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Franco Della Felice

@francdefel.bsky.social

31 followers 30 following 8 posts

Associate Researcher at the University of Groningen - Artificial Enzyme Design & Biocatalysis - #GreenChemistry #ACSSustainabilityStar '24 #ChemSky

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Reposted by Franco Della Felice

Fabrizio Casilli @fabricas.bsky.social · Jul 4

📢 New publication alert 📢

🧪Studying enzyme conformational dynamics always hides new surprises, especially when you discover that beneficial mutations destabilize the enzyme!

Read more here ---> doi.org/10.1002/cbic...

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Franco Della Felice @francdefel.bsky.social · Jul 2

I am more than excited and grateful for such an opportunity at #Biotrans2025! The session was out of this world. Big thanks to the organizing committee. The Q&A and after session was fantastic.

Keep tuned for upcoming news!

#MSCA

Roelfes Group @roelfesgroup.bsky.social · Jul 1

Our postdoc @francdefel.bsky.social just gave a fantastic talk on gold-based artificial metalloenzymes for asymmetric catalysis. #Biotrans2025
@stratinghinst.bsky.social @rug.nl

Franco Della Felice @francdefel.bsky.social · Jun 26

Great experience at the Green Chemistry & Engineering Conference! Amazing time around a neat program.

Extremely grateful for giving me the chance to share my work in an environment that pushes towards sustainable research

#GreenChemistry #MSCA

@acsgci.bsky.social @roelfesgroup.bsky.social

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Reposted by Franco Della Felice

Roelfes Group @roelfesgroup.bsky.social · May 12

📢📢📢 PhD Opportunity!

Join our research group at RUG! We're seeking a motivated PhD student for a project on biocatalytic cascade processes combining natural and designer enzymes, supported by machine learning.
Click below to learn more — and feel free to share!

sites.google.com/rug.nl/roelf...

Roelfes group - Open Positions

PhD position on Hybrid biocatalytic cascades aided by Machine learning (1.0 FTE)

sites.google.com

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Franco Della Felice @francdefel.bsky.social · Apr 23

Updated link:
pubs.rsc.org/en/content/a...

Genetically encoded 3-aminotyrosine as catalytic residue in a designer Friedel–Crafts alkylase

Genetic incorporation of noncanonical amino acids (ncAAs) harbouring catalytic side chains into proteins allows the creation of enzymes able to catalyse reactions that have no equivalent in nature. He...

pubs.rsc.org

Reposted by Franco Della Felice

Chemical Science @chemicalscience.rsc.org · Apr 23

Check out this week’s #ChemSciPicks from Gerard Roelfes (@roelfesgroup.bsky.social, @stratinghinst.bsky.social) et al.!

‘Genetically Encoded 3-Aminotyrosine as Catalytic Residue in a Designer Friedel-Crafts Alkylase’

Read it here for free: doi.org/10.1039/D5SC...

#ChemSky 🧪

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Franco Della Felice @francdefel.bsky.social · Apr 23

Very happy to share our latest work on artificial enzyme catalysis in @chemicalscience.rsc.org! Very grateful for being a #ChemSciPicks.

📃 doi.org/10.1039/D5SC...

All my thanks to @brouwerb.bsky.social and @roelfesgroup.bsky.social

#OpenScience #MSCA

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Franco Della Felice @francdefel.bsky.social · Mar 27

Had an amazing week at #ACSSpring2025! It was an intense but incredibly rewarding experience with top speakers and insightful discussions. I'm grateful for the opportunity to present my research in the biocatalysis session - awesome interaction! #MSCA @roelfesgroup.bsky.social

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Franco Della Felice @francdefel.bsky.social · Mar 11

Happy to present my current work at N3C! Amazing conference with an excellent program💯💯

Roelfes Group @roelfesgroup.bsky.social · Mar 11

Our group members Tanja and Franco @francdefel.bsky.social presented their exciting research at NCCC this week.
Franco talked about his work on asymmetric catalysis in gold-based artificial metalloenzymes.

Franco Della Felice @francdefel.bsky.social · Feb 12

Grateful to be part of this awesome project lead by @brouwerb.bsky.social. Take a look to our preprint about unlocking iminium ion catalysis when using amino-tyrosine as a genetically encoded amino acid! 🤓
#MSCA @roelfesgroup.bsky.social

Bart Brouwer @brouwerb.bsky.social · Feb 11

Check out our latest preprint, in which we demonstrate the first example of using noncanonical 3-aminotyrosine (aY) as a catalytic residue for iminium activation in a designer enzyme!

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Franco Della Felice @francdefel.bsky.social · Dec 6

Excellent piece of work. Congrats to the whole team!

Roelfes Group @roelfesgroup.bsky.social · Dec 6

We are thrilled to share our new noble-metal enzyme design approach. We used the in-vivo incorporation of a noble-metal-binding ligand for ArM design to bridge the versatility of noble metals with the catalytic power of enzymes.
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