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Ferriol Calvet

@ferriol.bsky.social

75 followers 130 following 1 posts

PhD student in Cancer Genomics @bbglab.bsky.social @irbbarcelona.org

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Ferriol Calvet @ferriol.bsky.social · 22h

Very excited to share our new paper on the influence of biological sex and smoking in the clonal landscape of normal human bladder, just published in Nature.
A big thank you and congrats to all the authors, specially to @raquelbmi.bsky.social for all the shared efforts in this journey!

⬇️More info⬇️

Nuria Lopez-Bigas @nlbigas.bsky.social · 23h

🚨 New paper alert!

Sex and smoking bias in the selection of somatic mutations in human bladder

www.nature.com/articles/s41...

by @raquelbmi.bsky.social, @ferriol.bsky.social et al (in collaboration with Rosana Risques lab in @uwmedicine.bsky.social)

Sex and smoking bias in the selection of somatic mutations in human bladder - Nature

Sex bias and association with smoking history identified in the landscape of driver mutations and clonal expansions in normal human bladder tissue may explain the higher bladder cancer risk in men and smokers.

www.nature.com

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Ferriol Calvet @ferriol.bsky.social · 22h

Nuria Lopez-Bigas @nlbigas.bsky.social · 23h

Sex and smoking bias in the selection of somatic mutations in human bladder - Nature

www.nature.com

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Reposted by Ferriol Calvet

Nature @nature.com · 23h

Scientists have used low-error genome-sequencing methods in normal tissues from large cohorts of individuals to scan for mutations that set the stage for cancer

go.nature.com/42vakWS

Ultra-sensitive DNA sequencing maps mutations that precede cancer

Scientists have used low-error genome-sequencing methods in normal tissues from large cohorts of individuals to scan for mutations that set the stage for cancer.

go.nature.com

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Reposted by Ferriol Calvet

IRB Barcelona @irbbarcelona.org · 1d

🧪 Out in @nature.com: Smoking and biological sex shape healthy bladder tissue evolution, offering clues to #cancer risk.

✍️ #IRBBarcelona & University of Washington

➡️ bit.ly/42wcIN5

📌 DOI: 10.1038/s41586-025-09521-x

#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social

🧵👇

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Reposted by Ferriol Calvet

Cancer Grand Challenges @cancergrand.bsky.social · 1d

New research from team PROMINENT (@nlbigas.bsky.social), published in @nature.com, uncovers clues why men face a higher risk of bladder cancer and reveals that tobacco smoke acts as a promoter, not an initiator, in bladder cancer development.

Read more: www.cancergrandchallenges.org/news/early-c...

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Reposted by Ferriol Calvet

Wellcome Connecting Science Learning and Training @eventswcs.bsky.social · 24d

Join us for hands-on training in Cancer Genomic Epidemiology! #CancerEpi2026

Gain the expertise to use the tools and approaches to detect cancer mutations, and inform equitable prevention.

🗓️ 16-18 February 2026
Apply by 3 November - bursaries available

📎 bit.ly/41mRDnD
#OncSky #GeneSky 🧪🖥️🧬

Wellcome Connecting Science
Cancer Genomic Epidemiology 2026
Course dates: 16-18 February
Location: Wellcome Genome Campus, UK
Application deadline: 3 November 2025

Apply now

Image description: A group of course participants seated in a classroom. A speaker is standing at the front of the room, holding a microphone, and is addressing the room.

Reposted by Ferriol Calvet

Nuria Lopez-Bigas @nlbigas.bsky.social · Aug 14

New paper from our lab - ‪@bbglab.bsky.social‬.

Oncodrive3D: fast and accurate detection of structural clusters of somatic mutations under positive selection

academic.oup.com/nar/article/...

Kudos to Stefano, Olivia, @fmuinos.bsky.social and Abel

Oncodrive3D: fast and accurate detection of structural clusters of somatic mutations under positive selection

Abstract. Identifying the genes capable of driving tumorigenesis in different tissues is one of the central goals of cancer genomics. Computational methods

academic.oup.com

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Reposted by Ferriol Calvet

Raquel Blanco @raquelbmi.bsky.social · Jun 20

Back after a few days in Lisbon for the annual #EACR2025 conference! Inspiring and great science. Glad for the opportunity to present our work, coming home with a bunch of new ideas! @bbglab.bsky.social @ferriol.bsky.social

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Reposted by Ferriol Calvet

Ferran Muiños @fmuinos.bsky.social · May 22

Kudos to @raquelbmi.bsky.social and @ferriol.bsky.social, first authors of the study, for the insane amount of good work put into this.

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Reposted by Ferriol Calvet

Barcelona Biomedical Genomics Lab @bbglab.bsky.social · Apr 9

We are searching for a Bioinformatics Software Developer to work in Cancer Genomics:
recruitment.irbbarcelona.org/jobs/5793638...

Bioinformatics Software Developer in Cancer Genomics (ref. LAB/25/06) - IRB Barcelona

IRB Barcelona is seeking a talented and motivated Bioinformatics Software Developer (Research Assistant) to join the Biomedical Genomics Lab led by Dr. Núria López-Bigas at IRB Barcelona (bbglab.ir...

recruitment.irbbarcelona.org

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Reposted by Ferriol Calvet

Guigó Lab @guigolab.bsky.social · Mar 22

🚀 Our new paper is out! The BioGenome Portal: an open-source customizable platform for managing biodiversity genomics data 🧬🌍

doi.org/10.1093/narg...

@crg.eu @rodericguigo.bsky.social

#genomics #biodiversity

The BioGenome Portal: a web-based platform for biodiversity genomics data management

Abstract. Biodiversity genomics projects are underway with the aim of sequencing the genomes of all eukaryotic species on Earth. Here we describe the BioGe

academic.oup.com

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Reposted by Ferriol Calvet

Albert Vilella, PhD. @albertvilella.bsky.social · Feb 20

Will the world of short-read Next-Generation Sequencing change forever? We are about to find out! #Roche #SBX #ShortReads #NovaSeqKiller

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Reposted by Ferriol Calvet

Nature @nature.com · Jan 29

“The leaders of the Human Genome Project always knew they were just starting a conversation”

The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do

https://go.nature.com/3CupmSS

‘Dark proteins’ hiding in our cells could hold clues to cancer and other diseases

The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do.

go.nature.com

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Reposted by Ferriol Calvet

Marc de Manuel @marcdemanuel.bsky.social · Nov 25

📣 Two ERC-funded positions are available in the lab! If you are interested in exploring the mechanisms underlying mutation, we’d love to hear from you.

PhD: shorturl.at/Oc04N
Postdoc: shorturl.at/1ShHB

RPs and shares would be greatly appreciated!
🧪🧬🖥️ #ScienceJobs #PostdocJobs

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Reposted by Ferriol Calvet

Nuria Lopez-Bigas @nlbigas.bsky.social · Nov 25

We recently announced a dual new release of intOGen and boostDM

Computational analysis of 33,218 tumor genomes to identify cancer genes and driver mutations

➡️ Compendium of Cancer Driver Genes - www.intogen.org

➡️ In Silico Saturation Mutagenesis of Cancer Genes - www.intogen.org/boostdm

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