around. Neat!
This saves some clicking around. Neat!
October 7, 2025 at 2:54 PM
You can get MSAs directly from AlphaFold DB now (alphafold.ebi.ac.uk). I also missed the FoldSeek implementation, which lets you search for structurally similar proteins direktly.
This saves some clicking around. Neat!
This saves some clicking around. Neat!
Reposted by Dina Grohmann
Thank you Jane Goodall for EVERY SINGLE SENTENCE in this interview to remind us of what is important and to encourage us to never loose hope and to try to make a difference everyday of our life 🤝🫶!!!
Dr. Jane Goodall filmed an interview with Netflix in March 2025 that she understood would only be released after her death.
October 5, 2025 at 12:45 PM
Thank you Jane Goodall for EVERY SINGLE SENTENCE in this interview to remind us of what is important and to encourage us to never loose hope and to try to make a difference everyday of our life 🤝🫶!!!
Reposted by Dina Grohmann
"Jane" (2017), directed by Brett Morgen, with music by Philip Glass, and based on unseen footage discovered shortly before, is one of the most enchanting films I've ever seen. Goodbye Jane Goodall, and thank you.
www.youtube.com/watch?v=FRlU...
www.youtube.com/watch?v=FRlU...
Official Film Trailer: JANE | National Geographic
YouTube video by National Geographic
www.youtube.com
October 2, 2025 at 1:58 AM
"Jane" (2017), directed by Brett Morgen, with music by Philip Glass, and based on unseen footage discovered shortly before, is one of the most enchanting films I've ever seen. Goodbye Jane Goodall, and thank you.
www.youtube.com/watch?v=FRlU...
www.youtube.com/watch?v=FRlU...
Reposted by Dina Grohmann
Our story describing the Panoptes bacterial immune defense system is now finally peer-reviewed and published today! www.nature.com/articles/s41...
The Panoptes system uses decoy cyclic nucleotides to defend against phage - Nature
The Panoptes antiphage system defends bacteria by detecting phage-encoded counter-defences that sequester cyclic nucleotide signals, triggering membrane disruption and highlighting a broader strategy of sensing immune evasion through second-messenger surveillance.
www.nature.com
October 1, 2025 at 4:05 PM
Our story describing the Panoptes bacterial immune defense system is now finally peer-reviewed and published today! www.nature.com/articles/s41...
Reposted by Dina Grohmann
Become my colleague @oxfordbiochemistry.bsky.social !
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism
my.corehr.com/pls/uoxrecru...
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism
my.corehr.com/pls/uoxrecru...
Job Details
my.corehr.com
September 29, 2025 at 9:25 AM
Become my colleague @oxfordbiochemistry.bsky.social !
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism
my.corehr.com/pls/uoxrecru...
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism
my.corehr.com/pls/uoxrecru...
Reposted by Dina Grohmann
Biogenesis and function of archaeal lipoproteins.
This takes me back. The first papers I published from my new group were on lipoprotein biogenesis in Streptomyces with @proftracypalmer.bsky.social about 15y ago.
www.nature.com/articles/s41...
This takes me back. The first papers I published from my new group were on lipoprotein biogenesis in Streptomyces with @proftracypalmer.bsky.social about 15y ago.
www.nature.com/articles/s41...
Uncovering the prevalence, key biogenesis enzymes, and biological significance of archaeal lipoproteins - Nature Communications
Lipoproteins are major cell-surface components in archaea, but their functions and the lipidation mechanisms are unclear. Here, Hong et al. identify two proteins required for attachment of proteins to unique archaeal membrane lipids via thioether bonds, and demonstrate their importance in archaeal physiology.
www.nature.com
September 28, 2025 at 10:54 AM
Biogenesis and function of archaeal lipoproteins.
This takes me back. The first papers I published from my new group were on lipoprotein biogenesis in Streptomyces with @proftracypalmer.bsky.social about 15y ago.
www.nature.com/articles/s41...
This takes me back. The first papers I published from my new group were on lipoprotein biogenesis in Streptomyces with @proftracypalmer.bsky.social about 15y ago.
www.nature.com/articles/s41...
Reposted by Dina Grohmann
Find up to date links to the Farnung lab's cloning, experiment designer, and buffer preparation software tools here: www.farnunglab.com/tools
Services 3 — Farnung Lab
www.farnunglab.com
September 25, 2025 at 12:55 PM
Find up to date links to the Farnung lab's cloning, experiment designer, and buffer preparation software tools here: www.farnunglab.com/tools
Reposted by Dina Grohmann
Interested in removing particle-associated microbes from particles for eg flow cytometry, culturing, or other single-cell microbiology purposes? Led by graduating PhD stdnt Jordan Coelho:
Detergent-based separation of microbes from marine particles journals.asm.org/doi/10.1128/... #jcampubs 🌊
Detergent-based separation of microbes from marine particles journals.asm.org/doi/10.1128/... #jcampubs 🌊
September 25, 2025 at 4:29 PM
Interested in removing particle-associated microbes from particles for eg flow cytometry, culturing, or other single-cell microbiology purposes? Led by graduating PhD stdnt Jordan Coelho:
Detergent-based separation of microbes from marine particles journals.asm.org/doi/10.1128/... #jcampubs 🌊
Detergent-based separation of microbes from marine particles journals.asm.org/doi/10.1128/... #jcampubs 🌊
Reposted by Dina Grohmann
To maintain genome integrity, extreme organisms like archaea rely heavily on repair pathways.
This #FEMSmicroBlog explains how the halophile model organism Haloferax volcanii repairs DNA double strand breaks quickly and efficiently. #FascinatingMicrobes
This #FEMSmicroBlog explains how the halophile model organism Haloferax volcanii repairs DNA double strand breaks quickly and efficiently. #FascinatingMicrobes
#FEMSmicroBlog: Halophile archaea healing themselves
This #FEMSmicroBlog explains how the halophile model organism Haloferax volcanii repairs DNA double strand breaks quickly and efficiently. #FascinatingMicrobes
buff.ly
September 23, 2025 at 9:01 AM
To maintain genome integrity, extreme organisms like archaea rely heavily on repair pathways.
This #FEMSmicroBlog explains how the halophile model organism Haloferax volcanii repairs DNA double strand breaks quickly and efficiently. #FascinatingMicrobes
This #FEMSmicroBlog explains how the halophile model organism Haloferax volcanii repairs DNA double strand breaks quickly and efficiently. #FascinatingMicrobes
Reposted by Dina Grohmann
new Lai lab #miRNA paper alert!! happy to share Renfu Shang's mechanistic insights into the mysteries of miRNA cluster assistance. wonderful collab with Niko Popitsch and @ameressl.bsky.social
🧵 later, but if you don't know this process, my daughter illustrated it.🧬
www.biorxiv.org/content/10.1...
🧵 later, but if you don't know this process, my daughter illustrated it.🧬
www.biorxiv.org/content/10.1...
September 19, 2025 at 8:22 PM
new Lai lab #miRNA paper alert!! happy to share Renfu Shang's mechanistic insights into the mysteries of miRNA cluster assistance. wonderful collab with Niko Popitsch and @ameressl.bsky.social
🧵 later, but if you don't know this process, my daughter illustrated it.🧬
www.biorxiv.org/content/10.1...
🧵 later, but if you don't know this process, my daughter illustrated it.🧬
www.biorxiv.org/content/10.1...
Reposted by Dina Grohmann
Thank you for finding me here! I try to post new art every couple of days. My original works are temporary street art, but you can buy prints, books, calendars and postcards of their images at zinnart.com/store. Cheers!
Collections
Online store and information hub for the street art of ephemeral sidewalk chalk artist David Zinn, known for his cheerful 3D (three-dimensional) creatures including the stalk-eyed monster Sluggo, flyi...
zinnart.com
November 21, 2024 at 6:22 PM
Thank you for finding me here! I try to post new art every couple of days. My original works are temporary street art, but you can buy prints, books, calendars and postcards of their images at zinnart.com/store. Cheers!
Another great story from the Albers lab @archaellum.bsky.social 👍!! Congrats to all authors … exciting science ☺️!!! But how shall we name the motility structures now that archaellum is not exclusively reserved for Archaea any longer 😳??
Happy to share that our story on the bacterial archaellum was published today in @natmicrobiol.nature.com
www.nature.com/articles/s41...
Congrats to the authors: @sshamphavi.bsky.social @loumollat.bsky.social @mariejoest.bsky.social Najwa Taib and @sgribaldo.bsky.social
www.nature.com/articles/s41...
Congrats to the authors: @sshamphavi.bsky.social @loumollat.bsky.social @mariejoest.bsky.social Najwa Taib and @sgribaldo.bsky.social
September 17, 2025 at 5:44 PM
Another great story from the Albers lab @archaellum.bsky.social 👍!! Congrats to all authors … exciting science ☺️!!! But how shall we name the motility structures now that archaellum is not exclusively reserved for Archaea any longer 😳??
Reposted by Dina Grohmann
Archaeal Virus Ph.D. project! (With Tessa Quax)
www.rug.nl/about-ug/wor...
www.rug.nl/about-ug/wor...
Vacatures bij de RUG
www.rug.nl
September 12, 2025 at 4:34 AM
Archaeal Virus Ph.D. project! (With Tessa Quax)
www.rug.nl/about-ug/wor...
www.rug.nl/about-ug/wor...
Reposted by Dina Grohmann
Looking for a new approach to studying or eliminating phages? Check out our study introducing anti-phage ASOs (antisense oligos) out in @Nature today. nature.com/articles/s4158…
September 10, 2025 at 3:40 PM
Looking for a new approach to studying or eliminating phages? Check out our study introducing anti-phage ASOs (antisense oligos) out in @Nature today. nature.com/articles/s4158…
Reposted by Dina Grohmann
What is single-molecule FRET? Watch
@timcraggs.bsky.social
explain how this technique measures nanometer-scale distances and captures single-molecule conformations - youtu.be/BpCsTVJkQyE #structuralbiology #moleculardynamics #discovery #smFRET
@timcraggs.bsky.social
explain how this technique measures nanometer-scale distances and captures single-molecule conformations - youtu.be/BpCsTVJkQyE #structuralbiology #moleculardynamics #discovery #smFRET
What is single-molecule FRET?
YouTube video by Exciting Instruments
youtu.be
September 10, 2025 at 2:26 PM
What is single-molecule FRET? Watch
@timcraggs.bsky.social
explain how this technique measures nanometer-scale distances and captures single-molecule conformations - youtu.be/BpCsTVJkQyE #structuralbiology #moleculardynamics #discovery #smFRET
@timcraggs.bsky.social
explain how this technique measures nanometer-scale distances and captures single-molecule conformations - youtu.be/BpCsTVJkQyE #structuralbiology #moleculardynamics #discovery #smFRET