Lightnews — Scholar-powered news

François Mayer @francoismayer.bsky.social · 6d

Our October issue is out now!

The images are negatively stained electron micrographs taken from archaella bundles isolated from the archaeon Sulfolobus acidocaldarius.

Check the issue out here:
www.nature.com/nmicrobiol/v...

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Reposted by François Mayer

Nature Microbiology @natmicrobiol.nature.com · 13d

OUT NOW: Rational design of a hospital-specific phage cocktail to treat Enterobacter cloacae complex infections

By Dinesh Subedi, Jeremy Barr & colleagues @jeremyjbarr.bsky.social

www.nature.com/articles/s41...

Rational design of a hospital-specific phage cocktail to treat Enterobacter cloacae complex infections - Nature Microbiology

The Entelli-02 phage product containing five phages has frontline potential to address infections caused by the multidrug-resistant Enterobacter cloacae complex.

www.nature.com

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Reposted by François Mayer

Jeremy Barr @jeremyjbarr.bsky.social · 14d

Excited to annouce the latest research published by our lab, which is led by Dinesh Subedi and is out today in Nature Microbiology.

www.nature.com/articles/s41...

Rational design of a hospital-specific phage cocktail to treat Enterobacter cloacae complex infections - Nature Microbiology

The Entelli-02 phage product containing five phages has frontline potential to address infections caused by the multidrug-resistant Enterobacter cloacae complex.

www.nature.com

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Reposted by François Mayer

Nature Microbiology @natmicrobiol.nature.com · 15d

Deep-mining the archaeal proteome for antibiotics

News & Views by Rafael Laso-Pérez

@gecko1990.bsky.social @delafuentelab.bsky.social

Read it here: rdcu.be/eHNwa

Deep-mining the archaeal proteome for antibiotics

Nature Microbiology - A deep-learning algorithm unravels a collection of archaeasins, peptides from the archaeal proteome with potential antimicrobial activity and implications for the development...

rdcu.be

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Reposted by François Mayer

Matt Higgins @parasitematt.bsky.social · 22d

Delighted to review the latest findings on how malaria parasites get into our blood cells and how we might stop it!

Nature Reviews Microbiology @natrevmicro.nature.com · 23d

New online! Erythrocyte invasion in malaria: from molecular mechanisms to rational vaccines

Erythrocyte invasion in malaria: from molecular mechanisms to rational vaccines

Nature Reviews Microbiology, Published online: 15 September 2025; doi:10.1038/s41579-025-01235-1If erythrocyte invasion is blocked during the blood stage of infection by Plasmodium parasites, malaria can be prevented. In this Review, structural insights on erythrocyte invasion by the merozoite form of Plasmodium are discussed in the context of rational design of a blood-stage malaria vaccine.

www.nature.com

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François Mayer @francoismayer.bsky.social · Sep 4

September issue out now:

Read it here:
www.nature.com/nmicrobiol/v...

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Reposted by François Mayer

Amelia Barber @ameliabarberphd.bsky.social · Aug 14

Aspergillus fumigatus reference strain Af293 carries a mycovirus that boosts heat+oxidative stress resistance and infection fitness. 😲💥

I encourage you to check out Neta's thread and I'm delighted my group could play a small role in this exciting study!!

Neta Shlezinger @shlezingerlab.bsky.social · Aug 14

🚨 Fungi + viruses + mammalian lungs? Buckle up! Our new paper in
@natmicrobiol.nature.com
uncovers the story of a deadly fungus and its gnarly viral hitchhiker — and how this duo may change how we diagnose & treat fungal disease 🍄🫁🚨 doi.org/10.1038/s415... ⬇️

Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host - Nature Microbiology

A mycovirus infecting the pathogenic fungus Aspergillus fumigatus enhances its stress tolerance and virulence in mice.

doi.org

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Reposted by François Mayer

Neta Shlezinger @shlezingerlab.bsky.social · Aug 14

🚨 Fungi + viruses + mammalian lungs? Buckle up! Our new paper in
@natmicrobiol.nature.com
uncovers the story of a deadly fungus and its gnarly viral hitchhiker — and how this duo may change how we diagnose & treat fungal disease 🍄🫁🚨 doi.org/10.1038/s415... ⬇️

Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host - Nature Microbiology

A mycovirus infecting the pathogenic fungus Aspergillus fumigatus enhances its stress tolerance and virulence in mice.

doi.org

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François Mayer @francoismayer.bsky.social · Aug 14

Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host

Out now in Nature Microbiology, by Marina Rocha, Vanda Lerer, John Adeyemi Adeoye, Amelia Barber, Neta Shlezinger & colleagues

www.nature.com/articles/s41...

Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host - Nature Microbiology

A mycovirus infecting the pathogenic fungus Aspergillus fumigatus enhances its stress tolerance and virulence in mice.

www.nature.com

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François Mayer @francoismayer.bsky.social · Jul 31

Our August issue is now live - a special focus issue on ‚Strategies to overcome infectious disease‘

Read it here:

www.nature.com/nmicrobiol/v...

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Reposted by François Mayer

Nature Microbiology @natmicrobiol.nature.com · Jul 30

#NewResearch

'The food-associated resistome is shaped by processing and production environments' by @nmquijada.bsky.social and co-workers.

#MicroSky 🦠

www.nature.com/articles/s41...

The food-associated resistome is shaped by processing and production environments - Nature Microbiology

Whole-metagenome sequencing of 1,780 raw-material, end-product and surface samples from 113 food processing facilities reveals the occurrence of antimicrobial resistance determinants in foods and thei...

www.nature.com

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François Mayer @francoismayer.bsky.social · Jul 29

Evolution of antifungal resistance in the environment

New Review Article by @normanvanrhijn.bsky.social and @drjorhodes.com

Read it here: rdcu.be/eyobz

www.nature.com/articles/s41...

Evolution of antifungal resistance in the environment

Nature Microbiology - This Review discusses the evolution, emergence and expansion of environmental fungicide and antifungal drug resistance.

rdcu.be

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Reposted by François Mayer

Jo Rhodes @drjorhodes.com · Jul 29

A little holiday news:

Evolution of antifungal resistance in the environment www.nature.com/articles/s41...

This started out as a little thought way back in early 2024 between @normanvanrhijn.bsky.social and I, and turned into a full on review! We hope it proves useful to the community.

Evolution of antifungal resistance in the environment - Nature Microbiology

This Review discusses the evolution, emergence and expansion of environmental fungicide and antifungal drug resistance.

www.nature.com

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Reposted by François Mayer

Franklin Nobrega @fnobrega.bsky.social · Jul 28

Thrilled to see our Kiwa story out today! A membrane-associated supercomplex that senses infection and blocks replication and transcription.

www.cell.com/cell/fulltex...

Huge congratulations to Yi and Zhiying for bringing it home, to Thomas for starting us off, and to all the collaborators.

Kiwa is a membrane-embedded defense supercomplex activated at phage attachment sites

Zhang, Todeschini, and Wu et al. show that the bacterial defense system Kiwa senses phage attachment at the membrane and assembles a transmembrane complex that halts infection by blocking phage DNA re...

www.cell.com

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Reposted by François Mayer

Nature Microbiology @natmicrobiol.nature.com · Jul 15

Fighting malaria as a patient and scientist – new Microbe Matters by Fitsum Tadesse out now! #malaria #MicroSky

www.nature.com/articles/s41...

Fighting malaria as a patient and scientist - Nature Microbiology

Fitsum Tadesse was infected with malaria as a young child in Ethiopia and faced challenges to access efficacious treatment during a time of widespread drug resistance. Today, as a scientist in Africa,...

www.nature.com

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Reposted by François Mayer

Nature @nature.com · Jul 14

A potent bacterium in the human gut can supercharge the effects of some cancer drugs

go.nature.com/4lqaBBI

Found: a human gut microbe that makes cancer therapy more effective in mice

Cancer therapies called checkpoint inhibitor drugs, which ratchet up the immune system, work better when this bacterium is around.

go.nature.com

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Reposted by François Mayer

Magdalena Skipper @magdalenaskipper.bsky.social · Jul 11

This is quite astonishing - Scientists hide messages in papers to game AI peer review

Read this to find out how much you can fit into a single space after a full stop (if you use a very small font)

🧪 #AcademicSky

www.nature.com/articles/d41...

Scientists hide messages in papers to game AI peer review

Some studies containing instructions in white text or small font — visible only to machines — will be withdrawn from preprint servers.

www.nature.com

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Reposted by François Mayer

Nature Microbiology @natmicrobiol.nature.com · Jul 8

#NewResearch out now!

Giardia-induced Type 2 mucosal immunity attenuates intestinal inflammation in mice

#microsky

www.nature.com/articles/s41...

Giardia-induced Type 2 mucosal immunity attenuates intestinal inflammation caused by co-infection or colitis in mice - Nature Microbiology

A host–protist interaction regulates mucosal immunity to promote parasitism which also reduces the risk of inflammatory-driven pathologies of the gut.

www.nature.com

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François Mayer @francoismayer.bsky.social · Jul 3

Congratulations Linda!

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Reposted by François Mayer

Linda Horianopoulos @linder-surprise.bsky.social · Jul 1

Very happy to share our new paper on how machine learning predicts gene family expansions which contribute to oxidative stress resistance across diverse yeast species:

www.nature.com/articles/s41...

Machine learning reveals genes impacting oxidative stress resistance across yeasts - Nature Communications

Yeasts are exposed to oxidative stress during routine metabolism, bioproduction, and interactions with other organisms. Here, the authors use a machine learning classifier to identify genes that are p...

www.nature.com

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François Mayer @francoismayer.bsky.social · Jul 2

Straight from Antarctica: our new July issue has arrived!

Sample it here:
www.nature.com/nmicrobiol/v...

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François Mayer @francoismayer.bsky.social · Jun 30

Congrats!

Reposted by François Mayer

Jessica Bryant @jessmbryant.bsky.social · Jun 30

June was a productive month: brought two things into this world, both of which were great collaborative efforts and about nine months in the making. Check out where we map P. falciparum genome architecture at high resolution with Micro-C here:

www.nature.com/articles/s41...

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Reposted by François Mayer

Black Microbiologists Assoc (Black In Micro) @blackinmicro.bsky.social · Jun 26

Check out the latest Amplifying Diverse Voices journal club article written by BMA members Oluwatosin Orababa and Dr. Raphael P. Galleh!

www.nature.com/artic...

#BlackInMicro #AMR #antibiotics #JournalClub

Screen capture of the journal club article - title: A xanthone-derived antibiotic with a multifaceted mode of action. Authors: Oluwatosin Orababa and Dr. Raphael P. Galleh.

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Reposted by François Mayer

Parul Singh @singh-parul.bsky.social · Jun 30

Super excited for this study. Congratulations to other authors and grateful to the reviewers for their constructive comments. Great collaboration with Jacques Serizay, @ju-couble.bsky.social, @sebbaumgarten.bsky.social under the stellar supervision of @jessmbryant.bsky.social

François Mayer @francoismayer.bsky.social · Jun 30

New study provides insight into the organizational machinery used by the malaria parasite to spatially coordinate genes and regulate transcription.

@jessmbryant.bsky.social sky.social @singh-parul.bsky.social
@ju-couble.bsky.social

www.nature.com/articles/s41...

High-resolution map of the Plasmodium falciparum genome reveals MORC/ApiAP2-mediated links between distant, functionally related genes - Nature Microbiology

Micro-C provides insights into genome organization in Plasmodium falciparum and defines the machinery used to spatially coordinate antigenic variation and stage-specific genes that are crucial for inf...

www.nature.com

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